Zobrazeno 1 - 10
of 13
pro vyhledávání: '"MESH: Nod2 Signaling Adaptor Protein"'
Autor:
Normand, Sylvain, Waldschmitt, Nadine, Neerincx, Andreas, Martinez-Torres, Ruben Julio, Chauvin, Camille, Couturier-Maillard, Aurelie, Boulard, Olivier, Cobret, Laetitia, Awad, Fawaz, Huot, Ludovic, Ribeiro-Ribeiro, Andre, Lautz, Katja, Ruez, Richard, Delacre, Myriam, Bondu, Clovis, Guilliams, Martin, Scott, Charlotte, Segal, Anthony, Amselem, Serge, Hot, David, Karabina, Sonia, Bohn, Erwin, Ryffel, Bernhard, Poulin, Lionel F, Kufer, Thomas A, Chamaillard, Mathias
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications, 2018, 9, pp.5338. ⟨10.1038/s41467-018-07750-5⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-07750-5⟩
Nature Communications, Nature Publishing Group, 2018, 9, pp.5338. ⟨10.1038/s41467-018-07750-5⟩
NATURE COMMUNICATIONS
Nature Communications
Nature Communications, 2018, 9, pp.5338. ⟨10.1038/s41467-018-07750-5⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-07750-5⟩
Nature Communications, Nature Publishing Group, 2018, 9, pp.5338. ⟨10.1038/s41467-018-07750-5⟩
NATURE COMMUNICATIONS
Mutations in the nucleotide-binding oligomerization domain protein 12 (NLRP12) cause recurrent episodes of serosal inflammation. Here we show that NLRP12 efficiently sequesters HSP90 and promotes K48-linked ubiquitination and degradation of NOD2 in r
Autor:
Jeremy Goc, Gregory G. Putzel, Hiroki Kabata, Judith R. Kelsen, Manish A. Shah, Endi K. Santosa, Gérard Eberl, Gregory F. Sonnenberg, Coco Chu, Kendall A. Smith, Fei Teng, Lei Zhou, Robbyn Sockolow, Robert N. Baldassano, Nicholas J. Bessman, Eric Vivier
Publikováno v:
Nature
Nature, 2019, 568 (7752), pp.405-409. ⟨10.1038/s41586-019-1082-x⟩
Nature, Nature Publishing Group, 2019, 568 (7752), pp.405-409. ⟨10.1038/s41586-019-1082-x⟩
Nature, 2019, 568 (7752), pp.405-409. ⟨10.1038/s41586-019-1082-x⟩
Nature, Nature Publishing Group, 2019, 568 (7752), pp.405-409. ⟨10.1038/s41586-019-1082-x⟩
International audience; Interleukin (IL)-2 is a pleiotropic cytokine that is necessary to prevent chronic inflammation in the gastrointestinal tract 1-4. The protective effects of IL-2 involve the generation, maintenance and function of regulatory T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b74b95cc1414507458227043fc6212
https://hal-pasteur.archives-ouvertes.fr/pasteur-03258606
https://hal-pasteur.archives-ouvertes.fr/pasteur-03258606
Autor:
David Skurnik, Noah Zaitlen, Eric J. Tchetgen Tchetgen, Jacques Cosnes, Harry Sokol, Laurent Beaugerie, Dan Knights, Hugues Aschard, Vincent Laville, Rinse K. Weersma, Philippe Seksik, Ramnik J. Xavier, Mark S. Silverberg, Floris Imhann
Publikováno v:
PLoS Genetics
PLoS Genetics, 2019, 15 (3), pp.e1008018. ⟨10.1371/journal.pgen.1008018⟩
PLoS genetics, 15(3):e1008018. PUBLIC LIBRARY SCIENCE
PLoS Genetics, Vol 15, Iss 3, p e1008018 (2019)
PLoS Genetics, Public Library of Science, 2019, 15 (3), pp.e1008018. ⟨10.1371/journal.pgen.1008018⟩
PLoS Genetics, 2019, 15 (3), pp.e1008018. ⟨10.1371/journal.pgen.1008018⟩
PLoS genetics, 15(3):e1008018. PUBLIC LIBRARY SCIENCE
PLoS Genetics, Vol 15, Iss 3, p e1008018 (2019)
PLoS Genetics, Public Library of Science, 2019, 15 (3), pp.e1008018. ⟨10.1371/journal.pgen.1008018⟩
