Výsledky vyhledávání - "MESH: Suppressor of Cytokine Signaling Proteins"

LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice.: LEPROTs decrease growth hormone signaling

Autor: Céline Cudejko, Eric Bauge, Jean-Pierre Salles, Réjane Paumelle, Thierry Touvier, Bernard Bailleul, Olivier Briand, Bart Staels, Sandrine Caron, Francoise Conte-Auriol, Yves Rouillé

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2009, 119 (12), pp.3830-8. ⟨10.1172/JCI34997⟩

International audience; Growth hormone (GH) is a major metabolic regulator that functions by stimulating lipolysis, preventing protein catabolism, and decreasing insulin-dependent glucose disposal. Modulation of hepatic sensitivity to GH and the down

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4507b5664899b1e65d3ac3d7f43d44d5
https://doi.org/10.1172/jci34997

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Induction of interleukin-10 and suppressor of cytokine signalling-3 gene expression following peptide immunotherapy

Autor: Adrienne Verhoef, Bernard Maillere, Cezmi A. Akdis, M. D. Tarzi, S. Klunker, A. B. Kay, Catherine Texier, S. O. Stapel, Mark Larché

Publikováno v: Clinical and Experimental Allergy
Clinical and Experimental Allergy, Wiley, 2006, 36 (4), pp.465-74. ⟨10.1111/j.1365-2222.2006.02469.x⟩

International audience; BACKGROUND: Allergen-derived (T cell epitope) peptides may be safer for immunotherapy than native allergen, as they do not cross-link immunoglobulin (Ig)E. However, HLA polymorphism results in multiple potential epitopes. Synt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ce1884c4adc3079cf9afb5b1d65d37
https://doi.org/10.1111/j.1365-2222.2006.02469.x

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LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice

Autor: Touvier, Thierry, Conte-Auriol, Françoise, Briand, Olivier, Cudejko, Céline, Paumelle, Réjane, Caron, Sandrine, Baugé, Eric, Rouillé, Yves, Salles, Jean-Pierre, Staels, Bart, Bailleul, Bernard

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, 2009, 119 (12), pp.3830-8. ⟨10.1172/JCI34997⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::dc30eda43edc8180070f6d4be8e29ca6
https://www.hal.inserm.fr/inserm-00432067/file/LEPROT.pdf

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LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2009, 119 (12), pp.3830-8. ⟨10.1172/JCI34997⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::dc30eda43edc8180070f6d4be8e29ca6
https://www.hal.inserm.fr/inserm-00432067/file/LEPROT.pdf

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SOCS3 inhibits TPO-stimulated, but not spontaneous, megakaryocytic growth in primary myelofibrosis

Autor: Stéphane Giraudier, Carole Tonetti, Jean-Jacques Kiladjian, Rodolphe Besancenot, Gérard Socié, Dominique Bordessoule, Ronan Chaligne, William Vainchenker, Caroline Marty

Publikováno v: Leukemia
Leukemia, 2009, 23 (6), pp.1186-90. ⟨10.1038/leu.2009.22⟩
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2009, 23 (6), pp.1186-90. ⟨10.1038/leu.2009.22⟩

SOCS3 inhibits TPO-stimulated, but not spontaneous, megakaryocytic growth in primary myelofibrosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43a0976e71a7b0bc8ff02968a71d618
https://hal.archives-ouvertes.fr/hal-00453235

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Cutting edge: innate immune response triggered by influenza A virus is negatively regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-dependent pathway

Autor: Mustapha Si-Tahar, Julien Pothlichet, Michel Chignard

Publikováno v: Journal of Immunology
Journal of Immunology, 2008, 180 (4), pp.2034-2038. ⟨10.4049/jimmunol.180.4.2034⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 180 (4), pp.2034-2038. ⟨10.4049/jimmunol.180.4.2034⟩

Influenza A virus (IAV) triggers a contagious respiratory disease that produces considerable lethality. Although this lethality is likely due to an excessive host inflammatory response, the negative feedback mechanisms aimed at regulating such a resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18420b52ad8171e486d3493074891516
https://hal-pasteur.archives-ouvertes.fr/pasteur-00206322/document

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Prolonged inflammatory gene response following soman-induced seizures in mice

Autor: André Peinnequin, Franck Dhote, Frédéric Dorandeu, Annie Foquin, Pierre Carpentier, Guy Lallement, Claire Delacour, Valérie Baille

Publikováno v: Toxicology
Toxicology, Elsevier, 2007, 238 (2-3), pp.166-76. ⟨10.1016/j.tox.2007.05.032⟩

International audience; Following exposure to the organophosphorus nerve agent soman, the development of long-lasting seizures and build-up of irreversible seizure-related brain damage (SRBD) still represent a therapeutic challenge. A neuro-inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756c71aa60e6136d08e28474c85259cc
https://pubmed.ncbi.nlm.nih.gov/17662515

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Distinct impaired regulation of SOCS3 and long and short isoforms of the leptin receptor in visceral and subcutaneous fat of lean and obese women

Autor: Javier Gómez-Ambrosi, Laetitia Corset, Gema Frühbeck, Francis Vasseur, Javier Salvador, Philippe Froguel, Philippe Boutin, Karin Séron

Publikováno v: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2006, 348 (4), pp.1232-8. ⟨10.1016/j.bbrc.2006.07.068⟩
Biochemical and Biophysical Research Communications, Elsevier, 2006, 348, pp.1232-8

Animal studies have illustrated the importance of the expression in adipose tissue of the leptin receptor (OB-R), and of SOCS3 an inhibitor of the leptin signaling pathway, in body weight regulation. The aim of the present study was to investigate in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b7bc40ee7127632b6c6b4647c2c60a
https://hal.archives-ouvertes.fr/hal-00174362

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Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3

Autor: Elisa Bergamin, Jinhua Wu, Stevan R. Hubbard

Publikováno v: Structure
Structure, Elsevier (Cell Press), 2006, 14 (8), pp.1285-1292. ⟨10.1016/j.str.2006.06.011⟩

International audience; Suppressor of cytokine signaling (SOCS) proteins are indispensable negative regulators of cytokine-stimulated Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathways. SOCS proteins (SOCS1-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e011b7712174e8a21c8b998e5e57f0
https://pubmed.ncbi.nlm.nih.gov/16905102

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The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells

Autor: Brice Emanuelli, Emmanuel Van Obberghen, Pascal Peraldi, Murielle Glondu, Chantal Filloux

Publikováno v: Diabetes
Diabetes, American Diabetes Association, 2004, 53 Suppl 3, pp.S97-S103

International audience; Defects in insulin secretion, resulting from loss of function or destruction of pancreatic beta-cells, trigger diabetes. Interleukin (IL)-1beta is a proinflammatory cytokine that is involved in type 1 and type 2 diabetes devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799145a8c8df9307204e9e86cbf0c338
https://pubmed.ncbi.nlm.nih.gov/15561930

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