Výsledky vyhledávání - "MESH: O Antigens"

Leptospiral LPS escapes mouse TLR4 internalization and TRIF‑associated antimicrobial responses through O antigen and associated lipoproteins

Autor: Ignacio Santecchia, Ivo G. Boneca, Frédérique Vernel-Pauillac, Ben Adler, Delphine Bonhomme, Gerald L. Murray, Martine Caroff, Pierre Germon, Catherine Werts

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2020, 16 (8), pp.e1008639. ⟨10.1371/journal.ppat.1008639⟩
PLoS Pathogens, Vol 16, Iss 12, p e1009173 (2020)
PLoS Pathogens, 2020, 16 (8), pp.e1008639. ⟨10.1371/journal.ppat.1008639⟩
PLoS Pathogens, Vol 16, Iss 8, p e1008639 (2020)

Leptospirosis is a worldwide re-emerging zoonosis caused by pathogenic Leptospira spp. All vertebrate species can be infected; humans are sensitive hosts whereas other species, such as rodents, may become long-term renal carrier reservoirs. Upon infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f13a49d5e8b035c7e56a6269ac9a0d7
https://hal.inrae.fr/hal-02949538

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Detailed Investigation of the Immunodominant Role of O-Antigen Stoichiometric O-Acetylation as Revealed by Chemical Synthesis, Immunochemistry, Solution Conformation and STD-NMR Spectroscopy forShigella flexneri 3a

Autor: Laurence A. Mulard, Ana Ardá, F. Javier Cañada, Armelle Phalipon, Pilar Blasco, Françoise Thouron, Catherine Guerreiro, Jesús Jiménez-Barbero, Farida Nato, Sylvie Dartevelle, Julien Boutet

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, 2016, 22 (31), pp.10892-10911. ⟨10.1002/chem.201600567⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2016, 22 (31), pp.10892-10911. ⟨10.1002/chem.201600567⟩

International audience; Shigella flexneri 3a causes bacillary dysentery. Its O-antigen has the {2)-[α-d-Glcp-(1→3)]-α-l-Rhap-(1→2)-α-l-Rhap-(1→3)-[Ac→2]-α-l-Rhap-(1→3)-[Ac→6]≈40 % -β-d-GlcpNAc-(1→} ([(E)ABAc CAc D]) repeating uni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6b2b38ddd316d00de09b2b30e93ec3
https://doi.org/10.1002/chem.201600567

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Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens

Autor: Kunstmann, Sonja, Scheidt, Tom, Buchwald, Saskia, Helm, Alexandra, Mulard, Laurence A., Fruth, Angelika, Barbirz, Stefanie

Publikováno v: Viruses
Viruses, MDPI, 2018, 10 (8), pp.431. ⟨10.3390/v10080431⟩
Viruses, Vol 10, Iss 8, p 431 (2018)
Viruses, 2018, 10 (8), pp.431. ⟨10.3390/v10080431⟩

International audience; Bacteriophage research is gaining more importance due to increasing antibiotic resistance. However, for treatment with bacteriophages, diagnostics have to be improved. Bacteriophages carry adhesion proteins, which bind to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b73ac4f22e36f25a48e566dca1a5cb4b
https://hal-pasteur.archives-ouvertes.fr/pasteur-02043351/file/viruses-10-00431.pdf

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Genomic characterization of environmental Pseudomonas aeruginosa isolated from dental unit waterlines revealed the insertion sequence ISPa11 as a chaotropic element

Autor: Brian Boyle, Antony T. Vincent, Marie-Christine Groleau, Steve J. Charette, Luca Freschi, Irena Kukavica-Ibrulj, Fabrice Jean-Pierre, Julie Jeukens, Eric Déziel, Jean Barbeau, Annie Leduc, Roger C. Levesque, Jean-Guillaume Emond-Rheault

Publikováno v: FEMS Microbiology Ecology
FEMS Microbiology Ecology, Wiley-Blackwell, 2017, 93 (9), ⟨10.1093/femsec/fix106⟩

International audience; The bacterium Pseudomonas aeruginosa is well known to have a remarkable adaptive capacity allowing it to colonise many environments. A recent study on environmental isolates from dental unit waterlines (DUWLs) hinted at a gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cecc1d5fb4c9415a89053df1e1fe012c
https://doi.org/10.1093/femsec/fix106

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Comparison of multiplex PCR with serogrouping and PCR-RFLP of fliC gene for the detection of enteropathogenic Escherichia coli (EPEC)

Autor: Mana Oloomi, Anis Jafari, Amir Dashti, Saeid Bouzari, Mohammad Mehdi Aslani

