Výsledky vyhledávání - "MESH: Oligosaccharides"

Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase

Autor: Emeline Richard, Véronique Roig-Zamboni, Hugues Lortat-Jacob, Firas Fadel, Jérôme Hénault, Adeline Goulet, Christine Le Narvor, Yves Bourne, David Bonnaffé, Vincent Delauzun, C. Debarnot, Yoan R. Monneau, Bernard Priem, Romain R. Vivès

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (14), pp.6760-6765. ⟨10.1073/pnas.1818333116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, pp.201818333. ⟨10.1073/pnas.1818333116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (14), pp.6760-6765. ⟨10.1073/pnas.1818333116⟩

Heparan sulfate (HS) is a linear, complex polysaccharide that modulates the biological activities of proteins through binding sites made by a series of Golgi-localized enzymes. Of these, glucuronyl C5-epimerase (Glce) catalyzes C5-epimerization of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f534dfa4e1c1196a83a65edeecbf515
https://hal-amu.archives-ouvertes.fr/hal-02339215/document

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Overview of the Structure–Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi

Autor: Pierre Rougé, Els J.M. Van Damme, Yves Bourne, Annick Barre

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2019, Protein–Carbohydrate Interactions: Structure–Function Relationships, 20 (2), pp.254. ⟨10.3390/ijms20020254⟩
International Journal of Molecular Sciences, MDPI, 2019, Protein–Carbohydrate Interactions: Structure–Function Relationships, 20 (2), pp.254. ⟨10.3390/ijms20020254⟩
International Journal of Molecular Sciences, Vol 20, Iss 2, p 254 (2019)
International Journal of Molecular Sciences, MDPI, 2019, 20 (2), pp.254. ⟨10.3390/ijms20020254⟩
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

International audience; To date, a number of mannose-binding lectins have been isolated and characterized from plants and fungi. These proteins are composed of different structural scaffold structures which harbor a single or multiple carbohydrate-bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982468c7fc07d8555669c3f1710741e1
https://hal-amu.archives-ouvertes.fr/hal-02388775/document

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Organization of GPI-anchored proteins at the cell surface and its physiopathological relevance

Autor: Simona Paladino, Stéphanie Lebreton, Chiara Zurzolo

Publikováno v: Critical Reviews in Biochemistry and Molecular Biology
Critical Reviews in Biochemistry and Molecular Biology, Taylor & Francis, 2018, 53 (4), pp.403-419. ⟨10.1080/10409238.2018.1485627⟩
Critical Reviews in Biochemistry and Molecular Biology, 2018, 53 (4), pp.403-419. ⟨10.1080/10409238.2018.1485627⟩

International audience; Glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) are a class of proteins attached to the extracellular leaflet of the plasma membrane via a post-translational modification, the glycolipid anchor. The presence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07239b7e06aa62d73c0a7254c40ac7b0
https://hal-pasteur.archives-ouvertes.fr/pasteur-02263637

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Maternal exposure to GOS/inulin mixture prevents food allergies and promotes tolerance in offspring in mice

Autor: Michel Neunlist, Philippe Aubert, Laure Castan, Faouzi Braza, Julie Chesné, Antoine Magnan, Marie Bodinier, Grégory Bouchaud

Publikováno v: Allergy
Allergy, Wiley, 2016, Equipe 6, 71 (1), pp.68--76. ⟨10.1111/all.12777⟩
Allergy, 2016, Equipe 6, 71 (1), pp.68--76. ⟨10.1111/all.12777⟩

International audience; BACKGROUND: Food allergies affect 4-8% of children and are constantly on the rise, thus making allergies a timely issue. Most importantly, prevention strategies are nonexistent, and current therapeutic strategies have limited

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888394305e5ea528aa2f295a638955e8
https://hal.archives-ouvertes.fr/hal-01831748

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Idraparinux versus standard therapy for venous thromboembolic disease

Autor: Renseigné, Non, Buller, Harry R, Cohen, Ander T, Davidson, Bruce, Decousus, Hervé, Gallus, Alex S, Gent, Michael, Pillion, Gerard, Piovella, Franco, Prins, Martin H, Raskob, Gary E

Publikováno v: New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2007, 357 (11), pp.1094-104. ⟨10.1056/NEJMoa064247⟩
New England journal of medicine, 357(11), 1094-1104. Massachussetts Medical Society
New England Journal of Medicine, 2007, 357 (11), pp.1094-104. ⟨10.1056/NEJMoa064247⟩

International audience; BACKGROUND: Venous thromboembolism is treated with unfractionated heparin or low-molecular-weight heparin, followed by a vitamin K antagonist. We investigated the potential use of idraparinux, a long-acting inhibitor of activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3534c427bde9fdc0b85194fdb0d7ec9
https://doi.org/10.1056/nejmoa064247

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SUN proteins belong to a novel family of β-(1,3)-glucan-modifying enzymes involved in fungal morphogenesis

