Phenanthrolinic analogs of quinolones show antibacterial activity against M. tuberculosis

Autor: Patrick Dallemagne, Mahama Ouattara, Cédric Lecoutey, Songuigama Coulibaly, Julien Briffotaux, Maria Virginia Buchieri, Christophe Rochais, Noelia Alonso-Rodriguez, Mena Cimino, Brigitte Gicquel, Damien Mornico

Publikováno v: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 207, pp.112821. ⟨10.1016/j.ejmech.2020.112821⟩
European Journal of Medicinal Chemistry, 2020, 207, pp.112821. ⟨10.1016/j.ejmech.2020.112821⟩

International audience; Several phenanthrolinic analogs of quinolones have been synthesized and their antibacterial activity tested against Mycobacterium tuberculosis, other mycobacterial species and bacteria from other genera. Some of them show high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264c1673e515d98e3659bafffbd189cb
https://hal-pasteur.archives-ouvertes.fr/pasteur-03261309

An integrated methodology for data processing in dynamic force spectroscopy of ligand–receptor binding

Autor: Odorico, M., Teulon, J.-M., Berthoumieu, O., Chen, S-w, Parot, P., Pellequer, Jean-Luc, Chen, S.-w.W.

Publikováno v: Ultramicroscopy
Ultramicroscopy, Elsevier, 2007, 107 (10-11), pp.887-894. ⟨10.1016/j.ultramic.2007.04.019⟩
Ultramicroscopy, 2007, 107 (10-11), pp.887-894. ⟨10.1016/j.ultramic.2007.04.019⟩

International audience; Dynamic force spectroscopy (DFS), using atomic force microscopy (AFM), is a powerful tool to study ligand-receptor binding. The interaction mode of two binding partners is investigated by exploring stochastic behaviors of bond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9365d1a025862498fe9e8ace69eb837
https://doi.org/10.1016/j.ultramic.2007.04.019

Triplex-forming oligonucleotide-orthophenanthroline conjugates for efficient targeted genome modification

Autor: Fabio Cannata, Carine Giovannangeli, Erika Brunet, Slimane Ait-Si-Ali, Ulysse Asseline, Loïc Perrouault, Jean-Paul Concordet, Victoria Roig

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2008, 105 (28), pp.9576-81. ⟨10.1073/pnas.0710433105⟩

International audience; The inefficiency of gene modification by homologous recombination can be overcome by the introduction of a double-strand break (DSB) in the target. Engineering the endonucleases needed, however, remains a challenging task that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba853f2767bbdd1b4ba237e58f21bf9
https://hal.archives-ouvertes.fr/hal-00408029

Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis

Autor: Stephane Gesta, Astrid Rey, Marie-Françoise Simon, David Sibrac, Max Lafontan, Philippe Valet, Jean Sébastien Saulnier-Blache, Alexia Girard

Publikováno v: Europe PubMed Central
Scopus-Elsevier
Journal of Lipid Research, Vol 43, Iss 6, Pp 904-910 (2002)
J Lipid Res
J Lipid Res, 2002, 43 (6), pp.904-10

The aim of the present work was to depict the metabolic pathways involved in extracellular production of lysophosphatidic acid (LPA) by adipocytes. LPA was followed by quantifying the accumulation of LPA in the incubation medium (conditioned medium,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4f7d1e1a57ad0d373ebb67a016b3d6
http://europepmc.org/abstract/med/12032165