Leukotriene BLT2 receptor monomers activate the G(i2) GTP-binding protein more efficiently than dimers.: G protein activation by monomeric and dimeric GPCRs

Autor: Corinne Vivès, Jean-Louis Banères, Gérald Gaibelet, Emilie Detouillon, Thierry Durroux, Christiane Mendre, Laure Arcemisbéhère, Sébastien Granier, Marie-Noëlle Balestre, Tuhinadri Sen, Hélène Orcel, Franck Fieschi, Laure Boudier, Bernard Mouillac, Marjorie Damian, Rita Rahmeh

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2010, 285 (9), pp.6337-47. ⟨10.1074/jbc.M109.083477⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (9), pp.6337-47. ⟨10.1074/jbc.M109.083477⟩

International audience; Accumulating evidence indicates that G protein-coupled receptors can assemble as dimers/oligomers but the role of this phenomenon in G protein coupling and signaling is not yet clear. We have used the purified leukotriene B(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d3f13fc9d6ad1a72087358890dbf09
https://www.hal.inserm.fr/inserm-00457594/file/inserm-00457594_edited.pdf

Leukotriene BLT2 receptor monomers activate the G(i2) GTP-binding protein more efficiently than dimers

Autor: Arcemisbehere, Laure, Sen, Tuhinadri, Boudier, Laure, Balestre, Marie-Noëlle, Gaibelet, Gérald, Detouillon, Emilie, Orcel, Hélène, Mendre, Christiane, Rahmeh, Rita, Granier, Sébastien, Vivès, Corinne, Fieschi, Franck, Damian, Marjorie, Durroux, Thierry, Baneres, Jean-Louis, Mouillac, Bernard

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2010, 285 (9), pp.6337-47. ⟨10.1074/jbc.M109.083477⟩

International audience; Accumulating evidence indicates that G protein-coupled receptors can assemble as dimers/oligomers but the role of this phenomenon in G protein coupling and signaling is not yet clear. We have used the purified leukotriene B(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::511ca5439e12e79016d5b3b5d3543db4
https://doi.org/10.1074/jbc.M109.083477

New tensio-active molecules stabilize a human G protein-coupled receptor in solution

Autor: Aimée Martin, Ange Polidori, Marjorie Damian, Sandrine Perino, Bernard Pucci, Laurence Serre, Jean-Louis Banères

Publikováno v: FEBS Letters
FEBS Letters, Wiley, 2007, 581 (10), pp.1944-50. ⟨10.1016/j.febslet.2007.03.091⟩
FEBS Letters, 2007, 581 (10), pp.1944-50. ⟨10.1016/j.febslet.2007.03.091⟩

International audience; Structural characterization of membrane proteins is hampered by the instability of the isolated proteins in detergent solutions. Here, we describe a new class of phospholipid-like surfactants that stabilize the G protein-coupl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da975a2fd19b06f3b133d167312c1556
https://pubmed.ncbi.nlm.nih.gov/17445804