Zobrazeno 1 - 10
of 19
pro vyhledávání: '"MESH: N-Acetylneuraminic Acid"'
Autor:
Alejandra Tortorici, M, Walls, Alexandra C, Lang, Yifei, Wang, Chunyan, Li, Zeshi, Koerhuis, Danielle, Boons, Geert-Jan, Bosch, Berend-Jan, Rey, Félix A, de Groot, Raoul J, Veesler, David, LS Virologie, dI&I I&I-1, Sub Chemical Biology and Drug Discovery, Afd Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
Publikováno v:
Nature structural & molecular biology
Nature Structural and Molecular Biology, 26(6), 481. Nature Publishing Group
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2019, 26 (6), pp.481-489. ⟨10.1038/s41594-019-0233-y⟩
Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (6), pp.481-489. ⟨10.1038/s41594-019-0233-y⟩
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology, 26(6), 481. Nature Publishing Group
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2019, 26 (6), pp.481-489. ⟨10.1038/s41594-019-0233-y⟩
Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (6), pp.481-489. ⟨10.1038/s41594-019-0233-y⟩
Nature Structural & Molecular Biology
International audience; Coronaviruses cause respiratory tract infections in humans and outbreaks of deadly pneumonia worldwide. Infections are initiated by the transmembrane spike (S) glycoprotein, which binds to host receptors and fuses the viral an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b98687f21198f50e0d888b82868e58b
https://pubmed.ncbi.nlm.nih.gov/31160783
https://pubmed.ncbi.nlm.nih.gov/31160783
Publikováno v:
Trends Microbiol
Trends Microbiol, 2011, 19 (7), pp.341-8. ⟨10.1016/j.tim.2011.04.003⟩
Trends Microbiol, 2011, 19 (7), pp.341-8. 〈10.1016/j.tim.2011.04.003〉
Trends Microbiol, 2011, 19 (7), pp.341-8. ⟨10.1016/j.tim.2011.04.003⟩
Trends Microbiol, 2011, 19 (7), pp.341-8. 〈10.1016/j.tim.2011.04.003〉
It is interesting to speculate that the evolutionary drive of microbes to develop pathogenic characteristics was to access the nutrient resources that animals provided. Environments in animals that pathogens colonize have also driven the evolution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c7a4b9208d1d3edb64eb9240d1d7f8
https://doi.org/10.1016/j.tim.2011.04.003
https://doi.org/10.1016/j.tim.2011.04.003
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2009, 15 (21), pp.5195-9. ⟨10.1002/chem.200900093⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2009, 15 (21), pp.5195-9. ⟨10.1002/chem.200900093⟩
International audience; A regio- and stereocontrolled solution for a selective modification at the C-2 or C-4 position of N-acetylneuraminic acid involves the use of allylic substitution catalyzed by palladium. As illustrated in the scheme, regiosele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630a7576bcf95a1dc44f1712bd34abac
https://doi.org/10.1002/chem.200900093
https://doi.org/10.1002/chem.200900093
Autor:
Alberto C.C. Frasch, Michael H. Charlton, Paul N. Mortenson, Richard A. Bryce, Horacio Botti, Mark L. Brewer, Pedro M. Alzari, Alejandro Buschiazzo, João Neres, Kenneth T. Douglas, Laura Ratier, Philip Neil Edwards
Publikováno v:
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2009, 19 (3), pp.589-596. ⟨10.1016/j.bmcl.2008.12.065⟩
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (3), pp.589-596. ⟨10.1016/j.bmcl.2008.12.065⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2009, 19 (3), pp.589-596. ⟨10.1016/j.bmcl.2008.12.065⟩
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (3), pp.589-596. ⟨10.1016/j.bmcl.2008.12.065⟩
International audience; trans-Sialidase from Trypanosoma cruzi (TcTS) has emerged as a potential drug target for treatment of Chagas disease. Here, we report the results of virtual screening for the discovery of novel TcTS inhibitors, which targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d3df2ee80c2f17123994ec9e40de52
https://doi.org/10.1016/j.bmcl.2008.12.065
https://doi.org/10.1016/j.bmcl.2008.12.065
Autor:
Nancy J. Rusch, Parastoo Azadi, Maritza V. Quintero, Fusun Kilic, Luc Maroteaux, Krajang Talabnin, Preeti Singh, Charles P. Mercado, Yicong Li, Balagurunathan Kuberan, Alicia K. Byrd, Mayumi Ishihara
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2013, 3, pp.2795. ⟨10.1038/srep02795⟩
Scientific Reports, 2013, 3, pp.2795. ⟨10.1038/srep02795⟩
Scientific Reports, Nature Publishing Group, 2013, 3, pp.2795. ⟨10.1038/srep02795⟩
Scientific Reports, 2013, 3, pp.2795. ⟨10.1038/srep02795⟩
International audience; Serotonin (5-HT) is a multifunctional signaling molecule that plays different roles in a concentration-dependent manner. We demonstrated that elevated levels of plasma 5-HT accelerate platelet aggregation resulting in a hyperc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3682293f711cec6a0983b2e5de6cd90
