Zobrazeno 1 - 4
of 4
pro vyhledávání: '"MESH: Positive Transcriptional Elongation Factor B"'
Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma
Autor:
Alvaro C. Laga, John M. Asara, Howard Y. Chang, Justin L. Tan, Brian T. Do, Leonard I. Zon, Anne Bothmer, Richard M. White, David H. Price, Ng Shyh-Chang, Ryan A. Flynn, Nicole Pandell, Song Yang, Violaine Saint-André, Yoon Jung Kim, Zi Peng Fan, Koh Fujinaga, Elliott J. Hagedorn, Serine Avagyan, Tae Hoon Kim, Cristina Santoriello, B. Matija Peterlin, Ellen van Rooijen, John G. Clohessy, John E. Brogie, Richard A. Young, Celeste B. Greer, Yi Zhou, Pier Paolo Pandolfi, Rachel D. Fogley, Julien Ablain
Publikováno v:
Molecular Cell
Molecular Cell, 2016, 62 (1), pp.34-46. ⟨10.1016/j.molcel.2016.03.013⟩
Molecular Cell, Elsevier, 2016, 62 (1), pp.34-46. ⟨10.1016/j.molcel.2016.03.013⟩
PMC
Molecular cell, vol 62, iss 1
Molecular Cell, 2016, 62 (1), pp.34-46. ⟨10.1016/j.molcel.2016.03.013⟩
Molecular Cell, Elsevier, 2016, 62 (1), pp.34-46. ⟨10.1016/j.molcel.2016.03.013⟩
PMC
Molecular cell, vol 62, iss 1
International audience; Studying cancer metabolism gives insight into tumorigenic survival mechanisms and susceptibilities. In melanoma, we identify HEXIM1, a transcription elongation regulator, as a melanoma tumor suppressor that responds to nucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2be414500e23e7e55cf569d834dacf
https://hal-pasteur.archives-ouvertes.fr/pasteur-02871949
https://hal-pasteur.archives-ouvertes.fr/pasteur-02871949
Autor:
Ajit Kumar, Fatah Kashanchi, Meisheng Zhou, Longwen Deng, Anne Pumfery, Hyeon Ung Park, Vincent Lacoste, John N. Brady
Publikováno v:
Journal of Virology
Journal of Virology, American Society for Microbiology, 2004, 78 (24), pp.13522-13533. ⟨10.1128/JVI.78.24.13522-13533.2004⟩
Journal of Virology, American Society for Microbiology, 2004, 78 (24), pp.13522-13533. ⟨10.1128/JVI.78.24.13522-13533.2004⟩
The human immunodeficiency virus type 1 (HIV-1) Tat protein recruits positive transcription elongation factor b (P-TEFb) to the transactivation response (TAR) RNA structure to facilitate formation of processive transcription elongation complexes (TEC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c3252b2ce863e749e4d2792390dd08
https://doi.org/10.1128/jvi.78.24.13522-13533.2004
https://doi.org/10.1128/jvi.78.24.13522-13533.2004
Autor:
Elodie Van Herreweghe, Bernard Monsarrat, Isabelle Goiffon, Sylvain Egloff, Tamás Kiss, Beáta E. Jády, Carine Froment
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2007, 26 (15), pp.3570-80. ⟨10.1038/sj.emboj.7601783⟩
EMBO Journal, EMBO Press, 2007, 26 (15), pp.3570-80. ⟨10.1038/sj.emboj.7601783⟩
The 7SK small nuclear RNA (snRNA) regulates RNA polymerase II transcription elongation by controlling the protein kinase activity of the positive transcription elongation factor b (P-TEFb). In cooperation with HEXIM1, the 7SK snRNA sequesters P-TEFb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1478fd21300fad531486e676470e25fc
https://pubmed.ncbi.nlm.nih.gov/17611602
https://pubmed.ncbi.nlm.nih.gov/17611602
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2006, 26, pp.630-642
Molecular and Cellular Biology, American Society for Microbiology, 2006, 26 (2), pp.630-42. ⟨10.1128/MCB.26.2.630-642.2006⟩
Molecular and Cellular Biology, American Society for Microbiology, 2006, 26, pp.630-642
Molecular and Cellular Biology, American Society for Microbiology, 2006, 26 (2), pp.630-42. ⟨10.1128/MCB.26.2.630-642.2006⟩
The positive transcription elongation factor b (P-TEFb), a complex of Cdk9 and cyclin T1/T2, stimulates transcription by phosphorylating RNA polymerase II. The 7SK small nuclear RNA, in cooperation with HEXIM1 protein, functions as a general polymera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae74189e781a057eb13f6f87dc54b239
https://hal.archives-ouvertes.fr/hal-00021148
https://hal.archives-ouvertes.fr/hal-00021148