Teriflunomide Promotes Oligodendroglial 8,9-Unsaturated Sterol Accumulation and CNS Remyelination

Autor: Brahim Nait Oumesmar, Catherine Lubetzki, Corinne Bachelin, Bruno Stankoff, Marie-Stéphane Aigrot, Elodie Martin, Bernard Zalc, Foudil Lamari

Publikováno v: Neurology Neuroimmunology & Neuroinflammation
Neurology Neuroimmunology & Neuroinflammation, 2021, 8 (6), pp.e1091. ⟨10.1212/nxi.0000000000001091⟩
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3

Background and ObjectivesTo test whether low concentrations of teriflunomide (TF) could promote remyelination, we investigate the effect of TF on oligodendrocyte in culture and on remyelination in vivo in 2 demyelinating models.MethodsThe effect of T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb06d6f79a5aaeb12d7edbb15113fa4
https://doi.org/10.1212/nxi.0000000000001091