Mapping and Characterization of HCMV-Specific Unconventional HLA-E-Restricted CD8 T Cell Populations and Associated NK and T Cell Responses Using HLA/Peptide Tetramers and Spectral Flow Cytometry

Autor: Amélie Rousselière, Laurence Delbos, Céline Bressollette, Maïlys Berthaume, Béatrice Charreau

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 263, p 263 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 263
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 23 (1), pp.263. ⟨10.3390/ijms23010263⟩

HCMV drives complex and multiple cellular immune responses, which causes a persistent immune imprint in hosts. This study aimed to achieve both a quantitative determination of the frequency for various anti-HCMV immune cell subsets, including CD8 T,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c251519185848aca94e1699be5c0f0b
https://doi.org/10.3390/ijms23010263

Homeostasis of Peripheral CD4+ T Cells: IL-2Rα and IL-2 Shape a Population of Regulatory Cells That Controls CD4+ T Cell Numbers

Autor: Martine Papiernik, Afonso R. M. Almeida, Antonio A. Freitas, Nicolas Legrand

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2002, 169 (9), pp.4850-60. ⟨10.4049/jimmunol.169.9.4850⟩
Journal of Immunology, 2002, 169 (9), pp.4850-60. ⟨10.4049/jimmunol.169.9.4850⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2002, 169 (9), pp.4850-60
Journal of immunology (Baltimore, Md., 169(9), 4850-4860. American Association of Immunologists

We show that the lymphoid hyperplasia observed in IL-2Rα- and IL-2-deficient mice is due to the lack of a population of regulatory cells essential for CD4 T cell homeostasis. In chimeras reconstituted with bone marrow cells from IL-2Rα-deficient do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5dd88a962005b9b0c7e534bc0c70aa
https://doi.org/10.4049/jimmunol.169.9.4850

The Extended Clinical Phenotype Of 64 Patients With Dedicator Of Cytokinesis 8 Deficiency

Autor: Tim Niehues, Karin R. Engelhardt, Mehmet Kilic, Raif S. Geha, Necil Kutukculer, Zeina Baz, Sevgi Keles, Cristina Glocker, Caner Aytekin, Ozden Sanal, Ismail Reisli, Zahra Pourpak, Ferah Genel, Mustafa Yilmaz, Alison Jones, B Gaspar, Elena C. Sigmund, Nermeen Galal, Yildiz Camcioglu, Michel J. Massaad, Amos Etzioni, Turkan Patiroglu, Laura E. Graham, Maria Cristina Pietrogrande, Majed Dasouki, Andrew R. Gennery, S Weinspach, G Dueckers, Michael E. Gertz, Monia Khemiri, M. R. Barbouche, Mehdi Yeganeh, Imen Ben-Mustapha, Shiva Saghafi, Bodo Grimbacher, Salem Al-Tamemi, Andrew J. Cant, A. Sassi, Gérard Lefranc, Ayse Metin, Vassilios Lougaris, Ayper Somer, Fethi Mellouli, Ekrem Unal, Alexandra F. Freeman, Jeannette Boutros, Ruben Ceja, Jens Thiel, André Mégarbané, Sara Sebnem Kilic, Talal A. Chatila, Mohamed Bejaoui, Alejandro A. Schäffer, Ilhan Tezcan, Waleed Al-Herz, Peter D. Arkwright, Ilka Schulze

Publikováno v: Journal of Allergy and Clinical Immunology: In Practice
Journal of Allergy and Clinical Immunology: In Practice, Elsevier, 2015, 136 (2), pp.402-12. ⟨10.1016/j.jaci.2014.12.1945⟩

PubMedID: 25724123 Background Mutations in dedicator of cytokinesis 8 (DOCK8) cause a combined immunodeficiency (CID) also classified as autosomal recessive (AR) hyper-IgE syndrome (HIES). Recognizing patients with CID/HIES is of clinical importance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d8b23abc6c5a5d7f77d7ae3893d473
http://hdl.handle.net/11655/14451

Increase of CD4+ CD25+ regulatory T cells in the peripheral blood of patients with metastatic carcinoma: a Phase I clinical trial using cyclophosphamide and immunotherapy to eliminate CD4+ CD25+ T lymphocytes

Autor: Dominique Cathelin, L. Arnould, Sylvain Audia, Christophe Ferrand, Nicolas Larmonier, Bernard Bonnotte, Bruno Chauffert, Marc Maynadié, Alexandra Nicolas, Eric Solary, A L Fanton, P. Foucher, Andrew Bateman, B. Lorcerie, E. Bergoin

Publikováno v: Clinical and Experimental Immunology
Clinical and Experimental Immunology, Wiley, 2007, 150 (3), pp.523-30. 〈10.1111/j.1365-2249.2007.03521.x〉
Clinical and Experimental Immunology, 2007, 150 (3), pp.523-30. ⟨10.1111/j.1365-2249.2007.03521.x⟩
Clinical and Experimental Immunology, Wiley, 2007, 150 (3), pp.523-30. ⟨10.1111/j.1365-2249.2007.03521.x⟩

SummaryWe determined the number and functional status of CD4+CD25high regulatory T cells (Treg) in blood samples from patients with metastatic carcinoma, and evaluated their sensitivity to a single intravenous infusion of cyclophosphamide. Treg numbe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ce52429df457234d7101abc659f311
http://www.hal.inserm.fr/inserm-00479739

Lymphocyte subset reconstitution after unrelated cord blood or bone marrow transplantation in children

Autor: Rénard, C., Barlogis, V., Mialou, V., Galambrun, C., Bernoux, D., Goutagny, Mp, Glasman, L., Loundou, Ad, Poitevin-Later, F., Dignat-George, Francoise, Dubois, V., Picard, C., Chabannon, C., Bertrand, Yves, Michel, G.

Publikováno v: Br J Haematol.
Br J Haematol., 2011, 152 (3), pp.322-30. ⟨10.1111/j.1365-2141.2010.08409.x⟩

International audience; We report the post-transplant lymphocyte subset recovery of 226 children treated with Unrelated Cord Blood transplant (UCBT) (n = 112) or Unrelated Bone Marrow Transplant (UBMT) (n = 114) for malignant or non-malignant disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eda994fb425434dbc097eab5420c7f86
https://hal.science/hal-00679257