Výsledky vyhledávání - "MESH: Phrenic Nerve / drug effects"

Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library

Autor: Thomas Schirrmann, Yvonne Liu, Sebastian Miethe, André Frenzel, Christine Rasetti-Escargueil, Philippe Thullier, Arnaud Avril, Dorothea Sesardic, Michael Hust, Thibaut Pelat, Siham Chahboun

Publikováno v: mAbs
mAbs, Taylor & Francis, 2014, 6 (2), pp.446-459. ⟨10.4161/mabs.27773⟩

International audience; Botulinum toxins (BoNTs) are among the most toxic substances on earth, with serotype A toxin being the most toxic substance known. They are responsible for human botulism, a disease characterized by flaccid muscle paralysis th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b79c4b03277782d941f11d6ab9496dc
https://pubmed.ncbi.nlm.nih.gov/24492304

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Phrenic nerve-hemidiaphragm as a highly sensitive replacement assay for determination of functional botulinum toxin antibodies

Autor: Peter Rigsby, Yvonne Liu, Dorothea Sesardic, Christine Rasetti-Escargueil, R.G.A. Jones

Publikováno v: Toxicon
Toxicon, Elsevier, 2011, 57 (7-8), pp.1008-1016. ⟨10.1016/j.toxicon.2011.04.003⟩

International audience; Botulinum neurotoxins induce a prolonged muscle paralysis by specifically blocking the release of neuronal transmitters from peripheral nerve junctions. Potency testing of toxin and antitoxin therapies is entirely dependent on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7107413fc8d6b31213cd3601c1f9052d
https://hal-pasteur.archives-ouvertes.fr/pasteur-02873012

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Measurement of botulinum types A, B and E neurotoxicity using the phrenic nerve-hemidiaphragm: improved precision with in-bred mice

Autor: R.G.A. Jones, Yvonne Liu, Christine Rasetti-Escargueil, Dorothea Sesardic

Publikováno v: Toxicon
Toxicon, Elsevier, 2009, 53 (5), pp.503-511. ⟨10.1016/j.toxicon.2009.01.019⟩

International audience; Botulinum neurotoxins induce a prolonged muscle paralysis by specifically blocking the release of neuronal transmitters from peripheral nerve junctions. The current method for assessing the potency of botulinum toxin and antit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d634d63ba1c0a31bd33c471cc35bf212
https://pubmed.ncbi.nlm.nih.gov/19673096

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