Several bacteria in the gut microbiota have been shown to be associated with inflammatory bowel disease (IBD), and dozens of IBD genetic variants have been identified in genome-wide association studies. However, the role of the microbiota in the etio
Autor:
Jérémy Brunet, Erwan Pernet, Lhousseine Touqui, Laurent Guillemot, Michel Chignard, Yongzheng Wu
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (11), pp.5312-5319. ⟨10.4049/jimmunol.1402665⟩
Journal of Immunology, 2015, 194 (11), pp.5312-5319. ⟨10.4049/jimmunol.1402665⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (11), pp.5312-5319. ⟨10.4049/jimmunol.1402665⟩
Journal of Immunology, 2015, 194 (11), pp.5312-5319. ⟨10.4049/jimmunol.1402665⟩
Staphylococcus aureus is a common cause of bacterial infections in respiratory diseases. It secretes molecules to dampen host immunity, and the recently identified adenosine is one of these molecules. The type IIA secretory phospholipase A2 (sPLA2-II
Autor:
Ratet, Gwenn, Santecchia, Ignacio, Fanton d'Andon, Martine, Vernel-Pauillac, Frédérique, Wheeler, Richard, Lenormand, Pascal, Fischer, Frédéric, Lechat, Pierre, Haake, David, Picardeau, Mathieu, Boneca, Ivo, Werts, Catherine
Publikováno v:
PLoS pathogens, vol 13, iss 12
PLoS Pathogens
PLoS Pathogens, 2017, 13 (12), pp.e1006725. ⟨10.1371/journal.ppat.1006725⟩
PLoS Pathogens, Vol 13, Iss 12, p e1006725 (2017)
PLoS Pathogens, Public Library of Science, 2017, 13 (12), pp.e1006725. ⟨10.1371/journal.ppat.1006725⟩
PLoS Pathogens
PLoS Pathogens, 2017, 13 (12), pp.e1006725. ⟨10.1371/journal.ppat.1006725⟩
PLoS Pathogens, Vol 13, Iss 12, p e1006725 (2017)
PLoS Pathogens, Public Library of Science, 2017, 13 (12), pp.e1006725. ⟨10.1371/journal.ppat.1006725⟩
Leptospirosis is a widespread zoonosis, potentially severe in humans, caused by spirochetal bacteria, Leptospira interrogans (L. interrogans). Host defense mechanisms involved in leptospirosis are poorly understood. Recognition of lipopolysaccharide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::58b6c92569cc57afab3eba8d35da0926
https://escholarship.org/uc/item/9k5615wn
https://escholarship.org/uc/item/9k5615wn
Publikováno v:
Cell Host and Microbe
Cell Host and Microbe, 2014, 15 (6), pp.792--798. ⟨10.1016/j.chom.2014.05.003⟩
Cell Host and Microbe, Elsevier, 2014, 15 (6), pp.792--798. ⟨10.1016/j.chom.2014.05.003⟩
Cell Host and Microbe, 2014, 15 (6), pp.792--798. ⟨10.1016/j.chom.2014.05.003⟩
Cell Host and Microbe, Elsevier, 2014, 15 (6), pp.792--798. ⟨10.1016/j.chom.2014.05.003⟩
Comment in : Nod-like receptors have a grip on stem cells. [Cell Host Microbe. 2014]; International audience; The intestinal crypt is a site of potential interactions between microbiota products, stem cells, and other cell types found in this niche,
Publikováno v:
médecine/sciences
médecine/sciences, 2013, 29 (6-7), pp.586-589. ⟨10.1051/medsci/2013296011⟩
médecine/sciences, EDP Sciences, 2013, 29 (6-7), pp.586-589. ⟨10.1051/medsci/2013296011⟩
médecine/sciences, 2013, 29 (6-7), pp.586-589. ⟨10.1051/medsci/2013296011⟩
médecine/sciences, EDP Sciences, 2013, 29 (6-7), pp.586-589. ⟨10.1051/medsci/2013296011⟩
