β-arrestin-1 participates in thrombosis and regulates integrin aIIbβ3 signalling without affecting P2Y receptors desensitisation and function

Autor: Schaff, Mathieu, Receveur, Nicolas, Bourdon, Catherine, Ohlmann, Philippe, Lanza, François, Gachet, Christian, Mangin, Pierre Henri

Publikováno v: Thrombosis and Haemostasis
Thrombosis and Haemostasis, Schattauer, 2012, 107 (4), pp.735-48. ⟨10.1160/TH11-06-0430⟩

International audience; β-arrestin-1 (β-arr1) and β-arrestin-2 (β-arr2) are cytosolic proteins well-known to participate in G protein-coupled receptor desensitisation and signalling. We used genetically-inactivated mice to evaluate the role of β

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::832ac253d7b7b6f1de3440c5426f248d
https://www.hal.inserm.fr/inserm-00678288/file/barr_2012.PDF

ATP signalling is crucial for the response of human keratinocytes to mechanical stimulation by hypo-osmotic shock

Autor: Nathalie, Azorin, Matthieu, Raoux, Lise, Rodat-Despoix, Thierry, Merrot, Patrick, Delmas, Marcel, Crest

Publikováno v: Experimental Dermatology
Experimental Dermatology, Wiley, 2011, 20 (5), pp.401-7. ⟨10.1111/j.1600-0625.2010.01219.x⟩
Experimental Dermatology, 2011, 20 (5), pp.401-7. ⟨10.1111/j.1600-0625.2010.01219.x⟩

International audience; Touch is detected through receptors located in the skin and the activation of channels in sensory nerve fibres. Epidermal keratinocytes themselves, however, may sense mechanical stimulus and contribute to skin sensation. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7cff38a8755304668dd2f5ef39ef2f0b
https://hal.archives-ouvertes.fr/hal-00625485