Two KTR Mannosyltransferases Are Responsible for the Biosynthesis of Cell Wall Mannans and Control Polarized Growth in Aspergillus fumigatus

Autor: Jizhou Li, Laura Alcazar-Fuoli, Emilia Mellado, Rémi Beau, Jean-Paul Latgé, Grégory Jouvion, Christine Henry, Thierry Fontaine, François Danion

Publikováno v: mBio, Vol 10, Iss 1 (2019)
mBio
mBio, American Society for Microbiology, 2019, 10 (1), pp.e02647-18. ⟨10.1128/mBio.02647-18⟩
mBio, 2019, 10 (1), pp.e02647-18. ⟨10.1128/mBio.02647-18⟩
mBio, Vol 10, Iss 1, p e02647-18 (2019)
Repisalud
Instituto de Salud Carlos III (ISCIII)

The fungal cell wall is a complex and dynamic entity essential for the development of fungi. It allows fungal pathogens to survive environmental challenge posed by nutrient stress and host defenses, and it also is central to polarized growth. The cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568619102a05c1f9cc92f6c3522aec94
https://journals.asm.org/doi/10.1128/mBio.02647-18

Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus

Autor: Mark H. T. Stappers, Matteo Zanda, Axel A. Brakhage, Mihai G. Netea, Ivy M. Dambuza, António Campos, Delyth M. Reid, Ten Feizi, Carol Wallace, Betty Hebecker, Jean-Paul Latgé, João F. Lacerda, Neil A. R. Gow, Frank L. van de Veerdonk, Maria da Glória Teixeira de Sousa, Patawee Asamaphan, Kyung J. Kwon-Chung, Monica Piras, Martin Jaeger, Cristina Cunha, Vishukumar Aimanianda, Janet A. Willment, Alexandra E. Clark, Raif Yuecel, Chiara Zanato, Isabel Valsecchi, Yan Liu, Agostinho Carvalho, Bernhard Kerscher, Sarah E. Hardison, Anthony Plato, Stefan Bidula, Gordon D. Brown

Publikováno v: Nature, 555, 7696, pp. 382-386
Nature
Nature, Nature Publishing Group, 2018, 555 (7696), pp.382-386. ⟨10.1038/nature25974⟩
Nature, 555, 382-386
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature, 2018, 555 (7696), pp.382-386. ⟨10.1038/nature25974⟩

© 2018 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
Resistance to infection is critically dependent on the ability of pattern recognition receptors to recognize microbial invasion and induce protective immune resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff61ca704d5de2aa7a584d3e436cd0b3
https://hdl.handle.net/2066/190136

Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge

Autor: Oumaïma Ibrahim-Granet, Amélie Savers, Bernhard Ryffel, Marianna Parlato, Gérard Eberl, Grégory Jouvion, Jean-Marc Cavaillon, Orhan Rasid, Matthias Brock

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2016, 11 (4), pp.e0153829. 〈10.1371/journal.pone.0153829〉
PLoS ONE, Public Library of Science, 2016, 11 (4), pp.e0153829. ⟨10.1371/journal.pone.0153829⟩
PLoS ONE, 2016, 11 (4), pp.e0153829. ⟨10.1371/journal.pone.0153829⟩
PLoS ONE, Vol 11, Iss 4, p e0153829 (2016)

International audience; Phagocytes restrict the germination of Aspergillus fumigatus conidia and prevent the establishment of invasive pulmonary aspergillosis in immunecompetent mice. Here we report that immunecompetent mice recovering from a primary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f8cdc99a7fc230687dff47ab64c555
https://hal-pasteur.archives-ouvertes.fr/pasteur-01448226/file/2016.Plos.One.Aspergillus.pdf

Deciphering the role of the chitin synthase families 1 and 2 in the in vivo and in vitro growth of Aspergillus fumigatus by multiple gene targeting deletion

Autor: Muszkieta, Laetitia, Aimanianda, Vishukumar, Mellado, Emilia, Gribaldo, Simonetta, Alcazar-Fuoli, Laura, Szewczyk, Edyta, Prevost, Marie-Christine, Latgé, Jean-Paul

Publikováno v: Cellular Microbiology
Cellular Microbiology, Wiley, 2014, 16 (12), pp.1784-1805. ⟨10.1111/cmi.12326⟩
Cellular Microbiology, 2014, 16 (12), pp.1784-1805. ⟨10.1111/cmi.12326⟩

International audience; Although chitin is an essential component of the fungal cell wall (CW), its biosynthesis and role in virulence is poorly understood. In Aspergillus fumigatus, there are eight chitin synthase (CHS) genes belonging to two famili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::88bf1542bb2388ddc5e6646f910a9aed
https://hal-pasteur.archives-ouvertes.fr/pasteur-02445787

Community-acquired invasive aspergillosis and outdoor filamentous fungal spore load: a relationship?

Autor: Marie-Pierre Brenier-Pinchart, Lysiane Molina, Frédéric Garban, Jean-Louis Quesada, Marie-Reine Mallaret, A. Thiebaut-Bertrand, J.L. Bosson, B. Lebeau, Jean-Paul Brion, Hervé Pelloux, R. Grillot, J.-L. Borel

Publikováno v: Clinical Microbiology and Infection
Clinical Microbiology and Infection, Elsevier for the European Society of Clinical Microbiology and Infectious Diseases, 2011, 17 (9), pp.1387-90. ⟨10.1111/j.1469-0691.2011.03523.x⟩

International audience; The daily number of outdoor spores was counted and the cases of community-acquired invasive aspergillosis (IA) were observed over a period of 31 months. The outdoor fungal load preceding IA occurrences was significantly higher

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724af5a907f77daae57aa9e3a1b6f42b
https://doi.org/10.1111/j.1469-0691.2011.03523.x