Zobrazeno 1 - 10
of 37
pro vyhledávání: '"MESH: Osteosarcoma"'
Autor:
Roberta Mazzone, Piero Picci, Katia Scotlandi, Michela Pasello, Patrizia Nanni, Giordano Nicoletti, Maria Cristina Manara, Antonello Mai, Clara Guerzoni, Camilla Cristalli, Pier Luigi Lollini, Lorena Landuzzi, Sergio Valente, Giulia Stazi, Paola B. Arimondo, Clemens Zwergel
Publikováno v:
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
The identification of new therapeutic strategies against osteosarcoma, the most common primary bone tumor, continues to be a primary goal to improve the outcomes of patients refractory to conventional chemotherapy. Osteosarcoma originates from the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55d5482d55dc2ed43ad6818ec4cbf60
https://hal.archives-ouvertes.fr/hal-02383680
https://hal.archives-ouvertes.fr/hal-02383680
Autor:
Stephen P. Jackson, Mareike Herzog, Alejandra Bruna, Luca Pellegrini, Violeta Serra, Mark J. O'Connor, Zhongwu Lai, Chloé Lescale, Jacqueline J.L. Jacobs, Fengtang Yang, Jonathan Lam, Matylda Sczaniecka-Clift, Abigail Shea, Carlos Caldas, Matthias Ostermaier, Gabriel Balmus, Julia Coates, Wenming Wei, Inge de Krijger, Yaron Galanty, Mukerrem Demir, Ludovic Deriano, Petra Beli, Domenic Pilger, Harveer Dev, Rimma Belotserkovskaya, Alistair Martin, Beiyuan Fu, Ting-Wei Will Chiang, Qian Wu
Publikováno v:
Nature Cell Biology
Nature Cell Biology, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
Nature cell biology
Nature Cell Biology, Nature Publishing Group, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
Nature Cell Biology, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
Nature cell biology
Nature Cell Biology, Nature Publishing Group, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
International audience; BRCA1 deficiencies cause breast, ovarian, prostate and other cancers, and render tumours hypersensitive to poly(ADP-ribose) polymerase (PARP) inhibitors. To understand the resistance mechanisms, we conducted whole-genome CRISP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c03882fb1aad0056e71d15c34e8ed4
https://www.repository.cam.ac.uk/handle/1810/282947
https://www.repository.cam.ac.uk/handle/1810/282947
Autor:
Piperno-Neumann, Sophie, Ray-Coquard, Isabelle, Occean, Bob-Valéry, Laurence, Valérie, Cupissol, Didier, Perrin, Christophe, Penel, Nicolas, Bompas, Emmanuelle, Rios, Maria, Le Cesne, Axel, Italiano, Antoine, Anract, Philippe, De Pinieux, Gonzague, Collard, Olivier, Bertucci, François, Duffaud, Florence, Le Deley, Marie-Cécile, Delaye, Jessy, Brugières, Laurence, Blay, Jean-Yves, Piperno‐Neumann, Sophie, Ray‐Coquard, Isabelle, Occean, Bob‐Valéry, Pinieux, Gonzague, Le Deley, Marie‐Cécile, Blay, Jean‐Yves
Publikováno v:
International Journal of Cancer
International Journal of Cancer, Wiley, 2019, 146 (2), pp.413-423. ⟨10.1002/ijc.32526⟩
International Journal of Cancer, 2019, 146 (2), pp.413-423. ⟨10.1002/ijc.32526⟩
International Journal of Cancer, Wiley, 2019, 146 (2), pp.413-423. ⟨10.1002/ijc.32526⟩
International Journal of Cancer, 2019, 146 (2), pp.413-423. ⟨10.1002/ijc.32526⟩
International audience; In the OS2006 study, patients younger than 18 years were treated with a methotrexate-based regimen (MTX), patients older than 25 years with a doxorubicin-cisplatin-ifosfamide-based regimen (API-AI), whereas patients aged 18-25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e950760137dbb4818b390e785754ca7
https://hal.archives-ouvertes.fr/hal-02530602
https://hal.archives-ouvertes.fr/hal-02530602
Publikováno v:
Indian Journal of Orthopaedics
Indian Journal of Orthopaedics, Vol 52, Iss 1, Pp 87-90 (2018)
Indian Journal of Orthopaedics, Vol 52, Iss 1, Pp 87-90 (2018)
Chondroblastomas are a primary benign cartilaginous tumor that accounts for approximately 1% of all benign bone tumors. Primarily they are treated by curettage. The patient presented 4 years after a successfully treated chondroblastoma (curettage and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39db2c0e769722d22677824134589035
https://pubmed.ncbi.nlm.nih.gov/29416176
https://pubmed.ncbi.nlm.nih.gov/29416176
Autor:
Omer, Natacha
Publikováno v:
Médecine humaine et pathologie. 2015
Background : Optimal phase-II design to evaluate new therapies in osteosarcoma is not defined yet. Objectives : To study the consistency between phase-II clinical trials evaluating new anticancer treatments in osteosarcoma relapse in terms of eligibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e0c074165d0a27bd8fba2ce1e80dd757
https://dumas.ccsd.cnrs.fr/dumas-01318030/document
https://dumas.ccsd.cnrs.fr/dumas-01318030/document
Autor:
