Zobrazeno 1 - 10
of 11
pro vyhledávání: '"MESH: Spermine"'
Autor:
Matthew L. Albert, Marie-Pascale Frenkiel, Anavaj Sakuntabhai, Carole Tamietti, Anna Yakovleva, Marco Vignuzzi, Francis Delpeyroux, Bryan C. Mounce, Sandrine Vitry, Scott W. Werneke, Etienne Simon-Loriere, Cécile Khou, Everett Clinton Smith, Mark R. Denison, Nathalie Pardigon, Marie Flamand, Peter Jan Hooikaas, Enzo Z. Poirier, Teresa Cesaro, Gonzalo Moratorio, Matthieu Prot, Monique Lafon, Romain Volle, Giovanna Barba-Spaeth
Publikováno v:
Journal of Virology
Journal of Virology, 2016, 90 (21), pp.9683-9692. ⟨10.1128/JVI.01347-16⟩
Journal of Virology, American Society for Microbiology, 2016, 90 (21), pp.9683-9692. ⟨10.1128/JVI.01347-16⟩
Journal of Virology, 2016, 90 (21), pp.9683-9692. ⟨10.1128/JVI.01347-16⟩
Journal of Virology, American Society for Microbiology, 2016, 90 (21), pp.9683-9692. ⟨10.1128/JVI.01347-16⟩
RNA viruses present an extraordinary threat to human health, given their sudden and unpredictable appearance, the potential for rapid spread among the human population, and their ability to evolve resistance to antiviral therapies. The recent emergen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b99549b02c685e1b3e4c5f33cb0ff75
https://hal-pasteur.archives-ouvertes.fr/pasteur-01402012
https://hal-pasteur.archives-ouvertes.fr/pasteur-01402012
Autor:
Jean Pierre Mbakidi, Pierre Krausz, Vincent Sol, Guillaume Garcia, Robert Granet, Caroline Le Morvan, Gaëlle Bégaud-Grimaud, Vincent Sarrazy
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology
Journal of Photochemistry and Photobiology B: Biology, Elsevier, 2011, 103 (3), pp.201-6. ⟨10.1016/j.jphotobiol.2011.03.005⟩
Journal of Photochemistry and Photobiology B: Biology, Elsevier, 2011, 103 (3), pp.201-6. ⟨10.1016/j.jphotobiol.2011.03.005⟩
International audience; Porphyrin-polyamine conjugates bearing two (cis or trans position) or four spermidine or spermine units were synthesized. We studied the photostability, the hydrophilic/lipophilic balance of porphyrin-polyamine derivatives and
Autor:
Giovanni Lughezzani, Françoise Bouet, Nathalie Rioux-Leclercq, Jean Jacques Patard, B. Cipolla, Pierre I. Karakiewicz, Jean Philippe Moulinoux, Véronique Catros-Quemener, Paul Perrotte, Pierre Bigot
Publikováno v:
Journal of Urology
Journal of Urology, Elsevier, 2010, 183 (2), pp.486-91. ⟨10.1016/j.juro.2009.10.012⟩
Journal of Urology, 2010, 183 (2), pp.486-91. ⟨10.1016/j.juro.2009.10.012⟩
Journal of Urology, Elsevier, 2010, 183 (2), pp.486-91. ⟨10.1016/j.juro.2009.10.012⟩
Journal of Urology, 2010, 183 (2), pp.486-91. ⟨10.1016/j.juro.2009.10.012⟩
International audience; PURPOSE: The polyamines spermine and spermidine are ubiquitous polycationic structures which are essential for cell proliferation and differentiation. Circulating polyamines, spermine and spermidine, represent valuable prognos
Autor:
D. Ruffieux, Alain Favier, François Berger, Véronique Ducros, Florence de Fraipont, Hélène Belva-Besnet
Publikováno v:
Analytical Biochemistry
Analytical Biochemistry, Elsevier Masson, 2009, 390 (1), pp.46-51. ⟨10.1016/j.ab.2009.04.007⟩
Analytical Biochemistry, Elsevier Masson, 2009, 390 (1), pp.46-51. ⟨10.1016/j.ab.2009.04.007⟩
International audience; The concentration of polyamines in red blood cells (RBCs) is considered to be an index of cell proliferation. This index has been demonstrated to be of clinical importance for the follow-up and treatment of some cancer patient
Autor:
Malene Ringkjøbing Jensen, Wolfgang Peti, Dorothy Koveal, Sai Dipikaa Akshinthala, Daniel H. Miller, Carla-Maria Gauss, Nicholas K. Tonks, Senthil K. Muthuswamy, Martin Blackledge, Navasona Krishnan, Jaka Kragelj, Rebecca Page, Bin Xue
Publikováno v:
Nature Chemical Biology
Nature Chemical Biology, 2014, 10 (7), pp.558-66
Nature Chemical Biology, Nature Publishing Group, 2014, 10 (7), pp.558-66
Nature chemical biology
Nature Chemical Biology, 2014, 10 (7), pp.558-66
Nature Chemical Biology, Nature Publishing Group, 2014, 10 (7), pp.558-66
Nature chemical biology
International audience; PTP1B, a validated therapeutic target for diabetes and obesity, has a critical positive role in HER2 signaling in breast tumorigenesis. Efforts to develop therapeutic inhibitors of PTP1B have been frustrated by the chemical pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618e0db7058ee681ab04620ad34e6881
https://hal.univ-grenoble-alpes.fr/hal-01131138
