Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR

Autor: Belot, Audrey, Gourbeyre, Ophélie, Palin, Anais, Rubio, Aude, Largounez, Amélie, Besson-Fournier, Celine, Latour, Chloé, Lorgouilloux, Megane, Gallitz, Inka, Montagner, Alexandra, Polizzi, Arnaud, Régnier, Marion, Smati, Sarra, Zhang, An-Sheng, Diaz-Munoz, Manuel, Steinbicker, Andrea, Guillou, Hervé, Roth, Marie-Paule, Coppin, Hélène, Meynard, Delphine

Publikováno v: Haematologica
Haematologica, Ferrata Storti Foundation, 2021, 106 (4), pp.1202-1206. ⟨10.3324/haematol.2019.237321⟩
Haematologica, 2021, 106 (4), pp.1202-1206. ⟨10.3324/haematol.2019.237321⟩

International audience; The liver hormone hepcidin controls the main inflows of iron into plasma by binding to and inducing the degradation or the occlusion of the iron export activity of ferroportin, the only known cellular exporter of iron. When he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0f448f7c0fa5f39da70266cfaf09528b
https://hal.inrae.fr/hal-02911817/document

Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice

Autor: Taiping Chen, John H. Richburg, Sharon Y.R. Dent, Raif S. Geha, Jean Louis Guénet, Caitlin J. Murphy, Carlos J. Perez, Janet Chou, Jean Jaubert, Tewfik Hamidi, Meichun Deng, Craig D. Platt, Qinghua Shi, Yue Lu, Héctor Gaitán-Peñas, Fernando Benavides, Kevin Lin, Jeesun Kim, Hui Lin Pan, Mark T. Bedford, Jianqiang Bao, Meng Hua Zhou, Huan Zhang, Yuying Huang, Raúl Estévez

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
JCI Insight
JCI Insight, American Society for Clinical Investigation, 2018, 3 (16), pp.e99767. ⟨10.1172/jci.insight.99767⟩
JCI Insight, 2018, 3 (16), pp.e99767. ⟨10.1172/jci.insight.99767⟩

International audience; Ion channel-controlled cell volume regulation is of fundamental significance to the physiological function of sperm. In addition to volume regulation, LRRC8A-dependent volume-regulated anion channel (VRAC) activity is involved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb59899d04360969f84ccb27e341fc46
http://hdl.handle.net/2445/172306

Neuralized regulates Crumbs endocytosis and epithelium morphogenesis via specific Stardust isoforms

Autor: Khalil Mazouni, François Schweisguth, Vanessa Roca, Gantas Perez-Mockus

Publikováno v: Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2017, 216 (5), pp.1405-1420. ⟨10.1083/jcb.201611196⟩
The Journal of Cell Biology
Journal of Cell Biology, 2017, 216 (5), pp.1405-1420. ⟨10.1083/jcb.201611196⟩

The E3 ubiquitin ligase Neuralized is shown to interact with a subset of the Stardust isoforms to regulate the endocytosis of the apical protein Crumbs and thereby promote epithelial remodeling during Drosophila development.
Crumbs (Crb) is a co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aaf0808c4d3ce591411bcb274d08019
https://hal-pasteur.archives-ouvertes.fr/pasteur-01799354

Protein–Protein Interaction: Bacterial Two-Hybrid

Autor: Daniel Ladant, Scot P. Ouellette, Gouzel Karimova, Emilie Gauliard, Marilyne Davi

Publikováno v: Methods in Molecular Biology ISBN: 9781493970315
Bacterial Protein Secretion Systems
Laure Journet; Eric Cascales. Bacterial Protein Secretion Systems, 1615, Humana Press; Springer Science, pp.159-176, 2017, Methods in Molecular Biology, 978-1-4939-7033-9. ⟨10.1007/978-1-4939-7033-9_13⟩

International audience; The bacterial two-hybrid (BACTH, for "Bacterial Adenylate Cyclase-Based Two-Hybrid") system is a simple and fast genetic approach to detecting and characterizing protein-protein interactions in vivo. This system is based on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26205e8fe843d6ae2d4fb2532a16152d
https://doi.org/10.1007/978-1-4939-7033-9_13

The CREB3-Herp signalling module limits the cytosolic calcium concentration increase and apoptosis induced by poliovirus

Autor: Bruno Blondel, François Téoulé, Isabelle Pelletier, Carmen Mirabelli, Pierre-Olivier Vidalain, Francis Delpeyroux, Cynthia Brisac, Frédéric Tangy

Publikováno v: Journal of General Virology
Journal of General Virology, Microbiology Society, 2016, 97 (9), pp.2194-2200. ⟨10.1099/jgv.0.000544⟩
Journal of General Virology, 2016, 97 (9), pp.2194-2200. ⟨10.1099/jgv.0.000544⟩

International audience; Poliovirus (PV)-induced apoptosis seems to play a major role in central nervous system (CNS) tissue injury, a crucial feature of the pathogenesis of poliomyelitis. We have previously shown that calcium (Ca2+) flux from the end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cf14904880fbef1be5bcc19c4ed036
https://hal.archives-ouvertes.fr/hal-02438329