TMPRSS2-ERG fusion promotes prostate cancer metastases in bone

Autor: Anne Flourens, Carine Delliaux, Yvan de Launoit, Xavier Leroy, Rachel Deplus, Martine Duterque-Coquillaud, Nathalie Marchand, Nathalie Vanpouille

Publikováno v: Oncotarget
Oncotarget, Impact journals, 2017, 8 (7), pp.11827-11840. ⟨10.18632/oncotarget.14399⟩
Oncotarget, 2017, 8 (7), pp.11827-11840. ⟨10.18632/oncotarget.14399⟩
Oncotarget, 8 (7

Bone metastasis is the major deleterious event in prostate cancer (PCa). TMPRSS2-ERG fusion is one of the most common chromosomic rearrangements in PCa. However, its implication in bone metastasis development is still unclear. Since bone metastasis s

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https://hal.archives-ouvertes.fr/hal-02391621/file/TMPRSS2-ERG_fusion_promotes_prostate.pdf