Natural polymeric 3-alkylpyridinium salt affects vertebrate skeletal muscle contractility by preferentially blocking neuromuscular transmission

Autor: Monika C. Žužek, Robert Frangež, Marjana Grandič, Evelyne Benoit

Publikováno v: Toxicology Letters
Toxicology Letters, Elsevier, 2017, 281, pp.95-101. ⟨10.1016/j.toxlet.2017.09.007⟩
Toxicology Letters, 2017, 281, pp.95-101. ⟨10.1016/j.toxlet.2017.09.007⟩

International audience; The effects of natural polymeric alkylpyridinium salt (nPoly-3-APS), a potent acetylcholinesterase inhibitor isolated from the marine sponge Reniera sarai, were studied on isolated mouse phrenic nerve-hemidiaphragm muscle prep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68dad56862b906e86000f569e068f606
https://pubmed.ncbi.nlm.nih.gov/28939337

Inhibition of β-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis

Autor: Henriques, Alexandre, Huebecker, Mylene, Blasco, Hélène, Keime, Céline, Andres, Christian, Corcia, Philippe, Priestman, David, Platt, Frances, Spedding, Michael, Loeffler, Jean-Philippe

Publikováno v: Scientific Reports
Scientific Reports, 2017, 7 (1), pp.5235. ⟨10.1038/s41598-017-05313-0⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.5235. ⟨10.1038/s41598-017-05313-0⟩

International audience; Recent metabolomic reports connect dysregulation of glycosphingolipids, particularly ceramide and glucosylceramide, to neurodegeneration and to motor unit dismantling in amyotrophic lateral sclerosis at late disease stage. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::203e5fa75b09fea7e92e9f3f5ea4e75b
https://www.hal.inserm.fr/inserm-03375219

The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors

Autor: Morgane Reynaud, Evelyne Benoit, Denis Servent, Aurélie Couesnon, Rómulo Aráoz, Bogdan I. Iorga, Jordi Molgó

Publikováno v: Toxins
Toxins, MDPI, 2016, 8 (9), pp.249. ⟨10.3390/toxins8090249⟩
Toxins, Vol 8, Iss 9, p 249 (2016)
Toxins, 2016, 8 (9), pp.249. ⟨10.3390/toxins8090249⟩
Toxins; Volume 8; Issue 9; Pages: 249

International audience; The cyclic imine toxin 20-methyl spirolide G (20-meSPX-G), produced by the toxigenic dinoflagellate Alexandrium ostenfeldii/Alexandrium peruvianum, has been previously reported to contaminate shellfish in various European coas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ac30f4e7dc6f7152b374772060feac
http://europepmc.org/articles/PMC5037475

CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development

Autor: Véronique Bernard, Stéphanie Backer, Evelyne Bloch-Gallego, Nathalie Chaverot, Ariane Dimitrov, Jordi Molgó, Franck Perez, Nicolas Offner, Aurélie Couesnon

Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), 2013, 140 (7), pp.1583-93. ⟨10.1242/dev.087106⟩
Development (Cambridge, England), Company of Biologists, 2013, 140 (7), pp.1583-93. ⟨10.1242/dev.087106⟩
Development (Cambridge, England), Company of Biologists, 2013, 140 (7), pp.1583-1593. ⟨10.1242/dev.087106⟩
Development (Cambridge, England), Company of Biologists, 2013, 140 (7), pp.1583-93. 〈10.1242/dev.087106〉

International audience; CLIPR-59 is a new member of the cytoplasmic linker proteins (CLIP) family mainly localized to the trans-Golgi network. We show here that Clipr-59 expression in mice is restricted to specific pools of neurons, in particular mot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212d94f98f508f5b0f16aee12cf16ffa
https://hal.science/hal-00850320

Wnt4 participates in the formation of vertebrate neuromuscular junction

Autor: Claire Legay, Jérôme Rouvière, Laure Strochlic, Francine Bourgeois, Laurent Schaeffer, Séverine M. Sigoillot, Amanda Swain, Valérie Castellani, Perrine Delers, Julien Falk, Evelyne Goillot

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (1), pp.e29976. ⟨10.1371/journal.pone.0029976⟩
PLoS ONE, Vol 7, Iss 1, p e29976 (2012)
PLoS ONE, 2012, 7 (1), pp.e29976. ⟨10.1371/journal.pone.0029976⟩
PLoS ONE, Public Library of Science, 2012, 7 (1), pp.e29976. 〈10.1371/journal.pone.0029976〉
Plos One 1 (7), . (2012)

International audience; Neuromuscular junction (NMJ) formation requires the highly coordinated communication of several reciprocal signaling processes between motoneurons and their muscle targets. Identification of the early, spatially restricted cue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e034527f3d29164b5b1654b4de692b
https://hal.archives-ouvertes.fr/hal-00720087/file/2012_Strochlic_journal-pone_1.pdf