Characterization of neutralizing antibodies reacting with the 213-224 amino-acid segment of human galectin-9

Autor: Lhuillier, Claire, Barjon, Clément, Baloche, Valentin, Niki, Toshiro, Gelin, Aurore, Mustapha, Rami, Claër, Laetitia, Hoos, Sylviane, Chiba, Yoichi, Ueno, Masaki, Hirashima, Mitsuomi, Wei, Ming, Moralès, Olivier, Raynal, Bertrand, Delhem, Nadira, Dellis, Olivier, Busson, Pierre

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2018, 13 (9), pp.e0202512. ⟨10.1371/journal.pone.0202512⟩
PLoS ONE, 2018, 13 (9), pp.e0202512. ⟨10.1371/journal.pone.0202512⟩

International audience; Extra-cellular galectin-9 (gal-9) is an immuno-modulatory protein with predominant immuno-suppressive effects. Inappropriate production of gal-9 has been reported in several human malignancies and viral diseases like nasophary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::36aec931ee5240029bd568e3833ad99b
https://hal.archives-ouvertes.fr/hal-02414847

Functional reconstitution of cell-free synthesized purified K v channels

Autor: Xavier Henry, Sandra Cortes, Michel De Waard, Beate Bersch, Béatrice Schaack, Stéphane Renauld

Publikováno v: Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2017, 1859 (12), pp.2373-2380. ⟨10.1016/j.bbamem.2017.09.002⟩
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2017, 1859 (12), pp.2373-2380. 〈10.1016/j.bbamem.2017.09.002〉
Biochimica et Biophysica Acta:Biomembranes, 2017, 1859 (12), pp.2373-2380. ⟨10.1016/j.bbamem.2017.09.002⟩

International audience; The study of ion channel activity and the screening of possible inhibitor molecules require reliable methods for production of active channel proteins, their insertion into artificial membranes and for the measurement of their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7298e9bf404c703977b07c40d6eb4f
https://hal.archives-ouvertes.fr/hal-01593501

Phosphatidylserine-expressing cell by-products in transfusion: A pro-inflammatory or an anti-inflammatory effect?

Autor: L. Bardiaux, Francine Garnache-Ottou, Sylvain Perruche, Philipppe Saas, Fanny Angelot, Estelle Seilles

Publikováno v: Transfusion Clinique et Biologique
Transfusion Clinique et Biologique, Elsevier, 2012, 19 (3), pp.90-7. ⟨10.1016/j.tracli.2012.02.002⟩

International audience; Labile blood products contain phosphatidylserine-expressing cell dusts, including apoptotic cells and microparticles. These cell by-products are produced during blood product process or storage and derived from the cells of in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc515357235e498e15f662188cc4aa2b
https://doi.org/10.1016/j.tracli.2012.02.002

The catalytic domains of C lostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid

Autor: Carolina, Varela Chavez, Sylviane, Hoos, Georges Michel, Haustant, Alexandre, Chenal, Patrick, England, Arnaud, Blondel, Serge, Pauillac, D Borden, Lacy, Michel Robert, Popoff

Publikováno v: Cellular Microbiology
Cellular Microbiology, 2015, 17 (10), pp.1477-1493. ⟨10.1111/cmi.12449⟩
Cellular Microbiology, Wiley, 2015, 17 (10), pp.1477-1493. ⟨10.1111/cmi.12449⟩

International audience; Clostridium sordellii lethal toxin (TcsL) is a potent virulence factor belonging to the large clostridial glucosylating toxin family. TcsL enters target cells via receptor-mediated endocytosis and delivers the N-terminal catal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::29c1ef3705bb855f04d7eca191a56ea5
https://hal-pasteur.archives-ouvertes.fr/pasteur-01400914

Investigations on the C1q–Calreticulin–Phosphatidylserine Interactions Yield New Insights into Apoptotic Cell Recognition

Autor: Philippe Frachet, Gérard J. Arlaud, Mélanie Verneret, Christine Gaboriaud, Pascale Tacnet-Delorme, Helena Paidassi, Wai Li Ling, Karen Duus, Gunnar Houen

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2011, 408 (2), pp.277-290. ⟨10.1016/j.jmb.2011.02.029⟩
Journal of Molecular Biology, 2011, 408 (2), pp.277-290. ⟨10.1016/j.jmb.2011.02.029⟩

International audience; Both C1q and calreticulin (CRT) are involved in the recognition of apoptotic cells. CRT was initially characterized as a receptor for the C1q collagen-like fragment (CLF), whereas C1q was shown to bind apoptotic cells through

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c6855f5f38edbf2f1a9e139d17154f
https://hal.archives-ouvertes.fr/hal-01991883