https://hal.univ-grenoble-alpes.fr/hal-01131138
Publikováno v:
Neuron
Neuron, Elsevier, 1995, 15 (5), pp.1109-20
Neuron, Elsevier, 1995, 15 (5), pp.1109-20
Extracellular Mg2+, which blocks NMDA channels in a voltage-dependent manner and increases the receptor's affinity for glycine, is shown here to potentiate NMDA responses at saturating glycine concentrations. This potentiation, induced by millimolar
Autor:
Valentina Battaglia, Marcantonio Bragadin, Francesca Zonta, Antonio Toninello, Pamela Martinis, Elena Tibaldi, Silvia Grancara, Anna Maria Brunati, Maria Angelica Grillo, Enzo Agostinelli, G. Tempera
Publikováno v:
Amino Acids
Amino Acids, Springer Verlag, 2012, 42 (2-3), pp.741-9. ⟨10.1007/s00726-011-0990-3⟩
Amino Acids, Springer Verlag, 2012, 42 (2-3), pp.741-9. ⟨10.1007/s00726-011-0990-3⟩
International audience; The polyamine spermine is transported into the matrix of various types of mitochondria by a specific uniporter system identified as a protein channel. This mechanism is regulated by the membrane potential; other regulatory eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1091d9a8ece0fa88fd0d8d8e9f03afd3
http://hdl.handle.net/10278/29259
http://hdl.handle.net/10278/29259
Autor:
Stephane Duhieu, Bénédicte Martin, Jean-Guy Delcros, Philippe Uriac, Myriam Le Roch, Jacques Renault, Sophie Tomasi, Virginie Cerec
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (21), pp.7647-63. ⟨10.1021/jm1007648⟩
Journal of Medicinal Chemistry, 2010, 53 (21), pp.7647-63. ⟨10.1021/jm1007648⟩
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (21), pp.7647-63. ⟨10.1021/jm1007648⟩
Journal of Medicinal Chemistry, 2010, 53 (21), pp.7647-63. ⟨10.1021/jm1007648⟩
International audience; The polyamine transport system (PTS) whose activity is up-regulated in cancer cells is an attractive target for drug design. Two heterocyclic (azepine and benzazepine) systems were conjugated to various polyamine moieties thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86161aacaf743b1aeefb64fb802b848
https://hal.archives-ouvertes.fr/hal-00752582
https://hal.archives-ouvertes.fr/hal-00752582
Autor:
Olivier Levillain, Florence Morfin, Aleth Callé, Myriam Cayre, Jean-Jacques Diaz, Laetitia Martin, Karine Kindbeiter, Danielle Thouvenot, Anna Greco
Publikováno v:
FASEB Journal
FASEB Journal, 2005, pp.1130
FASEB Journal, Federation of American Society of Experimental Biology, 2005, 19 (9), pp.1128-30. ⟨10.1096/fj.04-2108fje⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2005, pp.1130
FASEB Journal, 2005, pp.1130
FASEB Journal, Federation of American Society of Experimental Biology, 2005, 19 (9), pp.1128-30. ⟨10.1096/fj.04-2108fje⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2005, pp.1130
All the available antiherpetic drugs are directed against viral proteins. Their extensive clinical use has led to the emergence of resistant viral strains. There is a need for the treatment of herpes infections due to resistant strains, especially fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2f0e2f07324816b9b9d92df6cc5087
https://hal.science/hal-00124242
https://hal.science/hal-00124242
Autor:
Sandra Fouace, Cyril Gaudin, Sophie Corvaisier, Bertrand Carboni, Jacques Renault, Brice Felden, Sylvie Picard
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2004, 32 (1), pp.151-157. ⟨10.1093/nar/gkh157⟩
Nucleic Acids Research, 2004, 32 (1), pp.151-7. ⟨10.1093/nar/gkh157⟩
Nucleic Acids Research, Oxford University Press, 2004, 32 (1), pp.151-7. ⟨10.1093/nar/gkh157⟩
Nucleic Acids Research, 2004, 32 (1), pp.151-157. ⟨10.1093/nar/gkh157⟩
Nucleic Acids Research, Oxford University Press, 2004, 32 (1), pp.151-157. ⟨10.1093/nar/gkh157⟩
Nucleic Acids Research, 2004, 32 (1), pp.151-7. ⟨10.1093/nar/gkh157⟩
Nucleic Acids Research, Oxford University Press, 2004, 32 (1), pp.151-7. ⟨10.1093/nar/gkh157⟩
Nucleic Acids Research, 2004, 32 (1), pp.151-157. ⟨10.1093/nar/gkh157⟩
International audience; Site-selective scission of ribonucleic acids (RNAs) has attracted considerable interest, since RNA is an intermediate in gene expression and the genetic material of many pathogenic viruses. Polyamine-imidazole conjugates for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c68c1496fc52e575c42a076b2ef8a10
https://hal-normandie-univ.archives-ouvertes.fr/hal-02262532
https://hal-normandie-univ.archives-ouvertes.fr/hal-02262532