table). Ceux-ci creeront a terme une flore intestinale commu-nement appelee microbiote. Compose de milliers d’especes bacteriennes, le microbiote intestinal peut etre consi-dere comme un organe a part entiere, qui consomme, stocke et redistribue l
Autor:
Ramnik J. Xavier, Jessica Quintin, Daniela C. Ifrim, Dirk J. de Jong, Joke van Loenhout, Leo A. B. Joosten, Sadia Saeed, Jos W. M. van der Meer, Reinout van Crevel, Cor Jacobs, Johanneke Kleinnijenhuis, Hendrik G. Stunnenberg, Frank Preijers, Mihai G. Netea
Publikováno v:
Proceedings of the National Academy of Sciences USA, 109, 17537-17542
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (43), pp.17537-17542. ⟨10.1073/pnas.1202870109⟩
Proceedings of the National Academy of Sciences USA, 109, 43, pp. 17537-17542
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (43), pp.17537-17542. ⟨10.1073/pnas.1202870109⟩
Proceedings of the National Academy of Sciences USA, 109, 43, pp. 17537-17542
Item does not contain fulltext Adaptive features of innate immunity, recently described as "trained immunity," have been documented in plants, invertebrate animals, and mice, but not yet in humans. Here we show that bacille Calmette-Guerin (BCG) vacc
Autor:
Anne Duperrier, Cécile Courivaud, Didier Ducloux, Philippe Saas, Christophe Ferrand, Pierre Tiberghien, Marina Deschamps, Jean-Marc Chalopin
Publikováno v:
Transplantation
Transplantation, Lippincott, Williams & Wilkins, 2006, 81 (8), pp.1212-5. ⟨10.1097/01.tp.0000202846.17619.a4⟩
Transplantation, Lippincott, Williams & Wilkins, 2006, 81 (8), pp.1212-5. ⟨10.1097/01.tp.0000202846.17619.a4⟩
International audience; Stable renal transplant recipients (RTR) display high rates of atherosclerotic events (AE). Innate immunity and especially vascular inflammation play a role in the pathogenesis of atherosclerosis. It is illustrated both by an
Autor:
Jean-Pierre Hugot, Philippe Mathurin, Sylvie Hudault, Sébastien Dharancy, Laurent Dubuquoy, Mathias Chamaillard, Filomena Conti, Pierre Desreumaux, Irene Garcia, Alexandre Louvet, Dominique Berrebi, Emilie Gantier, Philippe J. Sansonetti, Dana J. Philpott, Fabrice Chareyre, Mathilde Body-Malapel, Gilles Pagès, Marco Giovannini, Stephen E. Girardin
Publikováno v:
Laboratory Investigation, Vol. 88, No 3 (2008) pp. 318-327
Laboratory Investigation
Laboratory Investigation, 2008, 88 (3), pp.318-27. ⟨10.1038/labinvest.3700716⟩
Laboratory Investigation, Nature Publishing Group, 2008, 88 (3), pp.318-27. 〈10.1038/labinvest.3700716〉
Laboratory Investigation, Nature Publishing Group, 2008, 88 (3), pp.318-27. ⟨10.1038/labinvest.3700716⟩
Laboratory Investigation
Laboratory Investigation, 2008, 88 (3), pp.318-27. ⟨10.1038/labinvest.3700716⟩
Laboratory Investigation, Nature Publishing Group, 2008, 88 (3), pp.318-27. 〈10.1038/labinvest.3700716〉
Laboratory Investigation, Nature Publishing Group, 2008, 88 (3), pp.318-27. ⟨10.1038/labinvest.3700716⟩
The recent discovery of bacterial receptors such as NOD2 that contribute to crosstalk between innate and adaptive immune systems in the digestive tract constitutes an important challenge in our understanding of liver injury mechanisms. The present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3326dcca9698b46c147b13fae1059d9
https://archive-ouverte.unige.ch/unige:11162
https://archive-ouverte.unige.ch/unige:11162