Defect in the nuclear pore membrane glycoprotein 210-like gene is associated with extreme uncondensed sperm nuclear chromatin and male infertility: a case report

Autor: Fabrice Lopez, Philippe Bulet, Nicolas Thierry-Mieg, Virginie Tassistro, Caroline Cazin, Pierre F. Ray, Karim Arafah, Zine-Eddine Kherraf, Anderson Loundou, Christophe Arnoult, Marie Roberte Guichaoua

Publikováno v: Human Reproduction
Human Reproduction, Oxford University Press (OUP), 2021, 36 (3), pp.693-701. ⟨10.1093/humrep/deaa329⟩
Human Reproduction, 2021, 36 (3), pp.693-701. ⟨10.1093/humrep/deaa329⟩

After the two meiotic divisions, haploid round spermatids undergo dramatic changes to become mature spermatozoa. One of the main transformations consists of compacting the cell nucleus to confer the sperm its remarkable hydrodynamic property and to p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8e31c537fd1dac0ce67172ebeb364f
https://hal.archives-ouvertes.fr/hal-02985525

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells

Autor: Owen Pornillos, Luca Petiti, Ingrid Cifola, Cindy Buffone, Barbie K. Ganser-Pornillos, Francesca Di Nunzio, Stella Frabetti, Alicia Martinez-Lopez, Thomas Fricke, Felipe Diaz-Griffero, Marco Severgnini, Kaneil K. Zadrozny, Silvana Opp, Katarzyna Skorupka

Publikováno v: Journal of virology (Online) 92 (2018): e00648-18. doi:10.1128/JVI.00648-18
info:cnr-pdr/source/autori:Cindy Buffone1, Alicia Martinez-Lopez1, Thomas Fricke1, Silvana Opp1, Marco Severgnini2, Ingrid Cifola2, Luca Petiti2, Stella Frabetti3, Katarzyna Skorupka4, Kaneil K. Zadrozny4, Barbie K. Ganser-Pornillos4, Owen Pornillos4, Francesca Di Nunzio3+ and Felipe Diaz-Griffero1+/titolo:Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Non-dividing Cells/doi:10.1128%2FJVI.00648-18/rivista:Journal of virology (Online)/anno:2018/pagina_da:e00648-18/pagina_a:/intervallo_pagine:e00648-18/volume:92
Journal of Virology
Journal of Virology, American Society for Microbiology, 2018, 92 (19), pp.e00648-18. ⟨10.1128/JVI.00648-18⟩
Journal of Virology, 2018, 92 (19), pp.e00648-18. ⟨10.1128/JVI.00648-18⟩

International audience; Human immunodeficiency virus type 1 (HIV-1) displays the unique ability to infect nondividing cells. The capsid of HIV-1 is the viral determinant for viral nuclear import. To understand the cellular factors involved in the abi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6978efd22d982ea79c9988aa4f57b2f9
https://europepmc.org/articles/PMC6146805/

Structural and Functional Studies of Nup107/Nup133 Interaction and Its Implications for the Architecture of the Nuclear Pore Complex

Autor: Sandra Jeudy, Thomas U. Schwartz, Ian C. Berke, Thomas Boehmer

Publikováno v: Molecular Cell
Molecular Cell, Elsevier, 2008, 30 (6), pp.721-731. ⟨10.1016/j.molcel.2008.04.022⟩
Molecular Cell, 2008, 30 (6), pp.721-731. ⟨10.1016/j.molcel.2008.04.022⟩

Nuclear pore complexes (NPCs) are 40–60 MDa protein assemblies embedded in the nuclear envelope of eukaryotic cells. NPCs exclusively mediate all transport between cytoplasm and nucleus. The nucleoporins that build the NPC are arranged in a stable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86819c965d10bf4317b5ce660a9a08af

Chromatin organization at the nuclear pore favours HIV replication

Autor: Pierre Charneau, Christophe Zimmer, Philippe Souque, Felipe Diaz-Griffero, Danilo Pellin, Ermanno Rizzi, Clelia Di Serio, Mickaël Lelek, Thomas Fricke, Marco Severgnini, Nicoletta Casartelli, Francesca Di Nunzio

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2015, 6, pp.6483. ⟨10.1038/ncomms7483⟩
Nature Communications, 2015, 6, pp.6483. ⟨10.1038/ncomms7483⟩
Nature communications 6 (2015). doi:10.1038/ncomms7483
info:cnr-pdr/source/autori:Lelek, Mickaël; Casartelli, Nicoletta; Pellin, Danilo; Rizzi, Ermanno; Souque, Philippe; Severgnini, Marco; Di Serio, Clelia; Fricke, Thomas; Diaz-Griffero, Felipe; Zimmer, Christophe; Charneau, Pierre; Di Nunzio, Francesca/titolo:Chromatin organization at the nuclear pore favours HIV replication/doi:10.1038%2Fncomms7483/rivista:Nature communications/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume:6

The molecular mechanisms that allow HIV to integrate into particular sites of the host genome are poorly understood. Here we tested if the nuclear pore complex (NPC) facilitates the targeting of HIV integration by acting on chromatin topology. We sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c621fd021a5096d51bdccfaae7d5ae
https://hal-pasteur.archives-ouvertes.fr/pasteur-01536149

The Ribonucleotide Reductase R1 Subunits of Herpes Simplex Virus 1 and 2 Protect Cells against Poly(I · C)-Induced Apoptosis

Autor: Florent Dufour, Angela Pearson, Yves Langelier, Luc Bertrand, Nathalie Grandvaux

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2011, 85 (17), pp.8689-701. ⟨10.1128/JVI.00362-11⟩

We recently provided evidence that the ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 (HSV-1 and -2) protect cells against tumor necrosis factor alpha- and Fas ligand-induced apoptosis by interacting with caspase 8. Double

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf3002434d6a57e3fc9081293940de6
https://doi.org/10.1128/jvi.00362-11