Výsledky vyhledávání - "MESH: Matrix Metalloproteinase 2"

l-Arginine Decreases Inflammation and Modulates the Nuclear Factor-κB/Matrix Metalloproteinase Cascade in Mdx Muscle Fibers

Autor: Gérald Hugon, Jerome Gayraud, Karim Hnia, Stefan Matecki, Sabine De La Porte, Michèle Ramonatxo, Dominique Mornet

Publikováno v: American Journal of Pathology
American Journal of Pathology, 2008, 172 (6), pp.1509-19. ⟨10.2353/ajpath.2008.071009⟩
American Journal of Pathology, American Society for Investigative Pathology, 2008, 172 (6), pp.1509-19. ⟨10.2353/ajpath.2008.071009⟩

International audience; Duchenne muscular dystrophy (DMD) is a lethal, X-linked disorder associated with dystrophin deficiency that results in chronic inflammation, sarcolemma damage, and severe skeletal muscle degeneration. Recently, the use of L-ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de434d80bdd009cf201e037689a4ccfa
https://doi.org/10.2353/ajpath.2008.071009

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Protease-activated receptor 1 knockout reduces experimentally induced liver fibrosis

Autor: Anne Rullier, Nathalie Dugot-Senant, Jean Rosenbaum, Jennifer Gillibert-Duplantier, Gérard Déléris, Cyril Petibois, Pierre Costet, Gaelle Cubel, Valérie Haurie, Paulette Bioulac-Sage, Danièle Taras

Publikováno v: AJP-Gastrointestinal and Liver Physiology
AJP-Gastrointestinal and Liver Physiology, 2008, 294 (1), pp.G226-35. ⟨10.1152/ajpgi.00444.2007⟩

Thrombin inhibition protects against liver fibrosis. However, it is not known whether the thrombin profibrogenic effect is due to effects on blood coagulation or to signaling via protease-activated receptors (PARs). We took advantage of the lack of b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d43669519b81c8d6853c718c7987ecf
https://doi.org/10.1152/ajpgi.00444.2007

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Longitudinal Analysis of Gene Expression in Porcine Skeletal Muscle After Post-Injection Local Injury

Autor: Pierre-Louis Toutain, François Hatey, Pierre J. Ferré, Magali SanCristobal, Agnès Bonnet, Gwenola Tosser-Klopp, Laurence Liaubet, Didier Concordet, Emmanuelle Uro-Coste, Hervé P. Lefebvre

Publikováno v: Pharmaceutical Research
Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2007, 24 (8), pp.1480-9. ⟨10.1007/s11095-007-9266-8⟩
Pharmaceutical Research, 2007, 24 (8), pp.1480-9. ⟨10.1007/s11095-007-9266-8⟩
Pharmaceutical Research / Pharmaceutical Research (Dordrecht)
Pharmaceutical Research / Pharmaceutical Research (Dordrecht), 2007, 24 (8), pp.1480-9. ⟨10.1007/s11095-007-9266-8⟩

International audience; PURPOSE: The purpose of this study is to describe the time course of gene expression in a skeletal muscle local injury induced by an intramuscular (IM) injection, and to compare the dynamics of gene expression with pathologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b9ba314b202f22100ab07f58a190e6
https://doi.org/10.1007/s11095-007-9266-8

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Elastin-Derived Peptides Upregulate Matrix Metalloproteinase-2-ediated Melanoma Cell Invasion Through Elastin-Binding Protein

Autor: Romain Debret, Philipe Birembaut, Philipe Bernard, Frank Antonicelli, William Hornebeck, Anne-Laure Labrousse, Georges Bellon, Carole Ntayi

Publikováno v: Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2004, 122 (2), pp.256-65. ⟨10.1046/j.0022-202X.2004.22228.x⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2004, 122 (2), pp.256-265. ⟨10.1046/j.0022-202X.2004.22228.x⟩
Journal of Investigative Dermatology, 2004, 122 (2), pp.256-65. ⟨10.1046/j.0022-202X.2004.22228.x⟩

International audience; Type I collagen mediates melanoma cells invasion through upregulation of matrix metalloproteinases-1 and -2 (MMP-1 and -2) expression and activation. We investigated here the contribution of elastin-derived peptides (ED), degr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0d56e33b946f2a69b7105e59b64669

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Down-Regulation of MT1-MMP Expression by the α3 Chain of Type IV Collagen Inhibits Bronchial Tumor Cell Line Invasion