Richard H. Wade, Luc Lebeau, Dimitrios A. Skoufias, Robert A. Cross, Yasmina Saoudi, Isabelle Crevel, Salvatore DeBonis, Frank Kozielski, David D. Hackney
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281 (26), pp.17559-69. ⟨10.1074/jbc.M511735200⟩
Journal of Biological Chemistry, 2006, 281 (26), pp.17559-69. ⟨10.1074/jbc.M511735200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281 (26), pp.17559-17569. ⟨10.1074/jbc.M511735200⟩
Journal of Biological Chemistry, 2006, 281 (26), pp.17559-17569. ⟨10.1074/jbc.M511735200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281 (26), pp.17559-69. ⟨10.1074/jbc.M511735200⟩
Journal of Biological Chemistry, 2006, 281 (26), pp.17559-69. ⟨10.1074/jbc.M511735200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281 (26), pp.17559-17569. ⟨10.1074/jbc.M511735200⟩
Journal of Biological Chemistry, 2006, 281 (26), pp.17559-17569. ⟨10.1074/jbc.M511735200⟩
International audience; Human Eg5, responsible for the formation of the bipolar mitotic spindle, has been identified recently as one of the targets of S-trityl-L-cysteine, a potent tumor growth inhibitor in the NCI 60 tumor cell line screen. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0790f52cce3de6bd078d82b6d2e5c4cf
https://doi.org/10.1074/jbc.m511735200
https://doi.org/10.1074/jbc.m511735200
Autor:
Baptist Jammart, Zsolt Ruzsics, Eric J. Kremer, Daniel Henaff, Sigrid Seelmeir, Harald Wodrich, Carolina Segura-Morales, Christopher M. Wiethoff, Olivier Coux
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2010, 6 (3), pp.e1000808. ⟨10.1371/journal.ppat.1000808⟩
PLoS Pathogens, Public Library of Science, 2010, 6 (3), pp.e1000808. 〈10.1371/journal.ppat.1000808〉
PLoS Pathogens, Vol 6, Iss 3, p e1000808 (2010)
PLoS Pathogens, Public Library of Science, 2010, 6 (3), pp.e1000808. ⟨10.1371/journal.ppat.1000808⟩
PLoS Pathogens, Public Library of Science, 2010, 6 (3), pp.e1000808. 〈10.1371/journal.ppat.1000808〉
PLoS Pathogens, Vol 6, Iss 3, p e1000808 (2010)
Viruses use cellular machinery to enter and infect cells. In this study we address the cell entry mechanisms of nonenveloped adenoviruses (Ads). We show that protein VI, an internal capsid protein, is rapidly exposed after cell surface attachment and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82946a3cb04db69f1a1915a12325a56d
https://hal.archives-ouvertes.fr/hal-00523031/document
https://hal.archives-ouvertes.fr/hal-00523031/document
Publikováno v:
J Biol Chem
J Biol Chem, 2002, 277 (18), pp.15697-702. ⟨10.1074/jbc.M112068200⟩
J Biol Chem, 2002, 277 (18), pp.15697-702. ⟨10.1074/jbc.M112068200⟩
Nitric oxide (NO) is an important bioactive molecule involved in a variety of physiological and pathological processes. At the same time, NO is also an inducer of stress signaling, owing to its ability to damage proteins and DNA. NO was reported to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cde471a1df6bad50b1f2cfd4d3e03d
https://doi.org/10.1074/jbc.m112068200
https://doi.org/10.1074/jbc.m112068200
Autor:
Jean Pierre Bazureau, Gaëtan Chicanne, Xavier Fant, Assia Shisheva, Diego Sbrissa, Laurent Meijer, Bernard Payrastre, François Carreaux, Emilie Durieu, Emmanuelle Limanton
Publikováno v:
Molecular Pharmacology
Molecular Pharmacology, 2014, 85 (3), pp.441-50. ⟨10.1124/mol.113.090837⟩
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2014, 85 (3), pp.441-50. ⟨10.1124/mol.113.090837⟩
Molecular Pharmacology, 2014, 85 (3), pp.441-50. ⟨10.1124/mol.113.090837⟩
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2014, 85 (3), pp.441-50. ⟨10.1124/mol.113.090837⟩
International audience; Leucettines, a family of pharmacological inhibitors of dual-specificity tyrosine phosphorylation regulated kinases and cdc-like kinases (CLKs), are currently under investigation for their potential therapeutic application to D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61dd24236c0214b0c3f6c7f147d51b50
https://www.hal.inserm.fr/inserm-01012086
https://www.hal.inserm.fr/inserm-01012086
Autor:
Moriceau, Gatien, Roelofs, Anke, Brion, Régis, Redini, Françoise, Ebetino, Frank, Rogers, Michael, Heymann, Dominique
Publikováno v:
Cancer
Cancer, Wiley, 2012, 118 (3), pp.750-60. ⟨10.1002/cncr.26336⟩
Cancer, Wiley, 2012, 118 (3), pp.750-60. ⟨10.1002/cncr.26336⟩
International audience; BACKGROUND: Osteosarcoma is the most frequent malignant primary bone tumor that occurs mainly in the young, with an incidence peak observed at age 18 years. Both apomine and lovastatin have antitumor activity in a variety of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dcbb08ca006eceba6eca96d76f39526c
https://www.hal.inserm.fr/inserm-00667512
https://www.hal.inserm.fr/inserm-00667512