Zobrazeno 1 - 10 of 29 pro vyhledávání: '"MESH: Metformin"'
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Type-2 diabetes patients at high risk for cardiovascular events: time to challenge the ‘metformin-always first’ paradigm
Autor: Naveed Sattar, Victor Aboyans
Publikováno v: European Journal of Preventive Cardiology
European Journal of Preventive Cardiology, Sage Publications, 2021, 28 (1), pp.66-68. ⟨10.1093/eurjpc/zwaa157⟩
International audience
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8485761fdb0dbef124981f1b51ddcb1f
https://doi.org/10.1093/eurjpc/zwaa157
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2
Near-infrared light activatable hydrogels for metformin delivery
Autor: Alexandre Barras, Valérie Plaisance, Nathalie Hennuyer, Amar Abderrahmani, Quentin Pagneux, Nadia Skandrani, Rabah Boukherroub, Anna Voronova, Sabine Szunerits, Valérie Pawlowski, Bart Staels, Musen Li, Lea Rosselle, Li Chengnan
Publikováno v: Nanoscale
Nanoscale, Royal Society of Chemistry, 2019, 11 (34), pp.15810-15820. ⟨10.1039/c9nr02707f⟩
Nanoscale, 2019, 11 (34), pp.15810-15820. ⟨10.1039/c9nr02707f⟩
International audience; Drug loaded hydrogels have proven to be versatile controlled-release systems. We report here on heat active hydrogel formation by mixing graphene oxide (GO) or carboxyl enriched reduced graphene oxide (rGO-COOH) with metformin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07257f0932388258ffbf2569e1d070c3
https://hal.archives-ouvertes.fr/hal-03090103
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4
Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation
Autor: Ahmed Alshawi, Loranne Agius, Marc Foretz, Benoit Viollet, Silvia Marin, Natasha S. Adam-Primus, Shruti S. Chachra, Ziad H. Al-Oanzi, Tabassum Moonira, Marta Cascante, Catherine Arden, Brian E. Ford
Publikováno v: The Journal of Biological Chemistry
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (10), pp.3330-3346. ⟨10.1074/jbc.ra120.012533⟩
International audience; The chronic effects of metformin on liver gluconeogenesisinvolve repression of theG6pcgene, which is regulated by thecarbohydrate-response element–binding protein throughraised cellular intermediates of glucose metabolism. I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f735b9110a996135298766fd5778907
https://pubmed.ncbi.nlm.nih.gov/31974165
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5
Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism
Autor: Jorge Joven, Sara Verdura, Salvador Fernández-Arroyo, Elisa Blanco-González, Javier A. Menendez, Maria Montes-Bayón, Jan Stursa, R Á-F García, Elisabet Cuyàs, Benoit Viollet, Lukas Werner, Jiri Neuzil
Publikováno v: Oncogene
Oncogene, Nature Publishing Group, 2018, 37 (7), pp.963-970. ⟨10.1038/onc.2017.367⟩
Oncogene, 2018, 37 (7), pp.963-970. ⟨10.1038/onc.2017.367⟩
International audience; The anti-diabetic biguanide metformin may exert health-promoting effects via metabolic regulation of the epigenome. Here we show that metformin promotes global DNA methylation in non-cancerous, cancer-prone and metastatic canc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cacc1e433298e67858d2257a3255a11
https://doi.org/10.1038/onc.2017.367
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6
Evaluation of vitamin B12 monitoring in patients on metformin in urban ambulatory care settings
Autor: Michael P. Conley, Kelsey B Sheehan, Jessica M Ryan, Debra J. Reid, Carla Bouwmeester, Stacy L Longo
Publikováno v: Pharmacy Practice
Pharmacy Practice, Vol 17, Iss 3, p 1499 (2019)
Pharmacy Practice (Granada), Volume: 17, Issue: 3, Article number: 1499, Published: 25 NOV 2019
Pharmacy Practice (Granada) v.17 n.3 2019
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Background: Previous studies linked metformin use to vitamin B12 deficiency and demonstrated that the prevalence of vitamin B12 monitoring remains low. Objective: This study aimed to assess the occurrence of monitoring vitamin B12 levels in a diverse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670886f04ab1363d6fb67469155571ed
