Zobrazeno 1 - 10
of 644
pro vyhledávání: '"MESH: Recombinant Proteins"'
Autor:
Fournes, Florian, Niault, Theophile, Czarnecki, Jakub, Tissier-Visconti, Alvise, Mazel, Didier, Val, Marie-Eve
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2021, 49 (19), pp.11119-11133. ⟨10.1093/nar/gkab903⟩
Nucleic Acids Research, Oxford University Press, 2021, 49 (19), pp.11119-11133. ⟨10.1093/nar/gkab903⟩
Nucleic Acids Research, 2021, 49 (19), pp.11119-11133. ⟨10.1093/nar/gkab903⟩
Nucleic Acids Research, Oxford University Press, 2021, 49 (19), pp.11119-11133. ⟨10.1093/nar/gkab903⟩
International audience; Vibrio cholerae, the pathogenic bacterium that causes cholera, has two chromosomes (Chr1, Chr2) that replicate in a well-orchestrated sequence. Chr2 initiation is triggered only after the replication of the crtS site on Chr1.
Autor:
François Bulteau, Michel Thépaut, Maxime Henry, Amandine Hurbin, Laetitia Vanwonterghem, Corinne Vivès, Aline Le Roy, Christine Ebel, Olivier Renaudet, Franck Fieschi, Jean-Luc Coll
Publikováno v:
Molecular Pharmaceutics
Molecular Pharmaceutics, 2022, 19 (1), pp.235-245. ⟨10.1021/acs.molpharmaceut.1c00744⟩
Molecular Pharmaceutics, 2022, 19 (1), pp.235-245. ⟨10.1021/acs.molpharmaceut.1c00744⟩
International audience; Alterations in glycosylation cause the emergence of tumor-associated carbohydrate antigens (TACAs) during tumorigenesis. Truncation of O-glycans reveals the Thomsen nouveau (Tn) antigen, an N-acetylgalactosamine (GalNAc) frequ
Autor:
Jiho Kim, Bing-Mae Chen, Audrey Germond, Roffler Steve, Sucheol Gil, Laxman Savergave, Sanjay Singh, Hongjie Wang, Chang Li, Andre Lieber, Pascal Fender, Darrick Carter, Audrey Baldessari, Arjun Raghuwanshi, Charles W. Drescher, Swarnendu Kaviraj
Publikováno v:
Scientific Reports
Scientific Reports, 2022, 12, pp.7753. ⟨10.1038/s41598-022-11843-z⟩
Scientific Reports, 2022, 12, pp.7753. ⟨10.1038/s41598-022-11843-z⟩
Our goal is to overcome treatment resistance in ovarian cancer patients which occurs in most cases after an initial positive response to chemotherapy. A central resistance mechanism is the maintenance of desmoglein-2 (DSG2) positive tight junctions b
Autor:
de Krijger, Inge, Föhr, Bastian, Pérez, Santiago Hernández, Vincendeau, Estelle, Serrat, Judit, Thouin, Alexander Marc, Susvirkar, Vivek, Lescale, Chloé, Paniagua, Inés, Hoekman, Liesbeth, Kaur, Simranjeet, Altelaar, Maarten, Deriano, Ludovic, Faesen, Alex C, Jacobs, Jacqueline J L, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, 12(1). Nature Publishing Group
Nature Communications, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, 12(1). Nature Publishing Group
Nature Communications, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-25724-y⟩
MAD2L2 (REV7) plays an important role in DNA double-strand break repair. As a member of the shieldin complex, consisting of MAD2L2, SHLD1, SHLD2 and SHLD3, it controls DNA repair pathway choice by counteracting DNA end-resection. Here we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0eef28d1f10f82de63f851b152c960
https://hdl.handle.net/21.11116/0000-000A-7D73-921.11116/0000-000A-7D6F-F
https://hdl.handle.net/21.11116/0000-000A-7D73-921.11116/0000-000A-7D6F-F
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.15137. ⟨10.1038/s41598-020-71746-9⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.15137. ⟨10.1038/s41598-020-71746-9⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Glycosylation is a key modification that contributes to determine bioactivity and bioavailability of plant natural products, including that of terpenoids and steviol glycosides (SVglys). It is mediated by uridine-diphosphate glycosyltransferases (UGT
Autor:
Savva, Christos, Clark, Alice, Naylor, Claire, Popoff, Michel, Moss, David, Basak, Ajit, Titball, Richard, Bokori-Brown, Monika
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩
Nature Communications, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩
Nature Communications, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩
Epsilon toxin (Etx), a potent pore forming toxin (PFT) produced by Clostridium perfringens, is responsible for the pathogenesis of enterotoxaemia of ruminants and has been suggested to play a role in multiple sclerosis in humans. Etx is a member of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::03b5647c6160a8077e0ad0ee01cd113c
