Zobrazeno 1 - 10
of 338
pro vyhledávání: '"MESH: Polymorphism, Genetic"'
Autor:
Leonie S. Lautz, Franca M. Buratti, Emma Di Consiglio, Jean-Lou Dorne, Laura Turco, Camille Béchaux, Susanna Vichi, Emanuela Testai, K. Darney
Publikováno v:
Toxicology Letters
Toxicology Letters, Elsevier, 2020, 337, pp.78-90. ⟨10.1016/j.toxlet.2020.11.007⟩
Toxicology Letters, Elsevier, 2020, 337, pp.78-90. ⟨10.1016/j.toxlet.2020.11.007⟩
International audience; The input into the QIVIVE and Physiologically-Based kinetic and dynamic models of drug metabolising enzymes performance and their inter-individual differences significantly improve the modelling performance, supporting the dev
Autor:
Patrick Schmid, Enos Bernasconi, Ioannis Theodorou, Sophia S. Wang, Pejman Mohammadi, Paul J. McLaren, Huldrych F. Günthard, Matthias Cavassini, Charles S. Rabkin, Matthias Hoffmann, Christian Hammer, Shehnaz K. Hussain, Jacques Fellay, Andri Rauch, Cécile Goujard, Laurence Meyer, Jonathan Niay, Caroline Besson, Nava Ehsan, Tiphaine Oudot-Mellakh, Dominique Costagliola, Manuel Battegay, Christian W. Thorball, Federico Santoni
Publikováno v:
Haematologica
Haematologica, Ferrata Storti Foundation, 2021, 106 (8), pp.2233-2241. ⟨10.3324/haematol.2020.247023⟩
Haematologica, vol. 106, no. 8, pp. 2233-2241
Haematologica, Ferrata Storti Foundation, 2021, 106 (8), pp.2233-2241. ⟨10.3324/haematol.2020.247023⟩
Haematologica, vol. 106, no. 8, pp. 2233-2241
International audience; Human immunodeficiency virus (HIV) infection is associated with an increased risk of non-Hodgkin lymphoma (NHL). Even in the era of suppressive antiretroviral treatment, HIV-infected individuals remain at higher risk of develo
Autor:
Kenneth Chappell, Romain Colle, Jérôme Bouligand, Séverine Trabado, Bruno Fève, Laurent Becquemont, Emmanuelle Corruble, Céline Verstuyft
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2023, 24 (1), pp.497. ⟨10.3390/ijms24010497⟩
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 497
International Journal of Molecular Sciences, 2023, 24 (1), pp.497. ⟨10.3390/ijms24010497⟩
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 497
Major depressive disorder (MDD) is the leading cause of disability worldwide. Treatment with antidepressant drugs (ATD), which target monoamine neurotransmitters including serotonin (5HT), are only modestly effective. Monoamine oxidase (MAO) metaboli
Autor:
Laura Turco, Leonie S. Lautz, K. Darney, Jean-Lou Dorne, Emanuela Testai, Franca M. Buratti, Susanna Vichi, Emma Di Consiglio
Publikováno v:
Toxicology Letters
Toxicology Letters, Elsevier, 2021, ⟨10.1016/j.toxlet.2021.07.019⟩
Toxicology Letters, Elsevier, 2021, ⟨10.1016/j.toxlet.2021.07.019⟩
International audience; The open source database "OpenCYP database" has been developed based on the results of extensive literature searches from the peer-reviewed literature. OpenCYP provides data on human variability on baseline of activities and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d2aa3a48e299b0e02118b207d50ddd
https://hal-anses.archives-ouvertes.fr/anses-03319826/file/Vichi_2021.pdf
https://hal-anses.archives-ouvertes.fr/anses-03319826/file/Vichi_2021.pdf
Autor:
Astrid T. Groot, Brad S. Coates, David G. Heckel, Melanie Unbehend, Teun Dekker, Fotini Koutroumpa, Erik B. Dopman, Genevieve M. Kozak
Publikováno v:
Nature Communications
Nature Communications, 2021, 12 (1), pp.2818. ⟨10.1038/s41467-021-23026-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2818. ⟨10.1038/s41467-021-23026-x⟩
Nature Communications, 12:2818. Nature Publishing Group
Nature Communications, 2021, 12 (1), pp.2818. ⟨10.1038/s41467-021-23026-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2818. ⟨10.1038/s41467-021-23026-x⟩
Nature Communications, 12:2818. Nature Publishing Group
The sex pheromone system of ~160,000 moth species acts as a powerful form of assortative mating whereby females attract conspecific males with a species-specific blend of volatile compounds. Understanding how female pheromone production and male pref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f57cf501264c41a6dbad628ac10751
https://hal.sorbonne-universite.fr/hal-03250080