https://pubmed.ncbi.nlm.nih.gov/31592289
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7
Metformin directly targets the H3K27me3 demethylase KDM6A/UTX
Autor: Salvador Fernández-Arroyo, Lukas Werner, Jorge Joven, Laura Llorach-Parés, Javier A. Menendez, Noemí Cabré, Benoit Viollet, Sara Verdura, Elisabet Cuyàs, Fedra Luciano-Mateo, Jan Stursa, Alfons Nonell-Canals, Jiri Neuzil, Begoña Martin-Castillo, Melchor Sanchez-Martinez
Publikováno v: Aging Cell
Aging Cell, Wiley Open Access, 2018, 17 (4), pp.e12772. ⟨10.1111/acel.12772⟩
Aging Cell, 2018, 17 (4), pp.e12772. ⟨10.1111/acel.12772⟩
Aging Cell, 2018, vol. 17, núm. 4, p. e12772
Articles publicats (IdIBGi)
Cuyàs, Elisabet Verdura, Sara Llorach Parés, Laura Fernández-Arroyo S Luciano-Mateo, Fedra Cabré, Noemí Stursa, Jan Werner, Lukas Martin-Castillo, Begoña Viollet, Benoit Neuzil, Jiri Joven, Jorge Nonell-Canals, Alfons Sanchez Martinez, Melchor Menéndez Menéndez, Javier Abel 2018 Metformin directly targets the H3K27me3 demethylase KDM6A/UTX Aging Cell 17 4 e12772
DUGiDocs – Universitat de Girona
instname
International audience; Metformin, the first drug chosen to be tested in a clinical trial aimed to target the biology of aging per se, has been clinically exploited for decades in the absence of a complete understanding of its therapeutic targets or
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c1fe2779fda1f5a2a4aeca8373c4f6
https://www.hal.inserm.fr/inserm-02349904
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8
Intoxication à la metformine en réanimation : étude clinique, pronostique et pharmacocinétique
Autor: Peron, Nicolas
Publikováno v: Médecine humaine et pathologie. 2016
Rationale: metformin is the most prescribed anti-diabetic drug in the world. Its main complication called metformin associated lactic acidosis (MALA) is rare, but potentially fatal. The most common cause is the incidental metformin overdose, often tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9650db2c2f3887445e941ad42ed17234
https://dumas.ccsd.cnrs.fr/dumas-01630565
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9
Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE−/− Mice
Autor: Vincent Sarrazy, Sophie Giorgetti-Peraldi, Laurent Yvan-Charvet, Darryl C. De Vivo, Stoyan Ivanov, Edward B. Thorp, Manon Viaud, Emmanuel L. Gautier, Marit Westerterp, Rodolphe Guinamard
Publikováno v: Circulation Research
Circulation Research, 2016, 118 (7), pp.1062-1077. ⟨10.1161/CIRCRESAHA.115.307599⟩
Circulation Research, American Heart Association, 2016, 118 (7), pp.1062-1077. ⟨10.1161/circresaha.115.307599⟩
Circulation research, 118(7), 1062-1077. LIPPINCOTT WILLIAMS & WILKINS
Rationale: Inflamed atherosclerotic plaques can be visualized by noninvasive positron emission and computed tomographic imaging with 18 F-fluorodeoxyglucose, a glucose analog, but the underlying mechanisms are poorly understood. Objective: Here, we d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7526462fd8c30518bac6341c8c0df880
https://europepmc.org/articles/PMC4824305/
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10
Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway
Autor: Dominique Detaille, Elsa Briones, José M. López-Novoa, Xavier Leverve, Mohamad-Yehia El-Mir, Marta Prieto, Miguel Arévalo, Angel Puente, Ana I. Morales
Publikováno v: Kidney International
Kidney International, Nature Publishing Group, 2010, 77 (10), pp.861-9. ⟨10.1038/ki.2010.11⟩
International audience; The antidiabetic drug metformin can diminish apoptosis induced by oxidative stress in endothelial cells and prevent vascular dysfunction even in nondiabetic patients. Here we tested whether it has a beneficial effect in a rat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e057d34f363c20d073647181fe96dd25
https://doi.org/10.1038/ki.2010.11
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