Zobrazeno 1 - 10 of 71 pro vyhledávání: '"MESH: Random Allocation"'
1
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption
Autor: Maureen J O'Meara, Daniel J. O’Connell, Cheng-Chia Tang, Avner Schlessinger, Marc Foretz, Janaina S. Martins, Peter Man-Un Ung, Paul Roschger, Rebecca Berdeaux, Nathanael S. Gray, Clifford J. Rosen, Tadatoshi Sato, Daniel J. Brooks, Ramnik J. Xavier, Thomas B. Sundberg, Henry M. Kronenberg, Yosta Vegting, Mary L. Bouxsein, Barbara M. Misof, Sung-Hee Yoon, Jinhua Wang, Marc N. Wein, Annegreet Velduis-Vlug, Christian D. Castro Andrade, Klaus Klaushofer, Stéphane Blouin
Publikováno v: eLife
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.67772⟩
eLife, 10:e67772. eLife Sciences Publications
eLife, Vol 10 (2021)
Bone formation and resorption are typically coupled, such that the efficacy of anabolic osteoporosis treatments may be limited by bone destruction. The multi-kinase inhibitor YKL-05-099 potently inhibits salt inducible kinases (SIKs) and may represen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2cd72b852d7bf7519a5a1896c7ff70
http://europepmc.org/articles/PMC8238509
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2
Non-targeted metabolomics analyses by mass spectrometry to explore metabolic stress after six training weeks in high level swimmers
Autor: Delphine Centeno, Marion Brandolini-Bunlon, Stéphanie Durand, Jean-François Toussaint, Estelle Pujos-Guillot, Robin Pla, David B. Pyne, Philippe Hellard
Publikováno v: Journal of Sports Sciences
Journal of Sports Sciences, Taylor & Francis, 2021, 39 (9), pp.969-978. ⟨10.1080/02640414.2020.1851933⟩
Journal of Sports Sciences, Taylor & Francis: SSH Journals, 2020, pp.1-10. ⟨10.1080/02640414.2020.1851933⟩
Journal of Sports Sciences, 2021, 39 (9), pp.969-978. ⟨10.1080/02640414.2020.1851933⟩
Journal of Sports Sciences, Taylor & Francis: SSH Journals, 2021, 39 (9), pp.969-978. ⟨10.1080/02640414.2020.1851933⟩
International audience; The objective was to compare the metabolic responses of high-level national swimmers to threshold or polarised training. 22 swimmers (n = 12 males and 10 females) participated in a 28-week cross-over intervention study consist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809de7a860d431a235a1164f99406ef5
https://hal.inrae.fr/hal-03275295
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3
Morphine withdrawal recruits lateral habenula cytokine signaling to reduce synaptic excitation and sociability
Autor: Camilla Bellone, Arnaud L. Lalive, Kristina Valentinova, Manuel Mameli, Imane Moutkine, Anna Tchenio, Massimo Trusel, Luc Maroteaux, Andrea Volterra, Joseph A. Clerke, Alessandro Matera, Stamatina Tzanoulinou, Rosa C. Paolicelli
Publikováno v: Nature neuroscience, vol. 22, no. 7, pp. 1053-1056
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2019, 22 (7), pp.1053-1056. ⟨10.1038/s41593-019-0421-4⟩
Nature Neuroscience, Vol. 22, No 7 (2019) pp. 1053-1056
International audience; The lateral habenula encodes aversive stimuli contributing to negative emotional states during drug withdrawal. Here we report that morphine withdrawal in mice leads to microglia adaptations and diminishes glutamatergic transm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da6543952922e61243c3e80527d4673
https://pubmed.ncbi.nlm.nih.gov/31209376
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4
Assessment on Experimental Bacterial Biofilms and in Clinical Practice of the Efficacy of Sampling Solutions for Microbiological Testing of Endoscopes
Autor: Claire Hennequin, E. Thibert, Ousmane Traore, F. A. Chapelle, Olivier Lesens, Claire Aumeran
Publikováno v: Journal of Clinical Microbiology
Journal of Clinical Microbiology, American Society for Microbiology, 2012, 50 (3), pp.938-42. ⟨10.1128/JCM.06221-11⟩
Journal of Clinical Microbiology, 2012, 50 (3), pp.938-42. ⟨10.1128/JCM.06221-11⟩
Opinions differ on the value of microbiological testing of endoscopes, which varies according to the technique used. We compared the efficacy on bacterial biofilms of sampling solutions used for the surveillance of the contamination of endoscope chan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6abbc656552fccda97a715950c9ce8
https://doi.org/10.1128/jcm.06221-11
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5
Cognitive processing impairments in a supra-second temporal discrimination task in rats with cerebellar lesion
Autor: Bruce L. Brown, Delphine Callu, Valérie Doyère, Gérard Dutrieux, Nicole El Massioui
Publikováno v: Neurobiology of Learning and Memory
Neurobiology of Learning and Memory, Elsevier, 2009, 91 (3), pp.250-9. ⟨10.1016/j.nlm.2008.12.002⟩
International audience; The role of interpositus nuclei (IN) in timing in the sub-second range is well supported in eyeblink conditioning studies. Timing impairments shown in the seconds range in patients with intermediate cerebellar lesion, and know