Autor: Christine Schmitt, Christophe d'Enfert, Audrey Nesseir, Anne Beauvais, Patrick England, Vishukumar Aimanianda, Rémi Beau, Arnaud Firon, Marie-Christine Prévost, Amandine Gastebois, Sophie Bachellier-Bassi, Jean-Paul Latgé, Isabelle Mouyna

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, 288 (19), pp.13387-96. ⟨10.1074/jbc.M112.440172⟩
Journal of Biological Chemistry, 2013, 288 (19), pp.13387-96. ⟨10.1074/jbc.M112.440172⟩
Journal of Biological Chemistry 19 (288), 13387-13396. (2013)
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, 288 (19), pp.13387-13396. 〈10.1074/jbc.M112.440172〉

International audience; BACKGROUND:SUN proteins are involved in yeast morphogenesis, but their function is unknown.RESULTS:SUN protein plays a role in the Aspergillus fumigatus morphogenesis. Biochemical properties of recombinant SUN proteins were el

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6f9df74669906a54aa3de73b481161
https://hal-pasteur.archives-ouvertes.fr/pasteur-01522918

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Synthesis of a Pentasaccharide and Neoglycoconjugates Related to Fungal α-(1→3)-Glucan and Their Use in the Generation of Antibodies to Trace Aspergillus fumigatus Cell Wall

Autor: Maria V. Orekhova, Bozhena S. Komarova, Vishukumar Aimanianda, Rémi Beau, Yury E. Tsvetkov, Jean-Paul Latgé, Nikolay E. Nifantiev

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2015, 21 (3), pp.1029-1035. ⟨10.1002/chem.201404770⟩
Chemistry-A European Journal, 2015, 21 (3), pp.1029-1035. ⟨10.1002/chem.201404770⟩

International audience; 3-Aminopropyl α-(1→3)-pentaglucoside, a fragment of α-(1→3)-glucan of the cell wall of Aspergillus fumigatus, has been synthesized in a blockwise approach. The application of mono- and disaccharide N-phenyltrifluoroaceti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122cc786e162494f22b62c67574e0824
https://hal-pasteur.archives-ouvertes.fr/pasteur-02515848

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Pectin-Derived Acidic Oligosaccharides Improve the Outcome of Pseudomonas aeruginosa Lung Infection in C57BL/6 Mice

Autor: Bernd Carsten Stahl, Jean-Luc Desseyn, Marie-Odile Husson, Frédéric Gottrand, Henry Bernard, Nana Bartke

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2015, 10 (11), pp.e0139686. ⟨10.1371/journal.pone.0139686⟩
PLoS ONE, Vol 10, Iss 11, p e0139686 (2015)
PLoS ONE, 2015, 10 (11), pp.e0139686. ⟨10.1371/journal.pone.0139686⟩

International audience; The administration of prebiotics as oligosaccharides (OS), by acting on intestinal microbiota, could modulate the immune and inflammatory response and represent a new strategy to improve the outcome of bacterial infection. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e8d996f4d3641c4c4d72187eaa8670
https://hal.univ-lille.fr/hal-02178904

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Molecular Basis for Different Levels of tet(M) Expression in Streptococcus pneumoniae Clinical Isolates

Autor: Laurent Gutmann, Sophie Grondin, Arnaud Firon, Claire Poyart, Emmanuelle Varon, Isabelle Podglajen, Patrick Grohs, Patrick Trieu-Cuot

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 2012, 56 (10), pp.5040-5045. ⟨10.1128/aac.00939-12⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2012, 56 (10), pp.5040-5045. ⟨10.1128/aac.00939-12⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2012, 56 (10), pp.5040-5045. 〈10.1128/aac.00939-12〉

Seventy-four unrelated clinical isolates of Streptococcus pneumoniae harboring the tet (M) gene were studied. Seven strains with low tetracycline (Tc) MICs (0.25 to 0.5 μg/ml) were found to harbor truncated tet (M) alleles that were inactivated by d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34a491627e8e386a99479c5ee870071
https://hal-pasteur.archives-ouvertes.fr/pasteur-01300171

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CGTase-Catalysed cis -Glucosylation of L -Rhamnosides for the Preparation of Shigella flexneri 2a and 3a Haptens

Autor: Hugues Driguez, Carole Urbach, Catherine Guerreiro, Sami Halila, Laurence A. Mulard, Sylvie Armand

Publikováno v: ChemBioChem
ChemBioChem, 2014, 15 (2), pp.293-300. ⟨10.1002/cbic.201300597⟩
ChemBioChem, Wiley-VCH Verlag, 2014, 15 (2), pp.293-300. ⟨10.1002/cbic.201300597⟩

International audience; We report the enzymatic synthesis of α-D-glucopyranosyl-(1→4)-α-L-rhamnopyranoside and α-D-glucopyranosyl-(1→3)-α-L-rhamnopyranoside by using a wild-type transglucosidase in combination with glucoamylase and glucose ox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba300b821589796081ad79b816c4201
https://hal-pasteur.archives-ouvertes.fr/pasteur-02043361

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