Primaquine for Plasmodium vivax radical cure: What we do not know and why it matters

Autor: Kieran Tebben, Benoit Witkowski, David Serre, Jean Popovici

Publikováno v: International Journal for Parasitology: Drugs and Drug Resistance, Vol 15, Iss, Pp 36-42 (2021)
International journal for parasitology. Drugs and drug resistance
International journal for parasitology. Drugs and drug resistance, Elsevier, 2021, 15, pp.36-42. ⟨10.1016/j.ijpddr.2020.12.004⟩
International Journal for Parasitology: Drugs and Drug Resistance

Plasmodium vivax radical cure requires the administration of a blood schizonticide for killing blood-stage parasites and the addition of a drug able to kill hypnozoites, the dormant parasite stages residing in the liver of infected patients. All drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f412ed4175944bc01287eaafb8fdde2d
http://www.sciencedirect.com/science/article/pii/S221132072030052X

Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion

Autor: Rachidi, Najma, Knippschild, Uwe, Späth, Gerald F

Publikováno v: Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.655700. ⟨10.3389/fcimb.2021.655700⟩
Frontiers in Cellular and Infection Microbiology, Frontiers, 2021, 11, pp.655700. ⟨10.3389/fcimb.2021.655700⟩

International audience; Casein Kinase 1 (CK1) family members are serine/threonine protein kinases that are involved in many biological processes and highly conserved in eukaryotes from protozoan to humans. Even though pathogens exploit host CK1 signa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5935630a9b96f615ed01c293dad64088
http://europepmc.org/articles/PMC8044801

Evaluation of a Flotation Adapted Parasep® for Stool Ova and Parasite Examination

Autor: Nicolas Monnin, Anne Debourgogne, Brieuc Lefaure, Marie Machouart, Clément Kebbabi

Publikováno v: The Journal of Parasitology
The Journal of Parasitology, 1970, 105 (3), pp.480-483. ⟨10.1645/18-115⟩

International audience; Stool ova and parasite examination using concentration methods remains the gold standard for the investigation of digestive parasitosis. Recently, single-use filtration devices have been marketed for stool concentration sedime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c74e45ac6c6e0f10d1e7978481d6a6d
https://pubmed.ncbi.nlm.nih.gov/31251704

Pathogen manipulation of B cells: the best defence is a good offence

Autor: Armelle Phalipon, Katharina Nothelfer, Philippe J. Sansonetti

Publikováno v: Nature Reviews Microbiology
Nature Reviews Microbiology, 2015, 13 (3), pp.173-184. ⟨10.1038/nrmicro3415⟩
Nature Reviews Microbiology, Nature Publishing Group, 2015, 13 (3), pp.173-184. ⟨10.1038/nrmicro3415⟩
Nature Reviews Microbiology, 13(3), 173-184. Nature Publishing Group

International audience; B cells have long been regarded as simple antibody production units, but are now becoming known as key players in both adaptive and innate immune responses. However, several bacteria, viruses and parasites have evolved the abi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5568652c85a94f5593b9fdb18eca0f23
https://doi.org/10.1038/nrmicro3415

The nuclear envelope and gene organization in parasitic protozoa: Specializations associated with disease

Autor: Lucy Glover, Kirk W. Deitsch, Samson O. Obado

Publikováno v: Molecular and Biochemical Parasitology
Molecular and Biochemical Parasitology, 2016, 209 (1-2), pp.104-113. ⟨10.1016/j.molbiopara.2016.07.008⟩
Molecular and Biochemical Parasitology, Elsevier, 2016, 209 (1-2), pp.104-113. ⟨10.1016/j.molbiopara.2016.07.008⟩

International audience; The parasitic protozoa Trypanosoma brucei and Plasmodium falciparum are lethal human parasites that have developed elegant strategies of immune evasion by antigenic variation. Despite the vast evolutionary distance between the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6257f9d65c237ad430da1b1583e4bb51
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107121