Publikováno v: Brazilian Journal of Infectious Diseases, Vol 15, Iss 4, Pp 365-369
Brazilian Journal of Infectious Diseases, Volume: 15, Issue: 4, Pages: 365-369, Published: AUG 2011
Brazilian Journal of Infectious Diseases, Vol 15, Iss 4, Pp 365-369 (2011)
Brazilian Journal of Infectious Diseases
Brazilian Journal of Infectious Diseases, Elsevier, 2011, 15 (4), pp.365-369. ⟨10.1016/S1413-8670(11)70206-9⟩
Brazilian Journal of Infectious Diseases v.15 n.4 2011
Brazilian Society of Infectious Diseases (BSID)
instacron:BSID

Enteropathogenic Escherichia coli (EPEC) comprise one of the six categories of diarrhoeagenic E. coli (DEC). EPEC is subgrouped into typical (tEPEC) and atypical (aEPEC). The identification of DEC cannot be based only on cultural and biochemical crit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3956125a39a586abbfb3b11b917b0785
https://doi.org/10.1590/s1413-86702011000400011

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Optimization of Virulence Functions Through Glucosylation of Shigella LPS

Autor: Muriel Delepierre, Nicholas P. West, Philippe J. Sansonetti, Joëlle Mounier, Stéphanie Guadagnini, Ada Prochnicka-Chalufour, Christoph M. Tang, Rachel M. Exley, Myriam Tanguy, Claude Parsot, Marie-Christine Prévost

Publikováno v: Science
Science, American Association for the Advancement of Science, 2005, 307 (5713), pp.1313-7. ⟨10.1126/science.1108472⟩
Science, 2005, 307 (5713), pp.1313-7. ⟨10.1126/science.1108472⟩

Shigella , the leading cause of bacillary dysentery, uses a type III secretion system (TTSS) to inject proteins into human cells, leading to bacterial invasion and a vigorous inflammatory response. The bacterium is protected against the response by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758205c8ca8c4134123890bd5a0c4d4e
https://doi.org/10.1126/science.1108472

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Design of alpha-transglucosidases of controlled specificity for programmed chemoenzymatic synthesis of antigenic oligosaccharides

Autor: Karine Descroix, Laurence A. Mulard, Isabelle André, Claire Moulis, Elise Champion, Magali Remaud-Simeon, Sandrine Morel, Pierre Monsan, Julien Boutet

Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, 2009, 131 (21), pp.7379-89. ⟨10.1021/ja900183h⟩
Journal of the American Chemical Society, American Chemical Society, 2009, 131 (21), pp.7379-89. ⟨10.1021/ja900183h⟩

International audience; Combined with chemical synthesis, the use of biocatalysts holds great potential to open the way to novel molecular diversity. We report in vitro chemoenzymatic pathways that, for the first time, take advantage of enzyme engine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14419a0ab9db208c0effd8846bfe8033
https://hal.science/hal-00414248

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Structural mimicry of O-antigen by a peptide revealed in a complex with an antibody raised against Shigella flexneri serotype 2a

Autor: Muriel Delepierre, Armelle Phalipon, Brigitte Vulliez-Le Normand, Frederick Saul, François-Xavier Theillet, Andrej Weintraub, Sylviane Hoos, Graham A. Bentley, Franco Felici, Laurence A. Mulard

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2009, 388 (4), pp.839-50. ⟨10.1016/j.jmb.2009.03.057⟩
Journal of Molecular Biology, 2009, 388 (4), pp.839-50. ⟨10.1016/j.jmb.2009.03.057⟩

International audience; The use of carbohydrate-mimicking peptides to induce immune responses against surface polysaccharides of pathogenic bacteria offers a novel approach to vaccine development. Factors governing antigenic and immunogenic mimicry,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1db148d86db9bcd0eae4ea3bc8ef25f
https://hal.archives-ouvertes.fr/hal-00414251

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Efficient synthesis of six tri- to hexasaccharide fragments of Shigella flexneri serotypes 3a and/or X O-antigen, including a study on acceptors containing N-trichloroacetylglucosamine versus N-acetylglucosamine

Autor: Catherine Guerreiro, Julien Boutet, Laurence A. Mulard

Publikováno v: Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2009, 74 (7), pp.2651-70. ⟨10.1021/jo802127z⟩
Journal of Organic Chemistry, 2009, 74 (7), pp.2651-70. ⟨10.1021/jo802127z⟩

International audience; Six tri- to hexasaccharide fragments of the {2)-[alpha-D-Glcp-(1-->3)]-alpha-L-Rhap-(1-->2)-alpha-L-Rhap-(1-->3)-[Ac-->2]-alpha-L-Rhap-(1-->3)-beta-D-GlcpNAc-(1-->}(n) polymer ([(E)AB(Ac)CD](n)) were synthesized as their propy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12401ae45934135466e905df2def8058
https://pubmed.ncbi.nlm.nih.gov/19278208

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