Autor: Agnès Noël, Jean-Claude Monboisse, Jean-Michel Foidart, Alain Colige, Pierre Dehan, Laurette Volders, Myriam Polette, Christine Gilles, Corinne Martinella-Catusse, Philippe Birembaut, Carine Munaut

Publikováno v: Scopus-Elsevier
Laboratory Investigation
Laboratory Investigation, Nature Publishing Group, 2001, 81 (2), pp.167-75
Laboratory Investigation, 2001, 81 (2), pp.167-75

International audience; The basement membrane (BM) is the first barrier encountered by tumor cells when they become invasive. Moreover, some invasive tumor clusters are surrounded by a remnant or neosynthetized BM material. We have previously reporte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6a1827f593adb16dcd42331c137a33
https://doi.org/10.1038/labinvest.3780224

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Quantitative cell dispersion analysis: New test to measure tumor cell aggressiveness

Autor: Jean-Marie Zahm, Beatrice Raby, Kristin Strumane, Frans van Roy, Philippe Birembaut, Noël Bonnet, Myriam Polette, Christine Gilles, Manuela Matos, Christine Clavel

Publikováno v: International Journal of Cancer
International Journal of Cancer, Wiley, 2001, 93 (5), pp.644-52
International Journal of Cancer, 2001, 93 (5), pp.644-52

Tumor progression requires the dispersion of epithelial cells from neoplastic clusters and cell invasion of adjacent stromal connective tissue. Aiming at demonstrating the precise relationships between cell dispersion and cell invasion, related respe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d302e3ac07387e7f35ead830d6b99694
https://doi.org/10.1002/ijc.1380

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Long-term effects of HTLV-1 on brain astrocytes: Sustained expression of Tax-1 associated with synthesis of inflammatory mediators

Autor: Pascale Giraudon, Christine Brisson, Hideo Akaoka, Raphaël Szymocha, Arlette Bernard, Marie-Françoise Belin

Publikováno v: Journal of NeuroVirology
Journal of NeuroVirology, Springer Verlag, 2000, 6 (4), pp.350-357. ⟨10.3109/13550280009030761⟩

International audience; HTLV-1 is the causative agent of a chronic neurological disease, TSP/HAM. The persistently activated CTL response to the viral protein Tax-1 suggests the existence of persistent viral replication with continuous expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6575b1c53d5c2fe0a573e676c79f426
https://doi.org/10.3109/13550280009030761

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The matrix metalloproteinase inhibitor marimastat promotes neural progenitor cell differentiation into neurons by gelatinase-independent TIMP-2-dependent mechanisms

Autor: Pasquale Caramanica, Luisa Minghetti, Emanuele Cacci, Virginia Medda, Maria Antonietta Ajmone-Cat, Ferdinando Mannello, Maddalena Sinno, Gaetana A. Tonti, Stefano Biagioni, Irene Pafumi

Publikováno v: Stem Cells and Development
Stem Cells and Development, Mary Ann Liebert, 2013, 22 (3), pp.345-58. ⟨10.1089/scd.2012.0299⟩

International audience; Metalloproteinases (MMPs) and their endogenous inhibitors (TIMPs), produced in the brain by cells of non-neural and neural origin, including neural progenitors (NPs), are emerging as regulators of nervous system development an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a46a9e84e88c47f590306c49d7521c
https://hal-riip.archives-ouvertes.fr/pasteur-00974731/document

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A key role for matrix metalloproteinases and neutral sphingomyelinase-2 in transplant vasculopathy triggered by anti-HLA antibody

Autor: Anne Nègre-Salvayre, Magali Trayssac, Jean-Claude Thiers, Lionel Rostaing, Sylvain Galvani, Nassim Kamar, Hans-Willi Krell, Robert Salvayre, Mogens Thomsen, Federico Sallusto, Denis Calise, Nathalie Augé

Publikováno v: Circulation
Circulation, American Heart Association, 2011, 124 (24), pp.2725-34. ⟨10.1161/CIRCULATIONAHA.111.021790⟩
Circulation, 2011, 124 (24), pp.2725-34. ⟨10.1161/CIRCULATIONAHA.111.021790⟩
Circulation, American Heart Association, 2011, 124 (24), pp.2725-2734. ⟨10.1161/CIRCULATIONAHA.111.021790⟩

Background— Outcomes for organ transplantation are constantly improving because of advances in organ preservation, surgical techniques, immune clinical monitoring, and immunosuppressive treatment preventing acute transplant rejection. However, chro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704d9726a1bdd1816c147a68a8e73f10
https://www.hal.inserm.fr/inserm-00726866

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