Výsledky vyhledávání - "MESH: Receptors, Nerve Growth Factor"

Lobular architecture of human adipose tissue defines the niche and fate of progenitor cells

Autor: Christian Dani, A. Remaury, Jean Galitzky, Y. Veeranagouda, A. Briot, Anne Bouloumié, David Estève, M. Didier, Pauline Decaunes, Séverine Ledoux, Nathalie Boulet, Alexia Zakaroff-Girard, C. Belles, Jean-Claude Guillemot

Publikováno v: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, 2019, 10 (1), pp.2549. ⟨10.1038/s41467-019-09992-3⟩

Human adipose tissue (hAT) is constituted of structural units termed lobules, the organization of which remains to be defined. Here we report that lobules are composed of two extracellular matrix compartments, i.e., septa and stroma, delineating nich

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ccf7615a59410e938ba07ee13d46fc
http://europepmc.org/articles/PMC6560121

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Modeling amyotrophic lateral sclerosis in pure human iPSc-derived motor neurons isolated by a novel FACS double selection technique

Autor: Dorothée Buttigieg, Stéphane Blanchard, Diana Toli, Delphine Bohl, Georg Haase, Gilbert Baillat, Sarah Bellouze, Thomas Lemonnier, Boris Lamotte d'Incamps

Publikováno v: Neurobiology of Disease, Vol 82, Iss, Pp 269-280 (2015)
Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2015, 82, pp.269-280. ⟨10.1016/j.nbd.2015.06.011⟩
Neurobiology of Disease, 2015, 82, pp.269-280. ⟨10.1016/j.nbd.2015.06.011⟩

International audience; Amyotrophic lateral sclerosis (ALS) is a severe and incurable neurodegenerative disease. Human motor neurons generated from induced pluripotent stem cells (iPSc) offer new perspectives for disease modeling and drug testing in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c65ffa44a284ec8da4026ffb27e4be6
https://doi.org/10.1016/j.nbd.2015.06.011

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Regulatory T-cell expansion and function do not account for the impaired alloreactivity ofex vivo-expanded T cells

Autor: Eric Robinet, Mélanie Couturier, Christophe Ferrand, Nicolas Montcuquet, Patricia Mercier-Letondal, Sylvain Perruche, Abdelghani Bouchekioua, Pierre Tiberghien, Anne Duperrier, Mark Bonyhadi

Publikováno v: Immunology
Immunology, Wiley, 2008, 125 (3), pp.320-30. ⟨10.1111/j.1365-2567.2008.02843.x⟩

International audience; CD3- and CD28-activated T cells expanded for 12 days ex vivo to produce suicide gene-modified T cells are hyporesponsive to alloantigens. To investigate whether this impaired alloreactivity is a result of preferential expansio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e36bf5594c259a026350d6fa8da2af9
https://doi.org/10.1111/j.1365-2567.2008.02843.x

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Fine-Tuning Roles of Endogenous Brain-Derived Neurotrophic Factor, TrkB and Sortilin in Colorectal Cancer Cell Survival

Autor: Hussein Akil, Marie-Odile Jauberteau, Carole Mélin, Muriel Mathonnet, Aurélie Perraud

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (9), pp.e25097. ⟨10.1371/journal.pone.0025097⟩
PLoS ONE, Public Library of Science, 2011, 6 (9), pp.e25097. 〈10.1371/journal.pone.0025097〉
PLoS ONE, Vol 6, Iss 9, p e25097 (2011)

International audience; BACKGROUND: Neurotrophin receptors were initially identified in neural cells. They were recently detected in some cancers in association with invasiveness, but the function of these tyrosine kinase receptors was not previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d43b76bf780c6d3c2bff39a16d0edd
https://hal.archives-ouvertes.fr/hal-02427316

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The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo

Autor: Sabine Scarzello, Charlotte Druon, Claire Sunyach, Frédéric Checler, Marie-Victoire Guillot-Sestier

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (51), pp.35973-86. ⟨10.1074/jbc.M109.051086⟩

International audience; Cellular prion protein (PrP(c)) undergoes a disintegrin-mediated physiological cleavage, generating a soluble amino-terminal fragment (N1), the function of which remained unknown. Recombinant N1 inhibits staurosporine-induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d094d9b28dec1225a1c8cbc32d97b7ed
https://hal.archives-ouvertes.fr/hal-00497181

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Functional interaction between p75NTR and TrkA: the endocytic trafficking of p75NTR is driven by TrkA and regulates TrkA-mediated signalling

Autor: Lorena Perrone, Chiara Zurzolo, Lucio Nitsch, Simona Paladino, Massimo Gulisano, Marialuisa Mazzone

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2005, 385 (Pt 1), pp.233-41. ⟨10.1042/BJ20041155⟩
Biochemical Journal, 2005, 385 (Pt 1), pp.233-41. ⟨10.1042/BJ20041155⟩

The topology and trafficking of receptors play a key role in their signalling capability. Indeed, receptor function is related to the microenvironment inside the cell, where specific signalling molecules are compartmentalized. The response to NGF (ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ba78084076224d49194c754f5ede84
https://hal-pasteur.archives-ouvertes.fr/pasteur-00167022

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Opposing roles for neurotrophin-3 in targeting and collateral formation of distinct sets of developing cortical neurons

Autor: Jürgen Bolz, Valérie Castellani

Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 1999, 126 (15), pp.3335-45
ResearcherID

Neurotrophin-3 and its receptor TrkC are expressed during the development of the mammalian cerebral cortex. To examine whether neurotrophin-3 might play a role in the elaboration of layer-specific cortical circuits, slices of layer 6 and layers 2/3 n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2258a25b265ceb7f39efc8bbc40991ca
https://pubmed.ncbi.nlm.nih.gov/10393113

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Expression of mRNAs encoding BDNF and its receptor in adult rat hypothalamus

Autor: Frédéeric Marmigere, Sandor Arancibia, Lucia Tapia-Arancibia, Florence Rage

Publikováno v: Scopus-Elsevier
NeuroReport
NeuroReport, Lippincott, Williams & Wilkins, 1998, 9 (6), pp.1159-1163. ⟨10.1097/00001756-199804200-00037⟩

International audience; We used a digoxigenin-UTP-labeled cRNA probe with in situ hybridization and Northern blot analysis to investigate the localization of brain derived neurotrophic factor (BDNF) mRNA and expression of its different transcripts in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b46695721d789b0c3a76d1a5ef85f3
http://www.scopus.com/inward/record.url?eid=2-s2.0-0032550108&partnerID=MN8TOARS

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