Small-RNA-mediated transgenerational silencing of histone genes impairs fertility in piRNA mutants

Autor: Blaise Li, Martino Ugolini, Damarys Loew, Germano Cecere, Aleksei Samolygo, Céline Didier, Eric Cornes, Meetali Singh, Giorgia Barucci, Piergiuseppe Quarato, Florent Dingli

Publikováno v: Nature cell biology
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2020, 22 (2), pp.235-245. ⟨10.1038/s41556-020-0462-7⟩
Nature Cell Biology, 2020, 22 (2), pp.235-245. ⟨10.1038/s41556-020-0462-7⟩

International audience; PIWI-interacting RNAs (piRNAs) promote fertility in many animals. However, whether this is due to their conserved role in repressing repetitive elements (REs) remains unclear. Here, we show that the progressive loss of fertili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983b418c96155c11b9d0637d29c2e4f8
https://doi.org/10.1038/s41556-020-0462-7

Antisense transcriptional interference mediates condition-specific gene repression in budding yeast

Autor: Antonia Doyen, Alicia Nevers, Christophe Malabat, Bertrand Néron, Gwenael Badis, Thomas Kergrohen, Alain Jacquier

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2018, 46 (12), pp.6009-6025. ⟨10.1093/nar/gky342⟩
Nucleic Acids Research, 2018, 46 (12), pp.6009-6025. ⟨10.1093/nar/gky342⟩

Pervasive transcription generates many unstable non-coding transcripts in budding yeast. The transcription of such noncoding RNAs, in particular antisense RNAs (asRNAs), has been shown in a few examples to repress the expression of the associated mRN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6025e7be12b7d285ac756d69d1201269
https://hal.archives-ouvertes.fr/hal-02349600

An in silico model for identification of small RNAs in whole bacterial genomes: characterization of antisense RNAs in pathogenic Escherichia coli and Streptococcus agalactiae strains

Autor: Marie Elise Caliot, Chantal Le Bouguénec, Christophe Pichon, Patrick Trieu-Cuot, Laurence du Merle

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2012, 40 (7), pp.2846-61. ⟨10.1093/nar/gkr1141⟩
Nucleic Acids Research, Oxford University Press, 2012, 40 (7), pp.2846-61. ⟨10.1093/nar/gkr1141⟩

International audience; Characterization of small non-coding ribonucleic acids (sRNA) among the large volume of data generated by high-throughput RNA-seq or tiling microarray analyses remains a challenge. Thus, there is still a need for accurate in s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0740a186665177d0e12932486bab88a6
https://doi.org/10.1093/nar/gkr1141

Characterization of the psbH precursor RNAs reveals a precise endoribonuclease cleavage site in the psbT/psbH intergenic region that is dependent on psbN gene expression

Autor: Damien Rondet, Livia Merendino, Thomas Pfannschmidt, Silva Lerbs-Mache, Mustafa Malik Ghulam, Fabien Chevalier

Publikováno v: Plant Molecular Biology Reporter
Plant Molecular Biology Reporter, Springer Verlag, 2015, 88 (4-5), pp.357-67. ⟨10.1007/s11103-015-0325-y⟩
Plant Molecular Biology Reporter, Springer Verlag, 2015, 88 (4-5), pp.357-67
Plant Molecular Biology Reporter, 2015, 88 (4-5), pp.357-67. ⟨10.1007/s11103-015-0325-y⟩

International audience; The plastid psbB operon harbours 5 genes, psbB, psbT, psbH, petB and petD. A sixth gene, the psbN gene, is located on the opposite DNA strand in the psbT/psbH intergenic region. Its transcription produces antisense RNA to a la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46704a351495bb6fdab72df76210ea3f
https://hal.archives-ouvertes.fr/hal-01166959

Small RNA genes expressed from Staphylococcus aureus genomic and pathogenicity islands with specific expression among pathogenic strains

Autor: Christophe Pichon, Brice Felden

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2005, 102 (40), pp.14249-54. ⟨10.1073/pnas.0503838102⟩
Proceedings of the National Academy of Sciences of the United States of America, 2005, 102 (40), pp.14249-54. ⟨10.1073/pnas.0503838102⟩

Small RNA (sRNA) genes are expressed in all organisms, primarily as regulators of translation and message stability. We have developed comparative genomic approaches to identify sRNAs that are expressed by Staphylococcus aureus , the most common caus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0c18396f6c17f12c1ad80dfbe2d955
https://doi.org/10.1073/pnas.0503838102