Výsledky vyhledávání - "MESH: Sulfotransferases"

Expression and purification of recombinant extracellular sulfatase HSulf-2 allows deciphering of enzyme sub-domain coordinated role for the binding and 6-O-desulfation of heparan sulfate

Autor: Amal Seffouh, Hugues Lortat-Jacob, Zahra el Oula Hassoun, Rana El Masri, Jean-Pierre Andrieu, Romain R. Vivès, Evelyne Gout, Olga Makshakova

Publikováno v: Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2019
Cellular and Molecular Life Sciences, 2019, 76 (9), pp.1807-1819. ⟨10.1007/s00018-019-03027-2⟩
Cellular and Molecular Life Sciences, Springer Verlag, 2019, 76 (9), pp.1807-1819. ⟨10.1007/s00018-019-03027-2⟩

International audience; Through their ability to edit 6-O-sulfation pattern of Heparan sulfate (HS) polysaccharides, Sulf extracellular endosulfatases have emerged as critical regulators of many biological processes, including tumor progression. Howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae15b122eecdbac9b061ca2c582b74d
https://hal.archives-ouvertes.fr/hal-02043605

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Joint ancestry and association test indicate two distinct pathogenic pathways involved in classical dengue fever and dengue shock syndrome

Autor: Bruno Cavadas, Luísa Pereira, Fanny Koeth, Etienne Simon-Loriere, Marisa Oliveira, Isabelle Casademont, Worachart Lert-itthiporn, Prida Malasit, Orlando Anunciação, Prapat Suriyaphol, Marina Penova, Richard Paul, Fumihiko Matsuda, Chiea Chuen Khor, Ampaiwan Chuansumrit, Kanchana Tangnararatchakit, Anavaj Sakuntabhai, Verónica Fernandes

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 2, p e0006202 (2018)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2018, 12 (2), pp.e0006202. ⟨10.1371/journal.pntd.0006202⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Neglected Tropical Diseases, 2018, 12 (2), pp.e0006202. ⟨10.1371/journal.pntd.0006202⟩

Ethnic diversity has been long considered as one of the factors explaining why the severe forms of dengue are more prevalent in Southeast Asia than anywhere else. Here we take advantage of the admixed profile of Southeast Asians to perform coupled as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703f94848c2ae01c7d9157d78e7284e1
http://europepmc.org/articles/PMC5813895?pdf=render

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Induction of Reactive Oxygen Species by Human T-Cell Leukemia Virus Type 1 Tax Correlates with DNA Damage and Expression of Cellular Senescence Marker

Autor: Kuan-Teh Jeang, Jean-Marie Peloponese, Julia Ham-Terhune, Takao Kinjo

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2010, 84 (10), pp.5431-7. ⟨10.1128/JVI.02460-09⟩

Human T-cell leukemia virus type 1 (HTLV-1) Tax affects cellular genomic stability and senescence. As yet, the mechanism(s) for these events caused by Tax is incompletely understood. Here, we show that Tax expression in primary human cells induces re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549613e09fd8d23c6579a733f9ded6cf
https://doi.org/10.1128/jvi.02460-09

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Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes

Autor: Norbert Latruffe, Marie-Christine Chagnon, Nathalie Hanet, Jean-Marie Heydel, Gérard Lizard, Allan Lançon, Dominique Delmas, Brigitte Jannin, Yves Artur

Publikováno v: Drug Metabolism and Disposition
Drug Metabolism and Disposition, American Society for Pharmacology and Experimental Therapeutics (ASPET), 2007, 35 (5), pp.699-703. ⟨10.1124/dmd.106.013664⟩
Drug Metabolism and Disposition, American Society for Pharmacology and Experimental Therapeutics (ASPET), 2007, 35 (5), pp.699-703. 〈10.1124/dmd.106.013664〉

trans-Resveratrol is a polyphenol present in several plant species. Its chemopreventive properties against several diseases have been largely documented. To validate a model for the study of the factors influencing its biological fate at the hepatic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861af0cd9770c3304c8314b29fe10d59
https://hal.archives-ouvertes.fr/hal-00259260/file/Lancon_2007_DMD.pdf

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TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells

Publikováno v: Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2013, 15 (7), pp.818-828. ⟨10.1038/ncb2774⟩
Nature Cell Biology; Vol 15
Nature Cell Biology, 2013, 15 (7), pp.818-828. ⟨10.1038/ncb2774⟩

International audience; Dysfunctional telomeres suppress tumour progression by activating cell-intrinsic programs that lead to growth arrest. Increased levels of TRF2, a key factor in telomere protection, are observed in various human malignancies an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781bbc26cab786135940fe94a1b93c71
https://hal.archives-ouvertes.fr/hal-03510917

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GLADX: an automated approach to analyze the lineage-specific loss and pseudogenization of genes

Autor: Dainat, Jacques, Paganini, Julien, Pontarotti, Pierre, Gouret, Philippe

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e38792. ⟨10.1371/journal.pone.0038792⟩
PLoS ONE, Vol 7, Iss 6, p e38792 (2012)
PLoS ONE, 2012, 7 (6), pp.e38792. ⟨10.1371/journal.pone.0038792⟩

International audience; A well-established ancestral gene can usually be found, in one or multiple copies, in different descendant species. Sometimes during the course of evolution, all the representatives of a well-established ancestral gene disappe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1ecfe296efdcd14c4b62ed09e2551d02
https://hal.archives-ouvertes.fr/hal-00831091

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Synthesis of heparan sulfate with cyclophilin B-binding properties is determined by cell type-specific expression of sulfotransferases

Autor: Toin H. van Kuppevelt, Audrey Deligny, Adeline Marcant, Fabrice Allain, Aurélie Melchior, Agnès Denys, Joël Mazurier

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (3), pp.1701-15. ⟨10.1074/jbc.M109.018184⟩
Journal of Biological Chemistry, 285, 3, pp. 1701-15
Journal of Biological Chemistry, 2010, 285 (3), pp.1701-15. ⟨10.1074/jbc.M109.018184⟩
Journal of Biological Chemistry, 285, 1701-15

Contains fulltext : 89091.pdf (Publisher’s version ) (Open Access) Cyclophilin B (CyPB) induces migration and adhesion of T lymphocytes via a mechanism that requires interaction with 3-O-sulfated heparan sulfate (HS). HS biosynthesis is a complex p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77864e431b97c815fd04af9f417eebd
https://hal.archives-ouvertes.fr/hal-00469786

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SUMO is Growing Senescent

Autor: Anne Dejean, Oliver Bischof

Publikováno v: Cell Cycle
Cell Cycle, 2007, 6 (6), pp.677-681. ⟨10.4161/cc.6.6.4021⟩
Cell Cycle, Taylor & Francis, 2007, 6 (6), pp.677-681. ⟨10.4161/cc.6.6.4021⟩

International audience; Cellular senescence is an irreversible cell cycle arrest that curbs unrestrained, aberrant proliferation of mammalian cells and is now recognized as a prominent tumor suppressive mechanism. We have shown recently that the E3 S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb4be96abe2bc368752e03016f52868
https://hal-pasteur.archives-ouvertes.fr/pasteur-03236941

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