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Initial Symbiont Contact Orchestrates Host-Organ-wide Transcriptional Changes that Prime Tissue Colonization

Autor: Eva E. R. Philipp, Robert Häsler, Philip Rosenstiel, Marie-Christine Carpentier, Edward G. Ruby, Margaret J. McFall-Ngai, Lars Kraemer, Natacha Kremer, Bethany A. Rader, Caitlin A. Brennan, René Augustin, Elizabeth A. C. Heath-Heckman, Julia A. Schwartzman, Melissa A. Altura, Suzanne M. Peyer

Publikováno v: Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2013, 14 (2), pp.183-94. ⟨10.1016/j.chom.2013.07.006⟩
Cell Host and Microbe, 2013, 14 (2), pp.183-94. ⟨10.1016/j.chom.2013.07.006⟩

International audience; Upon transit to colonization sites, bacteria often experience critical priming that prepares them for subsequent, specific interactions with the host; however, the underlying mechanisms are poorly described. During initiation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f53850b51dde6514e51ac066270d6a

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High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine

Autor: Thierry Pedron, Chek Kun Tan, Kalina Duszka, Robert Ducroc, Philippe J. Sansonetti, Céline Mulet, Rémy Burcelin, Azadeh Saffarian, Béatrice Regnault, Walter Wahli, Jean-Baptiste Cavin, Julie Tomas

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (40), pp.E5934-E5943. ⟨10.1073/pnas.1612559113⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (40), ⟨10.1073/pnas.1612559113⟩
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (40), ⟨10.1073/pnas.1612559113⟩
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (40), pp.E5934-E5943. ⟨10.1073/pnas.1612559113⟩
Proceedings of the National Academy of Sciences of the United States of America 40 (113), E5934-E5943. (2016)

International audience; Diet is among the most important factors contributing to intestinal homeostasis, and basic functions performed by the small intestine need to be tightly preserved to maintain health. Little is known about the direct impact of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d715e572206c92d4584b1dc57bc59c5
https://hal-pasteur.archives-ouvertes.fr/pasteur-02554241

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Transcriptional response of mucoid Pseudomonas aeruginosa to human respiratory mucus

Autor: Reuben Ramphal, Damien Roux, Hugues Aschard, Vincent Cattoir, Stephen Lory, David Skurnik, Jeevan Jyot, Giri Narasimhan

Publikováno v: mBio
mBio, American Society for Microbiology, 2012, 3 (6), pp.e00410-12. ⟨10.1128/mBio.00410-12⟩
mBio, Vol 3, Iss 6 (2012)

Adaptation of bacterial pathogens to a host can lead to the selection and accumulation of specific mutations in their genomes with profound effects on the overall physiology and virulence of the organisms. The opportunistic pathogen Pseudomonas aerug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3994122887f8500f04b2a0c03e4364b
https://pubmed.ncbi.nlm.nih.gov/23143799

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Toward the modeling of mucus draining from the human lung: role of the geometry of the airway tree

Autor: Dominique Pelca, Benjamin Mauroy, Jacques Merckx, Patrice Flaud, Christian Fausser

Publikováno v: Physical Biology
Physical Biology, Institute of Physics: Hybrid Open Access, 2011, 8 (5), pp.056006. ⟨10.1088/1478-3975/8/5/056006⟩

International audience; Mucociliary clearance and cough are the two main natural mucus draining methods in the bronchial tree. If they are affected by a pathology, they can become insufficient or even ineffective, then therapeutic draining of mucus p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6301aadb409743ee3531cdb127257d48
https://hal.archives-ouvertes.fr/hal-00916472

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Critical role of cytosolic phospholipase A2 in bronchial mucus hypersecretion in CFTR-deficient mice

Autor: Lhousseine Touqui, Aarbiou J, Bob J. Scholte, Yongzheng Wu, Y. Kita, Pierre-Régis Burgel, Borot F, Michel Chignard, Ollero M, Clémence Martin, Fariel Dif, Ignacio Garcia-Verdugo, D. Israel-Biet, Dimitri Leduc

Publikováno v: European Respiratory Journal
European Respiratory Journal, 2010, 36 (5), pp.1120-1130. ⟨10.1183/09031936.00183409⟩
European Respiratory Journal, 36(5), 1120-1130. European Respiratory Society
European Respiratory Journal, European Respiratory Society, 2010, 36 (5), pp.1120-1130. ⟨10.1183/09031936.00183409⟩

Cystic fibrosis (CF) is due to mutations in the CF transmembrane conductance regulator gene CFTR. CF is characterised by mucus dehydration, chronic bacterial infection and inflammation, and increased levels of cytosolic phospholipase A2 alpha (cPLA2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ca3cac07312cba69eba555c3cbf17d
https://hal-pasteur.archives-ouvertes.fr/pasteur-02863044

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Conservation, development, and function of a cement gland-like structure in the fish Astyanax mexicanus

Autor: Karen Pottin, Sylvie Rétaux, Carole Hyacinthe

The larvae of the fish Astyanax mexicanus transiently develop a flat and adhesive structure on the top of their heads that we have called “the casquette” (cas, meaning “hat”). We hypothesized that the cas may be a teleostean homolog of the we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b55362f757ae213c28a319e68ad0654
https://hal.archives-ouvertes.fr/hal-00586178

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Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice

Autor: Brattström, A., Schapowal, A., Maillet, I., Schnyder, B., Ryffel, Bernhard, Moser, R.

Publikováno v: Phytotherapy Research
Phytotherapy Research, Wiley, 2010, 24 (5), pp.680-5. ⟨10.1002/ptr.2972⟩

International audience; BACKGROUND: The herbal Petasites hybridus (butterbur) extract (Ze 339, PET) is known to have leukotriene inhibiting properties, and therefore might inhibit allergic diseases. METHODS: The effect of PET was investigated in oval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::765bf9dbbf589db99e5bbdad5191004f
https://pubmed.ncbi.nlm.nih.gov/19827027

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The plant extract Isatis tinctoria L. extract (ITE) inhibits allergen-induced airway inflammation and hyperreactivity in mice

Autor: Isabelle Maillet, René Moser, A. Brattström, A. Schapowal, Bernhard Ryffel, M.A. Kamal

Publikováno v: Phytomedicine
Phytomedicine, Elsevier, 2010, 17 (8-9), pp.551-6. ⟨10.1016/j.phymed.2009.11.003⟩

International audience; BACKGROUND: The herbal Isatis tinctoria extract (ITE) inhibits the inducible isoform of cyclooxygenase (COX-2) as well as lipoxygenase (5-LOX) and therefore possesses anti-inflammatory properties. The extract might also be use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ace29ad194696d838df17012339b8a
https://pubmed.ncbi.nlm.nih.gov/20092989

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Is respiratory mucus hypersecretion really an innocent disorder? A 22-year mortality survey of 1,061 working men

Autor: Annesi, I., Kauffmann, F.

Publikováno v: Am Rev Respir Dis
Am Rev Respir Dis, 1986, 134 (4), pp.688-93

International audience; The relation of chronic air-flow limitation and respiratory mucus hypersecretion to all causes of mortality was studied in a population of 1,061 men working in the Paris area, surveyed initially in 1960/1961, and followed for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::647f771b397d0bb75ac1e626868d1d51
https://hal.sorbonne-universite.fr/hal-00596567

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