ACE inhibitor reduces growth factor receptor expression and signaling but also albuminuria through B2-kinin glomerular receptor activation in diabetic rats

Autor: Françoise Praddaude, Christiane Pecher, Julien Allard, Isabelle Renaud, Marie Buléon, Eric Cellier, Jean-Pierre Girolami, Ivan Tack, Marc Conti

Publikováno v: AJP Renal Physiology
AJP Renal Physiology, American Physiological Society, 2007, 293 (4), pp.F1083-92. ⟨10.1152/ajprenal.00401.2006⟩
AJP Renal Physiology, 2007, 293 (4), pp.F1083-92. ⟨10.1152/ajprenal.00401.2006⟩

International audience; Diabetic nephropathy (DN) is associated with increased oxidative stress, overexpression and activation of growth factor receptors, including those for transforming growth factor-beta1 (TGF-beta-RII), platelet-derived growth fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d14d320219be744c09e39289363d0f
https://doi.org/10.1152/ajprenal.00401.2006

Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays

Autor: Bernard Klein, Tobias Meißner, Jérôme Moreaux, Hartmut Goldschmidt, Dirk Hose, Karène Mahtouk, Thierry Rème, Jean François Rossi, Michel Jourdan, Steven T. Pals

Publikováno v: BMC Cancer
BMC Cancer, 10(1). BioMed Central
BMC Cancer, BioMed Central, 2010, 10 (1), pp.198. ⟨10.1186/1471-2407-10-198⟩
BMC cancer, 10(1). BioMed Central
BMC Cancer, Vol 10, Iss 1, p 198 (2010)

Background Multiple myeloma (MM) is characterized by a strong dependence of the tumor cells on their microenvironment, which produces growth factors supporting survival and proliferation of myeloma cells (MMC). In the past few years, many myeloma gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e81db216f6a44c4843111ab1dbc67e
https://pubmed.ncbi.nlm.nih.gov/20465808

Paracrine and Autocrine Signals Promoting Full Chondrogenic Differentiation of a Mesoblastic Cell Line

Autor: Michel Huerre, Odile Kellermann, Marie Boucquey, Huot Khun, Morgane Locker, Anne Poliard

Publikováno v: Journal of Bone and Mineral Research
Journal of Bone and Mineral Research, 2004, 19 (1), pp.100-110. ⟨10.1359/JBMR.0301206⟩
Journal of Bone and Mineral Research, American Society for Bone and Mineral Research, 2004, 19 (1), pp.100-110. ⟨10.1359/JBMR.0301206⟩

The pluripotent mesoblastic C1 cell line was used under serum-free culture conditions to investigate how paracrine and autocrine signals cooperate to drive chondrogenesis. Sequential addition of two systemic hormones, dexamethasone and triiodothyroni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f7933411a432269dc34bbe45aebe08
https://hal.science/hal-03297141

No evidence for linkage or for diabetes-associated mutations in the activin type 2B receptor gene (ACVR2B) in French patients with mature-onset diabetes of the young or type 2 diabetes

Autor: Corentin Cras-Méneur, Sophie Dupont, Cécile Lecoeur, Raphael Scharfmann, El Habib Hani, Frédérique De Matos, Martine Vaxillaire, Philippe Froguel, Stéphane Lobbens

Publikováno v: Diabetes
Diabetes, American Diabetes Association, 2001, 50 (5), pp.1219-21

Activins are members of the transforming growth factor-β superfamily. They have a wide range of biological effects on cell growth and differentiation. For transmembrane signaling, activins bind directly to activin receptor type 2A (ACVR2A) or 2B (AC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3c7bb287251f016b0e9683d72d97c1
https://hal.archives-ouvertes.fr/hal-00174786