Výsledky vyhledávání - "MESH: Rats, Inbred SHR"

Contribution of serotonin to cardiac remodeling associated with hypertensive diastolic ventricular dysfunction in rats

Autor: Rachel L Matz, Marie-France Champy, Laurent Monassier, Roland Lawson, Roy Combe, Katia Boutourlinsky, Walid Mokni, Julien Becker, Lahcen El Fertak, Halim Marzak, Ramaroson Andriantsitohaina, Olivia Wendling, Estelle Ayme-Dietrich, Stéphane Doly, Luc Maroteaux

Publikováno v: Journal of Hypertension
Journal of Hypertension, Lippincott, Williams & Wilkins, 2015, 33, pp.2310-2321
Journal of Hypertension, 2015, 33 (11), pp.2310-2321. ⟨10.1097/HJH.0000000000000695⟩
Journal of Hypertension, Lippincott, Williams & Wilkins, 2015, 33 (11), pp.2310-2321. ⟨10.1097/HJH.0000000000000695⟩
Journal of Hypertension, Lippincott, Williams & Wilkins, 2015, 33 (11), pp.2310-2321. 〈10.1097/HJH.0000000000000695〉

Objective: Left-ventricular hypertrophy and interstitial fibrosis are the main pathophysiological factors of heart failure with preserved ejection fraction. Blockade of the serotonin 5-HT 2B receptor (5-HT 2B R) has been shown to reduce cardiac hyper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb41b81e6c0de9b8230e23ceedf8e748
https://hal.archives-ouvertes.fr/hal-01280414

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Assessment of the early stage of cardiac remodeling of spontaneously hypertensive heart failure rats using the quantitative 3-dimensional analysis provided by acipimox-enhanced FDG-PET

Autor: Patrick Lacolley, Mickael Lhuillier, Pierre Y. Marie, Huguette Louis, S. Poussier, Henri Boutley, Gilles Karcher, Simon N. Thornton, Fatiha Maskali

Publikováno v: International Journal of Cardiovascular Imaging
International Journal of Cardiovascular Imaging, Springer Verlag, 2014, 30 (2), pp.449-456. ⟨10.1007/s10554-013-0350-3⟩

International audience; Spontaneously hypertensive heart failure rats (SHHF) appear to constitute an original model for analyzing the evolution of the metabolic syndrome towards heart failure. This study aimed to characterize early cardiac dysfunctio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13697aab31f0593efed158ce3435657f
https://hal.univ-lorraine.fr/hal-01738436

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Treatment with the arginase inhibitor N(omega)-hydroxy-nor-L-arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat

Autor: Alain Berthelot, Céline Demougeot, Pascal Laurant, Yves Claude Guillaume, Claire André, Malika Bouhaddi, Teddy Bagnost

Publikováno v: Journal of Hypertension
Journal of Hypertension, Lippincott, Williams & Wilkins, 2008, 26 (6), pp.1110-8. ⟨10.1097/HJH.0b013e3282fcc357⟩
Journal of Hypertension, Lippincott, Williams & Wilkins, 2008, 26 (6), pp.1110-8. 〈10.1097/HJH.0b013e3282fcc357〉

International audience; OBJECTIVE: High vascular arginase activity and subsequent reduction in vascular nitric oxide production were recently reported in animal models of hypertension. The present study investigated the effects of in-vivo arginase in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe51de70b63a3cb987be8fdd7ef63ae
https://hal.archives-ouvertes.fr/hal-00452097

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Time course of vascular arginase expression and activity in spontaneously hypertensive rats

Autor: Christine Marie, Teddy Bagnost, Alain Berthelot, Céline Demougeot, Malika Bouhaddi, Yves Claude Guillaume, Claire André, Anne Prigent-Tessier

Publikováno v: Life Sciences
Life Sciences, Elsevier, 2007, 80 (12), pp.1128-1134. ⟨10.1016/j.lfs.2006.12.003⟩
Life Sciences, Elsevier, 2007, 80 (12), pp.1128-1134. 〈10.1016/j.lfs.2006.12.003〉

International audience; There is growing evidence that vascular arginase plays a role in pathophysiology of vascular diseases. We recently reported high arginase activity/expression in young adult hypertensive spontaneously hypertensive rats (SHR). T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d8a231d316532050ef6361834fd30c
https://pubmed.ncbi.nlm.nih.gov/17223136

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A New Pyrroline Compound Selective for I1-Imidazoline Receptors Improves Metabolic Syndrome in Rats