https://hal-pasteur.archives-ouvertes.fr/pasteur-02454060
https://hal-pasteur.archives-ouvertes.fr/pasteur-02454060
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.4710. ⟨10.1038/s41467-021-25064-x⟩
Nature Communications, 2021, 12 (1), pp.4710. ⟨10.1038/s41467-021-25064-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.4710. ⟨10.1038/s41467-021-25064-x⟩
Nature Communications, 2021, 12 (1), pp.4710. ⟨10.1038/s41467-021-25064-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Cyanophage S-2L is known to profoundly alter the biophysical properties of its DNA by replacing all adenines (A) with 2-aminoadenines (Z), which still pair with thymines but with a triple hydrogen bond. It was recently demonstrated that a homologue o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ba9188fcf7e481c569c2da53505c0af8
https://hal-pasteur.archives-ouvertes.fr/pasteur-03327945/file/s41467-021-25064-x.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03327945/file/s41467-021-25064-x.pdf
Autor:
Nani Van Gerven, Rick R. M. Joosten, Wai Li Ling, Alexander E. S. Van Driessche, Nico A. J. M. Sommerdijk, Mike Sleutel, Maria Bacia
Publikováno v:
Nature Communications
Nature Communications, 2021, 12, pp.3902. ⟨10.1038/s41467-021-24171-z⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-24171-z⟩
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-24171-z⟩
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications, 12
Nature Communications, 12, 1
Nature Communications, Nature Publishing Group, 2021, 12, pp.3902. ⟨10.1038/s41467-021-24171-z⟩
Nature Communications, 12(1):3902. Nature Publishing Group
Nature Communications, 2021, 12, pp.3902. ⟨10.1038/s41467-021-24171-z⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-24171-z⟩
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-24171-z⟩
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications, 12
Nature Communications, 12, 1
Nature Communications, Nature Publishing Group, 2021, 12, pp.3902. ⟨10.1038/s41467-021-24171-z⟩
Nature Communications, 12(1):3902. Nature Publishing Group
Self-assembly of proteins holds great promise for the bottom-up design and production of synthetic biomaterials. In conventional approaches, designer proteins are pre-programmed with specific recognition sites that drive the association process towar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d193043e542523da268f8ea4f42202
https://hal.univ-grenoble-alpes.fr/hal-03358785/file/alex1.pdf
https://hal.univ-grenoble-alpes.fr/hal-03358785/file/alex1.pdf
Autor:
N. Kyle Tanner, Mourad Barhoumi, Emna Harigua-Souiai, Arnaud Blondel, Josette Banroques, Yosser Zina Abdelkrim, Ikram Guizani
Publikováno v:
Molecular and Biochemical Parasitology
Molecular and Biochemical Parasitology, 2018, 226, pp.9-19. ⟨10.1016/j.molbiopara.2018.10.001⟩
Molecular and Biochemical Parasitology, Elsevier, 2018, 226, pp.9-19. ⟨10.1016/j.molbiopara.2018.10.001⟩
Molecular and Biochemical Parasitology, 2018, 226, pp.9-19. ⟨10.1016/j.molbiopara.2018.10.001⟩
Molecular and Biochemical Parasitology, Elsevier, 2018, 226, pp.9-19. ⟨10.1016/j.molbiopara.2018.10.001⟩
International audience; The antifungal agent 6-aminocholestanol targets the production of ergosterol, which is the principle sterol in many fungi and protozoans; ergosterol serves many of the same roles as cholesterol in animals. We found that it als
Autor:
Carlos Contreras-Martel, Leandro F. Estrozi, Daniel M. Trindade, Mayara M. Miyachiro, Fernanda Rodrigues-Costa, Ina Attrée, Guy Schoehn, Caíque C. Malospirito, Alexandre Martins, Viviana Job, Andréa Dessen, Lionel Imbert, Manon Janet-Maitre
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-22957-9⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2987. ⟨10.1038/s41467-021-22957-9⟩
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, 2021, 12 (1), pp.2987. ⟨10.1038/s41467-021-22957-9⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-22957-9⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2987. ⟨10.1038/s41467-021-22957-9⟩
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, 2021, 12 (1), pp.2987. ⟨10.1038/s41467-021-22957-9⟩
The elongasome, or Rod system, is a protein complex that controls cell wall formation in rod-shaped bacteria. MreC is a membrane-associated elongasome component that co-localizes with the cytoskeletal element MreB and regulates the activity of cell w