Human single-chain urokinase is activated by the omptins PgtE of Salmonella enterica and Pla of Yersinia pestis despite mutations of active site residues

Autor: Hanna M, Järvinen, Liisa, Laakkonen, Johanna, Haiko, Tiira, Johansson, Katri, Juuti, Marjo, Suomalainen, Carmen, Buchrieser, Nisse, Kalkkinen, Timo K, Korhonen

Publikováno v: Molecular Microbiology
Molecular Microbiology, Wiley, 2013, 89 (3), pp.507-517. ⟨10.1111/mmi.12293⟩
Molecular Microbiology, 2013, 89 (3), pp.507-517. ⟨10.1111/mmi.12293⟩

International audience; Fibrinolysis is important in cell migration and tightly regulated by specific inhibitors and activators; of the latter, urokinase (uPA) associates with enhancement of cell migration. Active uPA is formed through cleavage of th

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https://hal-pasteur.archives-ouvertes.fr/pasteur-01336155