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79283f300ea37ed4c24b0e5c8a2d9ae1
https://doi.org/10.1016/j.nlm.2008.12.002
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6
Transmission of pathogenic respiratory bacteria to specific pathogen free pigs at slaughter
Autor: Corinne Marois, Roland Cariolet, Hervé Morvan, Marylène Kobisch
Publikováno v: Veterinary Microbiology
Veterinary Microbiology, Elsevier, 2008, 129 (3-4), pp.325-32. ⟨10.1016/j.vetmic.2007.11.030⟩
Veterinary Microbiology, Elsevier, 2008, 129 (3-4), pp.325. ⟨10.1016/j.vetmic.2007.11.030⟩
8 pages; International audience; The purpose of this study was to evaluate the transmission of pathogenic respiratory bacteria to thirteen 5-month-old specific pathogen free (SPF) pigs, during the slaughtering process in a commercial slaughterhouse.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b88ee0306e2db5ffa32c91bce4c5685
https://doi.org/10.1016/j.vetmic.2007.11.030
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7
Effect of training frequency on endothelium-dependent vasorelaxation in rats
Autor: Jacques Mansourati, Michael Theron, François Guerrero, E. Heylen, B. Saïag, Sanéo Thioub
Publikováno v: European Journal of Cardiovascular Prevention and Rehabilitation
European Journal of Cardiovascular Prevention and Rehabilitation, SAGE Publications, 2008, 15 (1), pp.52-8. ⟨10.1097/HJR.0b013e3282f17baa⟩
International audience; BACKGROUND: Moderate physical activity enhances endothelium-dependent vasorelaxation. Whether the frequency of exercise affects endothelial function is unclear. The purpose of this study was to investigate the effects of vario
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8ffb3d18977993f84938fb8fba5b07
https://doi.org/10.1097/hjr.0b013e3282f17baa
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8
ACE inhibitor reduces growth factor receptor expression and signaling but also albuminuria through B2-kinin glomerular receptor activation in diabetic rats
Autor: Françoise Praddaude, Christiane Pecher, Julien Allard, Isabelle Renaud, Marie Buléon, Eric Cellier, Jean-Pierre Girolami, Ivan Tack, Marc Conti
Publikováno v: AJP Renal Physiology
AJP Renal Physiology, American Physiological Society, 2007, 293 (4), pp.F1083-92. ⟨10.1152/ajprenal.00401.2006⟩
AJP Renal Physiology, 2007, 293 (4), pp.F1083-92. ⟨10.1152/ajprenal.00401.2006⟩
International audience; Diabetic nephropathy (DN) is associated with increased oxidative stress, overexpression and activation of growth factor receptors, including those for transforming growth factor-beta1 (TGF-beta-RII), platelet-derived growth fa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d14d320219be744c09e39289363d0f
https://doi.org/10.1152/ajprenal.00401.2006
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9
Impact of fish oils on the outcomes of a mouse model of acute Pseudomonas aeruginosa pulmonary infection
Autor: Luce Sergent, Frédéric Gottrand, Emilie Caron, Alain Duhamel, Nana Bartke, Marie-Odile Husson, Jean-Luc Desseyn
Publikováno v: British Journal of Nutrition
British Journal of Nutrition, Cambridge University Press (CUP), 2015, 113 (2), pp.191-199. ⟨10.1017/S0007114514003705⟩
British Journal of Nutrition, 2015, 113 (2), pp.191-199. ⟨10.1017/S0007114514003705⟩
Pseudomonas aeruginosais an opportunistic Gram-negative bacterium that causes pneumonia in immunocompromised humans and severe pulmonary damage in patients with cystic fibrosis. Imbalanced fatty acid incorporation in membranes, including increased ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ee35b29f68aafc7150d4efdafbc1c4
https://hal.univ-lille.fr/hal-02178806/file/Caron2015BJNutr.pdf
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10
Clinical outcomes according to QRS duration and morphology in the Eplerenone in Mild Patients: Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF)
Autor: Jane A, Cannon, Timothy J, Collier, Li, Shen, Karl, Swedberg, Henry, Krum, Dirk J, Van Veldhuisen, John, Vincent, Stuart J, Pocock, Bertram, Pitt, Faiez, Zannad, John J V, McMurray
Publikováno v: European Journal of Heart Failure, 17(7), 707-716. Wiley
European Journal of Heart Failure
European Journal of Heart Failure, Oxford University Press (OUP), 2015, 17 (7), pp.707-716. ⟨10.1002/ejhf.303⟩
International audience; AIMS:We examined the relationship between different degrees of QRS prolongation and different QRS morphologies and clinical outcomes in patients with heart failure, reduced ejection fraction (HF-REF), and mild symptoms in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8131225780df7711e7d232d7cf07c5ee
https://acuresearchbank.acu.edu.au/item/88q4v/clinical-outcomes-according-to-qrs-duration-and-morphology-in-the-eplerenone-in-mild-patients-hospitalization-and-survival-study-in-heart-failure-emphasis-hf
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