Cell surface adenylate kinase activity regulates the F1-ATPase/P2Y13-mediated HDL endocytosis pathway on human hepatocytes

Autor: Laurent O. Martinez, Bertrand Perret, François Tercé, Pierre Vantourout, Xavier Collet, Aurélie C.S. Fabre, Corinne Rolland, Eric Champagne, Ronald Barbaras

Publikováno v: Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, 2006, 63 (23), pp.2829-37. ⟨10.1007/s00018-006-6325-y⟩
Cellular and Molecular Life Sciences, Springer Verlag, 2006, 63 (23), pp.2829-37. ⟨10.1007/s00018-006-6325-y⟩

International audience; We have previously demonstrated on human hepatocytes that apolipoprotein A-I binding to an ecto-F(1)-ATPase stimulates the production of extracellular ADP that activates a P2Y(13)-mediated high-density lipoprotein (HDL) endocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b0f60bff415bacdfaa22ace498fe99
https://doi.org/10.1007/s00018-006-6325-y

Chronic pharmacological activation of P2Y13 receptor in mice decreases HDL-cholesterol level by increasing hepatic HDL uptake and bile acid secretion

Autor: Laeticia Lichtenstein, Nicole Malet, Bertrand Perret, Nizar Serhan, Céline Verdier, Cendrine Cabou, Muriel Laffargue, Laurent O. Martinez

Publikováno v: BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, 2013, 1831 (4), pp.719-25. ⟨10.1016/j.bbalip.2012.12.006⟩
BBA-Biochimica et Biophysica Acta, Elsevier, 2013, 1831 (4), pp.719-25. ⟨10.1016/j.bbalip.2012.12.006⟩

International audience; High level of high-density lipoprotein cholesterol (HDL-cholesterol) is inversely correlated to the risk of atherosclerotic cardiovascular disease. The protective effect of HDL is mostly attributed to their metabolic functions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334d88c163ce55a4d49a5afc35df17c1
https://doi.org/10.1016/j.bbalip.2012.12.006

Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration

Autor: Véronique Hofman, Paul Hofman, Valérie Vouret-Craviari, Bernard Ferrua, Robert J. Unwin, Patrick Brest, Franck Galland, Sandrine Marchetti, Annabelle Cesaro, Baharia Mograbi, Philippe Naquet, Scott S.P. Wildman, Alain Doglio, Xavier Hébuterne

Publikováno v: AJP-Gastrointestinal and Liver Physiology
AJP-Gastrointestinal and Liver Physiology, 2010, 299 (1), pp.G32-42. ⟨10.1152/ajpgi.00282.2009⟩
AJP-Gastrointestinal and Liver Physiology, American Physiological Society, 2010, 299 (1), pp.G32-42. ⟨10.1152/ajpgi.00282.2009⟩

Inflammatory bowel diseases (IBD) are characterized during their active phase by polymorphonuclear leukocyte (PMNL) transepithelial migration. The efflux of PMNL into the mucosa is associated with the production of proinflammatory cytokines and the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0872b9e1d7cab7f45ce0fb7fa6ff5d
https://hal.science/hal-00553099

Mycobacterium tuberculosis co-existence with humans: making an imprint on the macrophage P2X(7) receptor gene?

Autor: Igor Mokrousov, Nadezhda Sapozhnikova, Olga Narvskaya

Publikováno v: Journal of Medical Microbiology
Journal of Medical Microbiology, Society for General Microbiology, 2008, 57 (Pt 5), pp.581-4. ⟨10.1099/jmm.0.47455-0⟩

The development of tuberculosis (TB) infection in humans depends on the mycobacterial strain and the human host, and is multigenically controlled in both. ATP ligation of P2X7receptors expressed on human macrophages infected with mycobacteria induces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf69a3c205e6f87b65008639836849c9
https://pubmed.ncbi.nlm.nih.gov/18436590

Sequential shrinkage and swelling underlie P2X7-stimulated lymphocyte phosphatidylserine exposure and death

Autor: James I. Elliott, Mireya Gonzalez-Begne, Stephen Taylor, Christopher F. Higgins, Giovanna Chimini, Stephen Dewhurst, James E. Melvin

Publikováno v: Journal of Immunology
Journal of Immunology, 2008, 180 (1), pp.300-8
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 180 (1), pp.300-8

Patterns of change in cell volume and plasma membrane phospholipid distribution during cell death are regarded as diagnostic means of distinguishing apoptosis from necrosis, the former being associated with cell shrinkage and early phosphatidylserine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e12ba3aba01ceccc5a1fc1a495d1a39
https://hal.science/hal-00294279