Zika Virus Targets Multiple Tissues and Cell Types During the First Trimester of Pregnancy

Autor: Francisco Veas, Nabila Jabrane-Ferrat

Publikováno v: Zika Virus
Zika Virus, 2142, Springer US, pp.235-249, 2020, Methods in Molecular Biology, ⟨10.1007/978-1-0716-0581-3_18⟩
Zika Virus : Methods and protocols
Kobinger G.; Racine T. Zika Virus : Methods and protocols, 2142, Humana, pp.235-249, 2020, Methods in Molecular Biology, 978-1-0716-0580-6. ⟨10.1007/978-1-0716-0581-3_18⟩
Methods in Molecular Biology ISBN: 9781071605806

International audience; The 2016 Zika virus (ZIKV) outbreak in the Americas has been characterized by an increased association frequency of fetal neuropathological abnormalities. To have a comprehensive and accurate knowledge of key elements of the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834256b3a184288f7d10bbe85b24bc05
https://hal-cnrs.archives-ouvertes.fr/hal-03411920

A genetic variant controls interferon-β gene expression in human myeloid cells by preventing C/EBP-β binding on a conserved enhancer

Autor: Didier Busso, Lluis Quintana-Murci, Paul-Henri Romeo, Juliette Hamroune, Anaïs Assouvie, Germain Rousselet, Maxime Rotival

Publikováno v: PLoS Genetics
PLoS Genetics, Public Library of Science, 2020, 16 (11), pp.e1009090. ⟨10.1371/journal.pgen.1009090⟩
PLoS Genetics, Vol 16, Iss 11, p e1009090 (2020)
PLoS Genetics, 2020, 16 (11), pp.e1009090. ⟨10.1371/journal.pgen.1009090⟩

Interferon β (IFN-β) is a cytokine that induces a global antiviral proteome, and regulates the adaptive immune response to infections and tumors. Its effects strongly depend on its level and timing of expression. Therefore, the transcription of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a80ae8119a6c1f941629a571c21e1be
https://pubmed.ncbi.nlm.nih.gov/33147208

Increased expression of ATP12A proton pump in cystic fibrosis airways

Autor: Davide Tosi, Arianna Venturini, Luis J. V. Galietta, Alessandro Palleschi, Paolo Scudieri, Isabelle Sermet-Gaudelus, Gilles Crambert, Ilaria Musante, Pablo Martín-Vasallo, P. Morelli, Emanuela Caci, Gabrielle Planelles, Christine Walter

Publikováno v: JCI Insight
JCI Insight, American Society for Clinical Investigation, 2018, 3 (20), ⟨10.1172/jci.insight.123616⟩

International audience; Proton secretion mediated by ATP12A protein on the surface of the airway epithelium may contribute to cystic fibrosis (CF) lung disease by favoring bacterial infection and airway obstruction. We studied ATP12A in fresh bronchi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c864055b487b8969f87e6a1233a66e3b
https://hal.archives-ouvertes.fr/hal-02466266

Lipase inhibitor orlistat prevents hepatitis B virus infection by targeting an early step in the virus life cycle

Autor: Ulrike Protzer, Alma Zernecke, Jochen M. Wettengel, Almut Glinzer, Katrin Singethan, Knud Esser, Julie Lucifora

Publikováno v: Antiviral Research
Antiviral Research, Elsevier Masson, 2018, 151, pp.4-7. ⟨10.1016/j.antiviral.2018.01.001⟩
Antiviral Res. 151, 4-7 (2018)

International audience; Hepatitis B Virus (HBV) is a strictly hepatotropic pathogen which is very efficiently targeted to the liver and into its host cell, the hepatocyte. The sodium taurocholate co-transporting polypeptide (NTCP) has been identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ae229a201842a982bbf8673433c2eb
https://hal.archives-ouvertes.fr/hal-03315719

In Situ Fixation Redefines Quiescence and Early Activation of Skeletal Muscle Stem Cells

Autor: Léo Machado, Joana Esteves de Lima, Odile Fabre, Caroline Proux, Rachel Legendre, Anikó Szegedi, Hugo Varet, Lars Roed Ingerslev, Romain Barrès, Frédéric Relaix, Philippos Mourikis

Publikováno v: Cell Reports
Cell Reports, 2017, 21 (7), pp.1982-1993. ⟨10.1016/j.celrep.2017.10.080⟩
Cell Reports, Elsevier Inc, 2017, 21 (7), pp.1982-1993. ⟨10.1016/j.celrep.2017.10.080⟩
Machado, L, Esteves de Lima, J, Fabre, O, Proux, C, Legendre, R, Szegedi, A, Varet, H, Ingerslev, L R, Barrès, R, Relaix, F & Mourikis, P 2017, ' In Situ Fixation Redefines Quiescence and Early Activation of Skeletal Muscle Stem Cells ', Cell Reports, vol. 21, no. 7, pp. 1982-1993 . https://doi.org/10.1016/j.celrep.2017.10.080
Cell Reports, Vol 21, Iss 7, Pp 1982-1993 (2017)

Summary: State of the art techniques have been developed to isolate and analyze cells from various tissues, aiming to capture their in vivo state. However, the majority of cell isolation protocols involve lengthy mechanical and enzymatic dissociation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a5411b86564d3baa766cd564404ba9a8
https://hal-pasteur.archives-ouvertes.fr/pasteur-02562451