Comment on 'Tumor-initiating cells establish an IL-33–TGF-β niche signaling loop to promote cancer progression'

Autor: Julien Stackowicz, Aurélie Mougel, Pierre Bruhns, Jinmiao Chen, Eva Conde, William P. M. Worrall, Rebecca Gentek, Jasper B. J. Kamphuis, Nicolas Gaudenzio, Laurent L. Reber, Laurent Guilleminault, Emilie Mauré

Publikováno v: Science
Science, American Association for the Advancement of Science, 2021, 372 (6538), pp.eabf2022. ⟨10.1126/science.abf2022⟩
Science, 2021, 372 (6538), pp.eabf2022. ⟨10.1126/science.abf2022⟩

Taniguchi et al . (Research Articles, 17 July 2020, p. 269) claim that the cytokine interleukin-33 induces accumulation of tumor-associated macrophages expressing the immunoglobulin E receptor FcεRI. Although these findings hold great therapeutic pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4630eca1effa53326d86449693048bcb
https://doi.org/10.1126/science.abf2022

Vision 2030 pour une approche optimale de la recherche et des soins contre le cancer en Europe : Une mission ou un réseau de réseaux ?

Autor: Thierry Philip, Philip Poortmans, Geneviève Almouzni

Publikováno v: Tumori
Tumori, Casa Editrice Ambrosiana, 2019, 105 (3), pp.265-270. ⟨10.1177/0300891618783655⟩

International audience; Introduction: A mission-oriented approach to cancer care in Europe was proposed by Julio Celis and Dainius Pavalkis in 2017. The major proposed objective is to achieve long-term survival of 3 out of 4 cancer patients by 2030.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1e6b7337e4c9ba74abf5c4bdaa9440
https://doi.org/10.1177/0300891618783655

Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides

Autor: Wassim Moslah, Soumaya Souid, Jed Jebali, Dorra Aissaoui, Houcemeddine Othman, Mohamed Elayeb, Saoussen Mlayah-Bellalouna, José Luis, Zaineb Abdelkafi-Koubaa, Khadija Essafi-Benkhadir, Naziha Marrakchi, Najet Srairi-Abid

Publikováno v: International Journal of Biological Macromolecules
International Journal of Biological Macromolecules, 2018, 111, pp.1146-1155. ⟨10.1016/j.ijbiomac.2018.01.144⟩
International Journal of Biological Macromolecules, Elsevier, 2018, 111, pp.1146-1155. ⟨10.1016/j.ijbiomac.2018.01.144⟩

International audience; Voltage-gated potassium (Kv) channels are known to play a pivotal role in the progression of various cancer types and considered as new targets for designing anti-cancer therapy. However, the fact that many Kv channels are exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9397ccddf29007935bd17cae2ee4bb23
https://hal-amu.archives-ouvertes.fr/hal-01765752

Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis

Autor: Samuel T Workenhe, Akiko Yanagiya, Huy-Dung Hoang, Soroush Tahmasebi, Dana Pearl, Adrian Pelin, John C. Bell, Chadi Zakaria, Karen L. Mossman, Tyson E. Graber, Jaclyn Hearnden, Polen Sean, Tommy Alain, Jian-Jun Jia, Margaret Watson, Louis-Phillipe Leroux, Seyed Mehdi Jafarnejad, Jean-Simon Diallo, Nahum Sonenberg, Maritza Jaramillo, Nathaniel Robichaud, Vinh Tai Truong, Fabrice Le Boeuf

Publikováno v: Zakaria, C, Sean, P, Hoang, H-D, Leroux, L-P, Watson, M, Workenhe, S T, Hearnden, J, Pearl, D, Truong, V T, Robichaud, N, Yanagiya, A, Tahmasebi, S, Jafarnejad, S M, Jia, J-J, Pelin, A, Diallo, J-S, Le Boeuf, F, Bell, J C, Mossman, K L, Graber, T E, Jaramillo, M, Sonenberg, N & Alain, T 2018, ' Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis ', PLoS Pathogens, vol. 14, no. 8, e1007264 . https://doi.org/10.1371/journal.ppat.1007264
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2018, 14 (8), pp.e1007264. ⟨10.1371/journal.ppat.1007264⟩
PLoS Pathogens, Vol 14, Iss 8, p e1007264 (2018)

International audience; Herpes Simplex Virus 1 (HSV1) is amongst the most clinically advanced oncolytic virus platforms. However, efficient and sustained viral replication within tumours is limiting. Rapamycin can stimulate HSV1 replication in cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c92dee5a0216e1929b4920ce8f0aa3
https://pubmed.ncbi.nlm.nih.gov/30138450

Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation

Autor: Emilie Andrio, Emmanuel Lemichez, Jacqueline Cherfils, Poul H. Sorensen, Anne Doye, Daniel Hamaoui, Mads Daugaard, Raymond Ruimy, Frédéric Bost, Amel Mettouchi, Romain Lotte

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.44779. ⟨10.1038/srep44779⟩
Scientific Reports, 2017, 7 (1), pp.44779. ⟨10.1038/srep44779⟩

The E3 ubiquitin ligase HACE1 is a potent tumor suppressor that controls cell proliferation and ubiquitylates the small GTPase Rac1 to target it to proteasomal degradation. Whether and how the activity of HACE1 is regulated by the N-terminal ankyrin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369d0aeadf452cafe8e400b065e715d7
https://doi.org/10.1038/srep44779