Zobrazeno 1 - 10
of 34
pro vyhledávání: '"MESH: Macrolides"'
Autor:
Sébastien Bridel, Valérie Bouchez, Bryan Brancotte, Sofia Hauck, Nathalie Armatys, Annie Landier, Estelle Mühle, Sophie Guillot, Julie Toubiana, Martin C. J. Maiden, Keith A. Jolley, Sylvain Brisse
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.3807. ⟨10.1038/s41467-022-31517-8⟩
Nature Communications, 2022, 13 (1), pp.3807. ⟨10.1038/s41467-022-31517-8⟩
The genus Bordetella includes bacteria that are found in the environment and/or associated with humans and other animals. A few closely related species, including Bordetella pertussis, are human pathogens that cause diseases such as whooping cough. H
Publikováno v:
Methods in Molecular Biology ISBN: 9781071617786
Mycobacterium ulcerans
Mycobacterium ulcerans, 2387, Springer US, pp.163-181, 2021, Methods in Molecular Biology, 978-1-0716-1779-3. ⟨10.1007/978-1-0716-1779-3_16⟩
Mycobacterium ulcerans
Mycobacterium ulcerans, 2387, Springer US, pp.163-181, 2021, Methods in Molecular Biology, 978-1-0716-1779-3. ⟨10.1007/978-1-0716-1779-3_16⟩
International audience; Mycobacterium ulcerans, the causative agent of Buruli ulcer disease, is unique among human pathogens in its capacity to produce mycolactone, a diffusible macrolide with immunosuppressive and cytotoxic properties. Recent studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c4e489b2a041e081d727368f55d042
https://doi.org/10.1007/978-1-0716-1779-3_16
https://doi.org/10.1007/978-1-0716-1779-3_16
Publikováno v:
Toxicology Letters
Toxicology Letters, Elsevier, 2021, 351, pp.89-98. ⟨10.1016/j.toxlet.2021.08.013⟩
Toxicology Letters, Elsevier, 2021, 351, pp.89-98. ⟨10.1016/j.toxlet.2021.08.013⟩
International audience; Lipophilic phycotoxins are secondary metabolites produced by phytoplankton. They can accumulate in edible filtering-shellfish and cause human intoxications, particularly gastrointestinal symptoms. Up to now, the in vitro intes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d389612e7ee2de4301eef0d287efe327
https://hal-anses.archives-ouvertes.fr/anses-03378478
https://hal-anses.archives-ouvertes.fr/anses-03378478
Autor:
A. B. Zimenkovsky, Oksana Horodnycha
Publikováno v:
Pharmacy Practice (Granada) v.19 n.1 2021
SciELO España: Revistas Científicas Españolas de Ciencias de la Salud
Instituto de Salud Carlos III (ISCIII)
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Pharmacy Practice, Vol 19, Iss 1, p 2055 (2021)
Pharmacy Practice
SciELO España: Revistas Científicas Españolas de Ciencias de la Salud
Instituto de Salud Carlos III (ISCIII)
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Pharmacy Practice, Vol 19, Iss 1, p 2055 (2021)
Pharmacy Practice
Background: Antibiotic allergy is an important clinical and social-economical issue. Objective: The main objectives of this study were to determine the incidence, causative drugs, and risk groups of antibiotic allergy as a reason for hospitalization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c8e7935e8233f6e274a6fe092d15d1
http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1885-642X2021000100002
http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1885-642X2021000100002
Publikováno v:
Mycobacterium ulcerans
Mycobacterium ulcerans, 2387, Springer US, pp.117-130, 2021, Methods in Molecular Biology, 978-1-0716-1779-3. ⟨10.1007/978-1-0716-1779-3_13⟩
Methods in Molecular Biology ISBN: 9781071617786
Mycobacterium ulcerans, 2387, Springer US, pp.117-130, 2021, Methods in Molecular Biology, 978-1-0716-1779-3. ⟨10.1007/978-1-0716-1779-3_13⟩
Methods in Molecular Biology ISBN: 9781071617786
International audience; Mycolactones are a family of polyketide synthase products made by the human pathogen Mycobacterium ulcerans that were recently identified as novel inhibitors of the host membrane translocation complex (Sec61). Here, we provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b757b32f6288a56f3464bfe25f2dd34e
https://hal-pasteur.archives-ouvertes.fr/pasteur-03534701
https://hal-pasteur.archives-ouvertes.fr/pasteur-03534701
Autor:
Caroline, Demangel, Stephen, High
Publikováno v:
Biology of the Cell
Biology of the Cell, 2018, 110 (11), pp.237-248. ⟨10.1111/boc.201800030⟩
Biology of the Cell, 2018, 110 (11), pp.237-248. ⟨10.1111/boc.201800030⟩
International audience; Infection with Mycobacterium ulcerans results in a necrotising skin disease known as a Buruli ulcer, the pathology of which is directly linked to the bacterial production of the toxin mycolactone. Recent studies have identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::56ac8b06b7916ac95b0ce4c34e171b69
https://doi.org/10.1111/boc.201800030
https://doi.org/10.1111/boc.201800030
Autor:
