Zobrazeno 1 - 3
of 3
pro vyhledávání: '"MESH: Pyrimidine Dimers"'
Autor:
Keronninn M. Lima-Bessa, Carlos Frederico Martins Menck, Alain Sarasin, Vanessa Chiganças, Anne Stary
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2008, 68 (15), pp.6074-6083. ⟨10.1158/0008-5472.CAN-07-6695⟩
Cancer Research, American Association for Cancer Research, 2008, 68 (15), pp.6074-6083. ⟨10.1158/0008-5472.CAN-07-6695⟩
Most trichothiodystrophy (TTD) patients present mutations in the xeroderma pigmentosum D (XPD) gene, coding for a subunit of the transcription/repair factor IIH (TFIIH) complex involved in nucleotide excision repair (NER) and transcription. After UV
Autor:
Alain Sarasin, Melissa Gava Armelini, Gustavo P. Amarante-Mendes, Carlos Frederico Martins Menck, Vanessa Chiganças, Jacqueline F. Jacysyn, Keronninn M. Lima-Bessa
Publikováno v:
DNA Repair
DNA Repair, Elsevier, 2008, 7 (2), pp.303-12. ⟨10.1016/j.dnarep.2007.11.003⟩
DNA Repair, Elsevier, 2008, 7 (2), pp.303-12. ⟨10.1016/j.dnarep.2007.11.003⟩
Ultraviolet (UV) light generates two major DNA lesions: cyclobutane pyrimidine dimers (CPDs) and pyrimidine-(6-4)-pyrimidone photoproducts (6-4PPs), but the specific participation of these two lesions in the deleterious effects of UV is a longstandin
Publikováno v:
Biophysical Journal
Biophysical Journal, Biophysical Society, 2005, 88 (4), pp.2766-78. ⟨10.1529/biophysj.104.049015⟩
Biophysical Journal, Biophysical Society, 2005, 88 (4), pp.2766-78. ⟨10.1529/biophysj.104.049015⟩
International audience; Oxidative guanine lesions were analyzed, at the nucleotide level, within DNA exposed to nanosecond ultraviolet (266 nm) laser pulses of variable intensity (0.002-0.1 J/cm(2)). Experiments were carried out, at room temperature,