Zobrazeno 1 - 10
of 17
pro vyhledávání: '"MESH: RNA-Directed DNA Polymerase"'
Autor:
Mohcine Elmessaoudi-Idrissi, Arnaud Blondel, Anass Kettani, Marc P. Windisch, Sayeh Ezzikouri, Soumaya Benjelloun
Publikováno v:
Current Medicinal Chemistry
Current Medicinal Chemistry, Bentham Science Publishers, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Current Medicinal Chemistry, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Current Medicinal Chemistry, Bentham Science Publishers, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Current Medicinal Chemistry, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Hepatitis B Virus (HBV) is a major global health burden. Interferon alpha and nucleos(t)ide analogues are currently the standard-of-care for chronic HBV infection. However, these antiviral agents have limited efficacy and do not result in a sustained
Autor:
Marcelle Wilhelm, F.X. Wilhelm
Publikováno v:
Eukaryotic Cell
Eukaryotic Cell, American Society for Microbiology, 2006, 5 (10), pp.1760-9. ⟨10.1128/EC.00159-06⟩
Eukaryotic Cell, American Society for Microbiology, 2006, 5 (10), pp.1760-9. ⟨10.1128/EC.00159-06⟩
Reverse transcriptase (RT) and integrase (IN) play a central role in the replication and transposition of retroelements. Increasing evidence suggests that the interaction between these two enzymes is functional and plays an important role in replicat
Autor:
Martinez, Miguel Angel, Sala, Monica, Vartanian, Jean Pierre, Wain-Hobson, S, Wain-Hoboson, Simon
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 1995, 23 (14), pp.2573-2578. ⟨10.1093/nar/23.14.2573⟩
Nucleic Acids Research, 1995, 23 (14), pp.2573-2578. ⟨10.1093/nar/23.14.2573⟩
International audience; G-->A hypermutation is a remarkable phenomenon resulting from retroviral reverse transcription in the presence of highly biased dNTP concentrations. Of the three reverse transcriptases (RTases) available, those of human immuno
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 1994, 91 (8), pp.3092-3096. ⟨10.1073/pnas.91.8.3092⟩
Proceedings of the National Academy of Sciences of the United States of America, 1994, 91 (8), pp.3092-3096. ⟨10.1073/pnas.91.8.3092⟩
The quasispecies model for RNA viruses predicts the existence of a replication error threshold beyond which there is a melting or total loss of sequence information. Retroviral G-->A hypermutation is probably an example. Here it is shown that G-->A t
Autor:
Liu, Y., Wang, C., Zhong, Y., Li, X., Dai, J., Ren, X., Xu, Z., Li, L., Yao, Z., Ji, D., Wang, L., Zhang, L., Wong, V. W. ‐S., Zoulim, F., Xu, D.
Publikováno v:
Journal of Viral Hepatitis
Journal of Viral Hepatitis, Wiley-Blackwell, 2011, 18 (4), pp.e29-39. ⟨10.1111/j.1365-2893.2010.01360.x⟩
Journal of Viral Hepatitis, Wiley-Blackwell, 2011, 18 (4), pp.e29-39. ⟨10.1111/j.1365-2893.2010.01360.x⟩
International audience; The study investigated the hepatitis B virus (HBV) genotypic resistance profile in 1803 nucleos(t)ide analogue (NA)-experienced Chinese patients with chronic HBV infection. Serum HBV DNA was extracted, and the reverse transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::07c3949b34fee4b22fc9f2d41c1c2ca5
https://hal.archives-ouvertes.fr/hal-00850143
https://hal.archives-ouvertes.fr/hal-00850143
Publikováno v:
Virology
Virology, Elsevier, 1991, 180 (2), pp.837-41
Virology, Elsevier, 1991, 180 (2), pp.837-41
The capsid protein and the reverse transcriptase of cauliflower mosaic virus (CaMV) are encoded by two genes (ORF IV and ORF V) that lie in different translation reading frames. A comparison can be drawn between the synthesis of both CaMV proteins an
Publikováno v:
Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 1990, 172 (2), pp.824-834. ⟨10.1128/jb.172.2.824-834.1990⟩
Journal of Bacteriology, 1990, 172 (2), pp.824-834. ⟨10.1128/jb.172.2.824-834.1990⟩
Journal of Bacteriology, American Society for Microbiology, 1990, 172 (2), pp.824-834. ⟨10.1128/jb.172.2.824-834.1990⟩
Journal of Bacteriology, 1990, 172 (2), pp.824-834. ⟨10.1128/jb.172.2.824-834.1990⟩
International audience; The rates of synthesis of a class of both secreted and intracellular degradative enzymes in Bacillus subtilis are controlled by a signal transduction pathway defined by at least four regulatory genes: degS, degU, degQ (formerl
Autor:
Dominique Rousset, Jean-Marc Reynes, Agnes P. Chetty, Richter Razafindratsimandresy, Justina Hollanda, Jean-Louis Soares
Publikováno v:
AIDS Research and Human Retroviruses
AIDS Research and Human Retroviruses, Mary Ann Liebert, 2007, 23 (6), pp.761-763. ⟨10.1089/aid.2007.0002⟩
AIDS Research and Human Retroviruses, Mary Ann Liebert, 2007, 23 (6), pp.761-763. ⟨10.1089/aid.2007.0002⟩
International audience; Subtype determination and drug resistance-associated mutations (DRM) detection were performed on 40 HIV-1 Western blot-positive sera detected, obtained from consecutive patients resident in the Seychelles and consulting the Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9422159e93f5cb155fd1c79ab293e12
https://hal-riip.archives-ouvertes.fr/pasteur-01835661/document
https://hal-riip.archives-ouvertes.fr/pasteur-01835661/document
Autor:
Jean-Luc Darlix, E.A. Derrington, Jonas Chnaiderman, Witold K. Surewicz, Pascal Leblanc, Dominique Dormont, Manuel Morillas, Daniel Marc, P.K. Nandi, Wieslaw Swietnicki, Caroline Gabus
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2001, 276 (22), pp.19301-19309. ⟨10.1074/jbc.M009754200⟩
Journal of Biological Chemistry, 2001, 276 (22), pp.19301-19309. ⟨10.1074/jbc.M009754200⟩
Journal of Biological Chemistry 22 (276), 19301-19309. (2001)
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2001, 276 (22), pp.19301-19309. ⟨10.1074/jbc.M009754200⟩
Journal of Biological Chemistry, 2001, 276 (22), pp.19301-19309. ⟨10.1074/jbc.M009754200⟩
Journal of Biological Chemistry 22 (276), 19301-19309. (2001)
International audience; Transmissible spongiform encephalopathies are fatal neurodegenerative diseases associated with the accumulation of a protease-resistant form of the prion protein (PrP). Although PrP is conserved in vertebrates, its function re
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 1996, 93 (2), pp.889-94. ⟨10.1073/pnas.93.2.889⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 1996, 93 (2), pp.889-94. ⟨10.1073/pnas.93.2.889⟩
Proceedings of the National Academy of Sciences of the United States of America, 1996, 93 (2), pp.889-94. ⟨10.1073/pnas.93.2.889⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 1996, 93 (2), pp.889-94. ⟨10.1073/pnas.93.2.889⟩
International audience; A rapid direct assay for polymerase-induced elongation along a given template is an obligate requirement for understanding the processivity of polymerization and the mode of action of drugs and inhibitors on this process. Surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cdb382b22d5123094ff6d56b5a0816
https://europepmc.org/articles/PMC40153/
https://europepmc.org/articles/PMC40153/