Isaac, Caroline, Mauborgne, Annie, Grimaldi, Alfonso, Ade, Kemy, Pohl, Michel, Limatola, Cristina, Boucher, Yves, Demangel, Caroline, Guenin-Macé, Laure
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, 2017, 11 (11), pp.e0006058. ⟨10.1371/journal.pntd.0006058⟩
PLoS Neglected Tropical Diseases, Vol 11, Iss 11, p e0006058 (2017)
PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (11), pp.e0006058. ⟨10.1371/journal.pntd.0006058⟩
PLoS Neglected Tropical Diseases, 2017, 11 (11), pp.e0006058. ⟨10.1371/journal.pntd.0006058⟩
PLoS Neglected Tropical Diseases, Vol 11, Iss 11, p e0006058 (2017)
PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (11), pp.e0006058. ⟨10.1371/journal.pntd.0006058⟩
Background Mycolactone is a macrolide produced by the skin pathogen Mycobacterium ulcerans, with cytotoxic, analgesic and immunomodulatory properties. The latter were recently shown to result from mycolactone blocking the Sec61-dependent production o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c1ffaad477ce068c6ad7c755f65d1713
https://doi.org/10.1371/journal.pntd.0006058
https://doi.org/10.1371/journal.pntd.0006058
Autor:
Sophie Hidalgo-Lucas, Georges Bismuth, Jean-François Bisson, Laure Guenin-Macé, Sarah Saint-Auret, Cédric Tresse, Fabien Le Chevalier, Caroline Demangel, Pierre Bruhns, Ludivine Baron, Nicolas Blanchard, Friederike Jönsson, Anne-Caroline Chany
Publikováno v:
Science Translational Medicine
Science Translational Medicine, 2015, 7 (289), pp.289ra85-289ra85. ⟨10.1126/scitranslmed.aab0458⟩
Science Translational Medicine, American Association for the Advancement of Science, 2015, 7 (289), pp.289ra85-289ra85. 〈10.1126/scitranslmed.aab0458〉
Science Translational Medicine, American Association for the Advancement of Science, 2015, 7 (289), pp.289ra85-289ra85. ⟨10.1126/scitranslmed.aab0458⟩
Science Translational Medicine, 2015, 7 (289), pp.289ra85-289ra85. ⟨10.1126/scitranslmed.aab0458⟩
Science Translational Medicine, American Association for the Advancement of Science, 2015, 7 (289), pp.289ra85-289ra85. 〈10.1126/scitranslmed.aab0458〉
Science Translational Medicine, American Association for the Advancement of Science, 2015, 7 (289), pp.289ra85-289ra85. ⟨10.1126/scitranslmed.aab0458⟩
International audience; Inflammation adversely affects the health of millions of people worldwide, and there is an unmet medical need for better anti-inflammatory drugs. We evaluated the therapeutic interest of mycolactone, a polyketide-derived macro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515e3e0e604c57dc804f3e80b4b4c2c8
https://doi.org/10.1126/scitranslmed.aab0458
https://doi.org/10.1126/scitranslmed.aab0458
Autor:
Reiko Ueoka, Silke Reiter, Agustinus Robert Uria, Petra Karbaum, Shigeki Matsunaga, Tetsushi Mori, Morinaka Gugger, Brandon I. Morinaka, Eike E. Peters, Jörn Piel, Eric J. N. Helfrich, Haruko Takeyama
Publikováno v:
Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2015, 11 (9), pp.705-712. ⟨10.1038/nCHeMBIO.1870⟩
Nature Chemical Biology, 2015, 11 (9), pp.705-712. ⟨10.1038/nCHeMBIO.1870⟩
Nature chemical biology
Nature Chemical Biology, Nature Publishing Group, 2015, 11 (9), pp.705-712. ⟨10.1038/nCHeMBIO.1870⟩
Nature Chemical Biology, 2015, 11 (9), pp.705-712. ⟨10.1038/nCHeMBIO.1870⟩
Nature chemical biology
International audience; Actin-targeting macrolides comprise a large, structurally diverse group of cytotoxins isolated from remarkably dissimilar micro- and macroorganisms. In spite of their disparate origins and structures, many of these compounds b
Autor:
Eva Kaiser, Klaus Aktories, Johannes Buchner, Carsten Schwan, Michel R. Popoff, Katharina Ernst, Claudia Kroll, Gunter Fischer, Holger Barth
Publikováno v:
Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2011, 79 (10), pp.3913-3921. 〈10.1128/IAI.05372-11〉
Infection and Immunity, American Society for Microbiology, 2011, 79 (10), pp.3913-3921. ⟨10.1128/IAI.05372-11⟩
Infection and Immunity, 2011, 79 (10), pp.3913-3921. ⟨10.1128/IAI.05372-11⟩
Infection and Immunity, American Society for Microbiology, 2011, 79 (10), pp.3913-3921. 〈10.1128/IAI.05372-11〉
Infection and Immunity, American Society for Microbiology, 2011, 79 (10), pp.3913-3921. ⟨10.1128/IAI.05372-11⟩
Infection and Immunity, 2011, 79 (10), pp.3913-3921. ⟨10.1128/IAI.05372-11⟩
Some hypervirulent strains of Clostridium difficile produce the binary actin-ADP-ribosylating toxin C. difficile transferase (CDT) in addition to Rho-glucosylating toxins A and B. It has been suggested that the presence of CDT increases the severity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b63619bc204247a48574823e9c1276
https://hal-pasteur.archives-ouvertes.fr/pasteur-01762530
https://hal-pasteur.archives-ouvertes.fr/pasteur-01762530