https://www.hal.inserm.fr/inserm-00996761/file/srep02795.pdf
https://www.hal.inserm.fr/inserm-00996761/file/srep02795.pdf
Autor:
Gérard J. Arlaud, Christine Moriscot, Andrea Doni, Guy Schoehn, Chantal Dumestre-Pérard, Nicole M. Thielens, Monique Lacroix, Evelyne Gout, Julien Pérard, Alberto Mantovani
Publikováno v:
Journal of Immunology
Journal of Immunology, 2011, 186 (10), pp.5815-22. ⟨10.4049/jimmunol.1100180⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2011, 186 (10), pp.5815-22. ⟨10.4049/jimmunol.1100180⟩
Journal of Immunology, 2011, 186 (10), pp.5815-22. ⟨10.4049/jimmunol.1100180⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2011, 186 (10), pp.5815-22. ⟨10.4049/jimmunol.1100180⟩
Ficolins and pentraxins are soluble oligomeric pattern-recognition molecules that sense danger signals from pathogens and altered self-cells and might act synergistically in innate immune defense and maintenance of immune tolerance. The interaction o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d8a233d58131effeabdf3ab1ae71ac
https://hal.science/hal-00995657
https://hal.science/hal-00995657
Autor:
Anne Harduin-Lepers, Anne Imberty, Christelle Breton, Charlotte Jeanneau, Philippe Delannoy, Magali Audry
Publikováno v:
Glycobiology
Glycobiology, Oxford University Press (OUP), 2011, 21 (6), pp.716-726. ⟨10.1093/glycob/cwq189⟩
Glycobiology, Oxford University Press (OUP), 2011, 21 (6), pp.716-26
Glycobiology, Oxford University Press (OUP), 2011, pp.716-726
Glycobiology, 2011, 21 (6), pp.716-26
Glycobiology, Oxford University Press (OUP), 2011, 21 (6), pp.716-726. ⟨10.1093/glycob/cwq189⟩
Glycobiology, Oxford University Press (OUP), 2011, 21 (6), pp.716-26
Glycobiology, Oxford University Press (OUP), 2011, pp.716-726
Glycobiology, 2011, 21 (6), pp.716-26
International audience; Sialyltransferases (STs) represent an important group of enzymes that transfer N-acetylneuraminic acid (Neu5Ac) from cytidine monophosphate-Neu5Ac to various acceptor substrates. In higher animals, sialylated oligosaccharide s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbcf8662e479c06ceabb45eda9b48e2
https://hal.archives-ouvertes.fr/hal-02350674
https://hal.archives-ouvertes.fr/hal-02350674
Autor:
Pierre Youinou, Yves Renaudineau, Rizgar A. Mageed, Divi Cornec, Sophie Hillion, Jean-François Séité
Publikováno v:
Blood
Blood, American Society of Hematology, 2010, 116 (10), pp.1698-704. ⟨10.1182/blood-2009-12-261461⟩
Blood, American Society of Hematology, 2010, 116 (10), pp.1698-704. ⟨10.1182/blood-2009-12-261461⟩
Among various mechanisms for interactions with B cells, intravenous immunoglobulin (IVIg) may operate through the insertion of its Fc part into the Fc-γ receptor, or the binding of its sialic acid (SA)–bearing glycans to the negatively regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48e5e21038672a62b0398d76010bcec
https://hal.archives-ouvertes.fr/hal-01150519/file/JFSDC.pdf
https://hal.archives-ouvertes.fr/hal-01150519/file/JFSDC.pdf
Autor:
Julie Beneteau, Didier Dupont, Denis Renard, Sylvie Dinant, Laurence Lavenant, Françoise Vilaine, Yvan Rahbé, Elise Douville, Laurent Marche
Publikováno v:
Plant Physiology
Plant Physiology, American Society of Plant Biologists, 2010, 153 (3), pp.1345-61. ⟨10.1104/pp.110.153882⟩
Plant Physiology, 2010, 153 (3), pp.1345-61. ⟨10.1104/pp.110.153882⟩
Plant Physiology, American Society of Plant Biologists, 2010, 153 (3), pp.1345-61. ⟨10.1104/pp.110.153882⟩
Plant Physiology, 2010, 153 (3), pp.1345-61. ⟨10.1104/pp.110.153882⟩
L'article original est publié par The American Society of Plant Biologists; International audience; Phloem Protein2 (PP2) is a component of the phloem protein bodies found in sieve elements. We describe here the lectin properties of the Arabidopsis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8af9b7ef59fa399a66b675a6083835
https://hal.inria.fr/hal-00850393
https://hal.inria.fr/hal-00850393
Autor:
David Bonnaffé, Philippe Delannoy, Francoise Vinet, Aurélie Cazet, Isabelle Texier, Laurent Guyon, Aude Bernardin
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2010, 21 (4), pp.583-8. ⟨10.1021/bc900564w⟩
Bioconjugate Chemistry, 2010, 21 (4), pp.583-8. ⟨10.1021/bc900564w⟩
Bioconjugate Chemistry, American Chemical Society, 2010, 21 (4), pp.583-8. ⟨10.1021/bc900564w⟩
Bioconjugate Chemistry, 2010, 21 (4), pp.583-8. ⟨10.1021/bc900564w⟩
International audience; Quantum dots (QD) are inorganic nanocrystals with outstanding optical properties, specially suited for biological imaging applications. Their attachment to biomolecules in mild aqueous conditions for the design of bioconjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00af23df6ebf9f19444644647b1ff112
https://pubmed.ncbi.nlm.nih.gov/20222737
https://pubmed.ncbi.nlm.nih.gov/20222737