Eosinophilia predicts poor clinical outcomes in recent-onset arthritis: results from the ESPOIR cohort

Autor: Dewi Guellec, Gabriel J. Tobón, Morgane Milin, Divi Cornec, Gilles Chiocchia, Alain Saraux, Valérie Devauchelle-Pensec, Olivier Vittecocq, Sandrine Jousse-Joulin, Thierry Marhadour

Publikováno v: RMD Open : Rheumatic & Musculoskeletal Diseases
RMD Open : Rheumatic & Musculoskeletal Diseases, BMJ, 2015, 1 (1), pp.e000070. ⟨10.1136/rmdopen-2015-000070⟩
RMD Open : Rheumatic & Musculoskeletal Diseases, EULAR ; BMJ, 2015, 1 (1), pp.e000070. ⟨10.1136/rmdopen-2015-000070⟩
RMD Open

Objectives To determine the prevalence of eosinophilia in patients with recent-onset arthritis suggestive of rheumatoid arthritis (RA) and to describe their features and outcomes. Methods We performed an ancillary study of data from a French prospect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7956efbc6d4f0222c37574b15009f73
https://hal.univ-brest.fr/hal-01559423

Elevated expression of osteopontin may be related to adipose tissue macrophage accumulation and liver steatosis in morbid obesity

Autor: Adeline Bertola, Keith N. Frayn, Yannick Le Marchand-Brustel, Joan Tordjman, Moncef Dahman, S. McQuaid, Albert Tran, Philippe Gual, Karine Clément, Vanessa Deveaux, Jean Gugenheim, Pierre-Michel Huet, Rodolphe Anty, Déborah Rousseau, Sophie Lotersztajn, Abdelilah Wakkach, Stéphanie Bonnafous

Publikováno v: Diabetes
Diabetes, American Diabetes Association, 2009, 58 (1), pp.125-33. ⟨10.2337/db08-0400⟩
Diabetes, American Diabetes Association, 2009, 58 (1), pp.125-33. 〈10.2337/db08-0400〉
Diabetes, 2009, 58 (1), pp.125-33. ⟨10.2337/db08-0400⟩

OBJECTIVE—Osteopontin (OPN) plays an important role in the development of insulin resistance and liver complications in dietary murine models. We aimed to determine the expression pattern of OPN and its receptor CD44 in obese patients and mice acco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c9f48affd8d4ec60c2a9253f9cec47
https://hal.archives-ouvertes.fr/hal-00419058

Disseminated arterial calcification and enhanced myogenic response are associated with abcc6 deficiency in a mouse model of pseudoxanthoma elasticum

Autor: Patrick Lacolley, Daniel Henrion, Carlos Labat, Georges Leftheriotis, Anne Pizard, Y. Mauras, L. Martin, Gilles Kauffenstein, Theo G. M. F. Gorgels, Bertrand Toutain, E. Vessières, O. Le Saux, Linda Grimaud, Y. Le Corre, Arthur A.B. Bergen

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology, 34(5), 1045-1056. Lippincott Williams and Wilkins
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2014, 34 (5), pp.1045-1056. ⟨10.1161/ATVBAHA.113.302943⟩
Arteriosclerosis Thrombosis and Vascular Biology, 34(5), 1045-1056. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis, Thrombosis, and Vascular Biology, 34(5), 1045-56. Lippincott Williams & Wilkins

Objective— Pseudoxanthoma elasticum is an inherited metabolic disorder resulting from ABCC6 gene mutations. It is characterized by progressive calcification and fragmentation of elastic fibers in the skin, retina, and the arterial wall. Despite cal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6aa3adfaef5af07ccf250aebc24a0c
https://pure.amc.nl/en/publications/disseminated-arterial-calcification-and-enhanced-myogenic-response-are-associated-with-abcc6-deficiency-in-a-mouse-model-of-pseudoxanthoma-elasticum(7949fe45-6f9d-400d-89fd-9c195a094b37).html

Osteopontin expression in cardiomyocytes induces dilated cardiomyopathy

Autor: Patricia Reant, Fanny Robbesyn, Thierry Couffinhal, Flavien Charpentier, Karin Klingel, Danièle Daret, Claude Desgranges, Cécile Allières, Victorine Douin, Marie-Ange Renault, Isabelle Belloc, Pierre Dos Santos, Jean-François Arnal, Alain-Pierre Gadeau

Publikováno v: Circulation. Heart failure
Circulation. Heart failure, 2010, 3 (3), pp.431-9. ⟨10.1161/CIRCHEARTFAILURE.109.898114⟩
Circulation. Heart failure, Lippincott Williams & Wilkins, 2010, 3 (3), pp.431-9. ⟨10.1161/CIRCHEARTFAILURE.109.898114⟩

Background— Inflammatory processes play a critical role in myocarditis, dilated cardiomyopathy, and heart failure. The expression of the inflammatory chemokine osteopontin (OPN) is dramatically increased in cardiomyocytes and inflammatory cells dur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8190ea547de3697826592eb079678ed
https://www.hal.inserm.fr/inserm-00504854

Dlx5 drives Runx2 expression and osteogenic differentiation in developing cranial suture mesenchyme

Autor: Martine Bontoux, Stéphanie Mateos, Karine Bollerot, Nicolas Holleville, Anne H. Monsoro-Burq

Publikováno v: Developmental Biology
Developmental Biology, Elsevier, 2007, 304 (2), pp.860-74. ⟨10.1016/j.ydbio.2007.01.003⟩
Developmental Biology, 2007, 304 (2), pp.860-74. ⟨10.1016/j.ydbio.2007.01.003⟩

International audience; Craniofacial bones derive from cephalic neural crest, by endochondral or intramembranous ossification. Here, we address the role of the homeobox transcription factor Dlx5 during the initial steps of calvaria membranous differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f072b421078c9f9d4e71784683d005a
https://pubmed.ncbi.nlm.nih.gov/17335796