https://hal.sorbonne-universite.fr/hal-03250080
Autor:
Natan Gadoth, Birgit Högl, Rosa Hasan, G. Plazzi, Andrea N. Goldstein-Piekarski, Makrina Daniilidou, Thomas J Rico, Smaranda Leu-Semenescu, Ryan P. Hillary, Neal M. Farber, Guy D. Leschziner, Emmanuel Mignot, Yakov Sivan, Michel Lecendreux, José L. Vicario, Hanna Ollila, Juliette Faraco, Sona Nevsimalova, Isabelle Arnulf, Fang Han, Francesca Canellas, Pauline Dodet, Patrice Bourgin, Geert Mayer, Fabio Pizza, Makoto Honda, Yu-Shu Huang, Kazuhiko Kume, Rosa Peraita-Adrados, Ling Lin, David B. Rye, Takashi Kanbayashi, Eileen B. Leary, Seung Chul Hong, Emmanuel H. During, Anne-Marie Landtblom, Yves Dauvilliers, Aditya Ambati
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (12), pp.e2005753118. ⟨10.1073/pnas.2005753118⟩
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (12), pp.e2005753118. ⟨10.1073/pnas.2005753118⟩
Kleine-Levin syndrome (KLS) is a rare disorder characterized by severe episodic hypersomnia, with cognitive impairment accompanied by apathy or disinhibition. Pathophysiology is unknown, although imaging studies indicate decreased activity in hypotha
Autor:
Himanshu Gupta, Beatriz Galatas, Didier Menard, Wilson Simone, Silvie Huijben, Lidia Nhamussua, Quique Bassat, Pedro Aide, Francisco Saute, Pau Cisteró, Pascal Ringwald, Arlindo Chidimatembue, Alfredo Mayor, Pedro L. Alonso, Gloria Matambisso, N. Regina Rabinovich
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
PLoS ONE, 2020, 15 (10), pp.e0240174. ⟨10.1371/journal.pone.0240174⟩
PLoS ONE, Vol 15, Iss 10, p e0240174 (2020)
PLoS ONE, Public Library of Science, 2020, 15 (10), pp.e0240174. ⟨10.1371/journal.pone.0240174⟩
Universidad de Barcelona
PLoS ONE
PLoS ONE, 2020, 15 (10), pp.e0240174. ⟨10.1371/journal.pone.0240174⟩
PLoS ONE, Vol 15, Iss 10, p e0240174 (2020)
PLoS ONE, Public Library of Science, 2020, 15 (10), pp.e0240174. ⟨10.1371/journal.pone.0240174⟩
Background Mass drug administration (MDA) can rapidly reduce the burden of Plasmodium falciparum (Pf). However, concerns remain about its contribution to select for antimalarial drug resistance. Methods We used Sanger sequencing and real-time PCR to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a4494414bbe3e473738288fe364ffe
Publikováno v:
Toxicology Letters
Toxicology Letters, Elsevier, 2021, 337, pp.111-120. ⟨10.1016/j.toxlet.2020.11.016⟩
Toxicology Letters, 2021, 337, pp.111-120. ⟨10.1016/j.toxlet.2020.11.016⟩
Toxicology Letters, Elsevier, 2021, 337, pp.111-120. ⟨10.1016/j.toxlet.2020.11.016⟩
Toxicology Letters, 2021, 337, pp.111-120. ⟨10.1016/j.toxlet.2020.11.016⟩
International audience; Quantifying variability in pharmacokinetics (PK) and toxicokinetics (TK) provides a science-based approach to refine uncertainty factors (UFs) for chemical risk assessment. In this context, genetic polymorphisms in cytochromes
Autor:
Bonneau, Manon, Atyame Nten, Célestine, Beji, Marwa, Justy, Fabienne, Cohen-Gonsaud, Martin, Sicard, Mathieu, Weill, Mylène
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature Communications, 2018, 9 (1), pp.319. ⟨10.1038/s41467-017-02749-w⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.319. ⟨10.1038/s41467-017-02749-w⟩
Nature Communications
Nature Communications, 2018, 9 (1), pp.319. ⟨10.1038/s41467-017-02749-w⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.319. ⟨10.1038/s41467-017-02749-w⟩
International audience; Culex pipiens mosquitoes are infected with Wolbachia (wPip) that cause an important diversity of cytoplasmic incompatibilities (CIs). Functional transgenic studies have implicated the cidA-cidB operon from wPip and its homolog
Autor:
Shaymaa Khazaal, Zhijian Cao, Yingliang Wu, Jean-Marc Sabatier, George El-Arif, Antonella Farhat, Ziad Fajloun, Hervé Kovacic, Ziad Abi Khattar, Cédric Annweiler
Publikováno v:
Molecules, Vol 26, Iss 6945, p 6945 (2021)
Molecules
Molecules, 2021, 26 (22), pp.6945. ⟨10.3390/molecules26226945⟩
Molecules
Molecules, 2021, 26 (22), pp.6945. ⟨10.3390/molecules26226945⟩
International audience; The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), was first identified in Eastern Asia (Wuhan, China) in December 2019. The virus then spread to