Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration

Autor: Matysiak, Julien, Lesbats, Paul, Mauro, Eric, Lapaillerie, Delphine, Dupuy, Jean-William, Lopez, Angelica P., Benleulmi, Mohamed Salah, Calmels, Christina, Andreola, Marie-Line, Ruff, Marc, Llano, Manuel, Delelis, Olivier, Lavigne, Marc, Parissi, Vincent

Publikováno v: Retrovirology, Vol 14, Iss 1, Pp 1-20 (2017)
Retrovirology
Retrovirology, 2017, 14 (1), pp.39. ⟨10.1186/s12977-017-0363-4⟩

Background Insertion of retroviral genome DNA occurs in the chromatin of the host cell. This step is modulated by chromatin structure as nucleosomes compaction was shown to prevent HIV-1 integration and chromatin remodeling has been reported to affec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9ec8c2bdc26460a5c28f2a5639693c43
http://link.springer.com/article/10.1186/s12977-017-0363-4

Regulating retrotransposon activity through the use of alternative transcription start sites

Autor: Mette Boyd, Catherine Schurra, Jenna Persson, Benoit Arcangioli, Agata Smialowska, Jette Bornholdt, Babett Steglich, Robin Andersson, Albin Sandelin, Karl Ekwall, Olaf Nielsen

Publikováno v: EMBO Reports
EMBO Reports, 2016, 17 (5), pp.753-768. ⟨10.15252/embr.201541866⟩
Persson, J, Steglich, B, Smialowska, A, Boyd, M, Lange, J B, Andersson, R, Schurra, C, Arcangioli, B, Sandelin, A G, Nielsen, O & Ekwall, K 2016, ' Regulating retrotransposon activity through the use of alternative transcription start sites ', E M B O Reports, vol. 17, no. 5, pp. 753-768 . https://doi.org/10.15252/embr.201541866
ResearcherID
EMBO Reports, EMBO Press, 2016, 17 (5), pp.753-768. ⟨10.15252/embr.201541866⟩
EMBO reports

International audience; Retrotransposons, the ancestors of retroviruses, have the potential for gene disruption and genomic takeover if not kept in check. Paradoxically, although host cells repress these elements by multiple mechanisms, they are tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d50bd7e5b27872dffa8cce291e5fcfa
https://doi.org/10.15252/embr.201541866

Pathogenic anti-nucleosome antibodies

Autor: Sylviane Muller, Angela Tincani, Pier Luigi Meroni, Jürgen Dieker

Publikováno v: Lupus
Lupus, SAGE Publications, 2008, 17 (5), pp.431-6. ⟨10.1177/0961203308090030⟩

There is increasing evidence that in systemic lupus erythematosus, nucleosomes, the basic chromatin component, represent both a driving immunogen and a major in vivo target for antibodies. Either a disturbed apoptosis or a reduced clearance of apopto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9769fb5c4568b7ac95116602984c3d17
https://doi.org/10.1177/0961203308090030

The NH2 Tail of the Novel Histone Variant H2BFWT Exhibits Properties Distinct from Conventional H2B with Respect to the Assembly of Mitotic Chromosomes

Autor: Ali Hamiche, Philippe Bouvet, Thierry Gautier, Stefan Dimitrov, Gaelh Ouengue Mbele, Véronique Gerson, Matthieu Boulard, Dimitar Angelov

Publikováno v: Molecular and Cellular Biology
Molecular and Cellular Biology, 2006, 26, pp.1518-26. ⟨10.1128/MCB.26.4.1518-1526.2006⟩
Molecular and Cellular Biology, American Society for Microbiology, 2006, 26, pp.1518-26. ⟨10.1128/MCB.26.4.1518-1526.2006⟩

International audience; We have studied the functional and structural properties of nucleosomes reconstituted with H2BFWT, a recently identified putative histone variant of the H2B family with totally unknown function. We show that H2BFWT can replace

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefe96d2f2bbf4adef482a2975cc10d3
https://doi.org/10.1128/mcb.26.4.1518-1526.2006

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

Autor: Dolores Vaira, Georges Herbein, Stéphane De Wit, Jean-Stéphane Gatot, Sophie Reuse, Solène Poutrel, Yvan de Launoit, Miriam Calao, Olivier Lambotte, Carine Van Lint, Caroline Vanhulle, Thomas Cherrier, Christine Rouzioux, Jacques Piette, Kabamba Kabeya, Vincent Quivy, Olivier Rohr, Michel Moutschen, Dominique Demonte, Aurélia Lamine, Arsène Burny, Véronique Avettand, Nathan Clumeck, Valérie Martinelli, Yves Collette, Emmanuelle Veithen, Allan Guiguen

Publikováno v: PloS one, 4 (6
PLoS ONE
PLoS ONE, Vol 4, Iss 6, p e6093 (2009)
PLoS ONE, Public Library of Science, 2009, 4 (6), pp.e6093. 〈10.1371/journal.pone.0006093〉
PLoS ONE, Public Library of Science, 2009, 4 (6), pp.e6093. ⟨10.1371/journal.pone.0006093⟩

The persistence of transcriptionally silent but replication-competent HIV-1 reservoirs in Highly Active Anti-Retroviral Therapy (HAART)-treated infected individuals, represents a major hurdle to virus eradication. Activation of HIV-1 gene expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f82fc5918a8eda67432f871e8e824cf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/51760