Autor: Lyne Fellmann, Véronique Regnault, Nathalie Niederhoffer, Bruno Fève, Pascal Bousquet, A. Muscat, Vincent Gasparik, Anne Pizard, Jean-Pierre Max, Luc Gigou, Claude Julien, Hugues Greney, Patrick Lacolley, Gérard S. Chetrite, Valérie Oréa

Publikováno v: Journal of Pharmacology and Experimental Therapeutics
Journal of Pharmacology and Experimental Therapeutics, 2013, 346 (3), pp.370-380. ⟨10.1124/jpet.113.205328⟩
Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2013, 346 (3), pp.370-380. ⟨10.1124/jpet.113.205328⟩

International audience; Symptoms of the metabolic syndrome (MetS), such as insulin resistance, obesity, and hypertension, have been associated with sympathetic hyperactivity. In addition, the adiponectin pathway has interesting therapeutic potentials

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13740cb84cfe9c024d47aa8aa1ec8dc0
https://hal.univ-lorraine.fr/hal-01737409

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Regulatory function of a malleable protein matrix as a novel fermented whey product on features defining the metabolic syndrome

Autor: E. Millette, Claude Dupont, Josée Beaulieu, E. Trottier, L.-P. Précourt, P. Lemieux

Publikováno v: Journal of Medicinal Food
Journal of Medicinal Food, Mary Ann Liebert, 2010, 13 (3), pp.509-19. ⟨10.1089/jmf.2009.0083⟩

Previously, we reported that a malleable protein matrix (MPM), composed of whey fermented by a proprietary Lactobacillus kefiranofaciens strain, has immunomodulatory and anti-inflammatory properties. MPM consumption leads to a considerable reduction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe658d37d73b665c865645b8cc297e7f
https://hal-riip.archives-ouvertes.fr/pasteur-00819608

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Misregulation of the arginase pathway in tissues of spontaneously hypertensive rats

Autor: Carole Miguet-Alfonsi, Teddy Bagnost, Yves Claude Guillaume, Claire André, Magalie Alvergnas, Alain Berthelot, Céline Demougeot

Publikováno v: Hypertension Research
Hypertension Research, Nature Publishing Group, 2009, 32 (12), pp.1130-1135. ⟨10.1038/hr.2009.153⟩

International audience; There is a growing evidence that arginase has a role in the pathophysiology of cardiovascular diseases including hypertension. We recently reported arginase upregulation in aortas from hypertensive spontaneously hypertensive r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d1dd980fd6867cac311970de745224
https://hal.archives-ouvertes.fr/hal-00486348

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Arginase inhibition reduces endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats

Autor: Alain Berthelot, Céline Demougeot, Christine Marie, Anne Prigent-Tessier

Publikováno v: Journal of Hypertension
Journal of Hypertension, Lippincott, Williams & Wilkins, 2005, 23 (5), pp.971-978
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International audience; OBJECTIVE: A decrease in nitric oxide (NO) bioavailability has been proposed to contribute to endothelial dysfunction and increased peripheral resistances during essential arterial hypertension. Given that arginine is a substr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369f393bf04fae17060cbaa269ea1d07
https://hal.archives-ouvertes.fr/hal-00499466

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High blood pressure reduction reverses angiotensin II type 2 receptor-mediated vasoconstriction into vasodilation in spontaneously hypertensive rats.: AT2 receptor function in hypertension

Autor: You, Dong, Loufrani, Laurent, Baron, Céline, Levy, Bernard, Widdop, Robert, Henrion, Daniel

Publikováno v: Circulation
Circulation, 2005, 111 (8), pp.1006-11. ⟨10.1161/01.CIR.0000156503.62815.48⟩

International audience; BACKGROUND: We have previously shown that angiotensin II type 2 receptor (AT(2)R) stimulation causes endothelium-dependent vasodilation that does not desensitize after chronic angiotensin II type 1 receptor (AT1R) blockade, su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::5637611c6829f459737be4af0bf59211
https://www.hal.inserm.fr/inserm-00134941

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High blood pressure reduction reverses angiotensin II type 2 receptor-mediated vasoconstriction into vasodilation in spontaneously hypertensive rats

Autor: You, Dong, Loufrani, Laurent, Baron, Céline, Levy, Bernard, Widdop, Robert, Henrion, Daniel

Publikováno v: Circulation
Circulation, American Heart Association, 2005, 111 (8), pp.1006-11. ⟨10.1161/01.CIR.0000156503.62815.48⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5637611c6829f459737be4af0bf59211
https://www.hal.inserm.fr/inserm-00134941

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