Zobrazeno 1 - 10
of 25
pro vyhledávání: '"MESH: Long QT Syndrome"'
Publikováno v:
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, Wiley, In press, ⟨10.1111/bcp.15188⟩
British Journal of Clinical Pharmacology, Wiley, In press, ⟨10.1111/bcp.15188⟩
International audience; The extent of sotalol-induced QTc prolongation on the electrocardiogram, is variable among subjects and influenced by sex. However, the influence of baseline QTc on the extent of drug-induced QTc prolongation remains unclear.
Autor:
Frank Bellivier, François Naccache, Vanessa Bloch, Jean Pierre Lepine, Florence Vorspan, Stéphane Mouly, Andries T. Marees, Cynthia Marie-Claire, Nathalie Prince, Jean-Louis Laplanche, El Hadi Zerdazi
Publikováno v:
Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 2018, ⟨10.1111/fcp.12405⟩
Fundamental and Clinical Pharmacology, 33(1), 96-106. Wiley-Blackwell
Fundamental and Clinical Pharmacology, Wiley, 2019, 33 (1), pp.96-106. ⟨10.1111/fcp.12405⟩
Zerdazi, E H, Vorspan, F, Marees, A T, Naccache, F, Lepine, J P, Laplanche, J L, Prince, N, Marie-Claire, C, Bellivier, F, Mouly, S & Bloch, V 2019, ' QT length during methadone maintenance treatment: gene × dose interaction ', Fundamental and Clinical Pharmacology, vol. 33, no. 1, pp. 96-106 . https://doi.org/10.1111/fcp.12405
Fundamental & clinical pharmacology, 33(1), 96-106. Wiley-Blackwell
Fundamental & Clinical Pharmacology
Fundamental & Clinical Pharmacology, 2018, 33 (1), pp.96-106. ⟨10.1111/fcp.12405⟩
Fundamental and Clinical Pharmacology, Wiley, 2018, ⟨10.1111/fcp.12405⟩
Fundamental and Clinical Pharmacology, 33(1), 96-106. Wiley-Blackwell
Fundamental and Clinical Pharmacology, Wiley, 2019, 33 (1), pp.96-106. ⟨10.1111/fcp.12405⟩
Zerdazi, E H, Vorspan, F, Marees, A T, Naccache, F, Lepine, J P, Laplanche, J L, Prince, N, Marie-Claire, C, Bellivier, F, Mouly, S & Bloch, V 2019, ' QT length during methadone maintenance treatment: gene × dose interaction ', Fundamental and Clinical Pharmacology, vol. 33, no. 1, pp. 96-106 . https://doi.org/10.1111/fcp.12405
Fundamental & clinical pharmacology, 33(1), 96-106. Wiley-Blackwell
Fundamental & Clinical Pharmacology
Fundamental & Clinical Pharmacology, 2018, 33 (1), pp.96-106. ⟨10.1111/fcp.12405⟩
Methadone is known to be a risk factor for sudden death by enlarging ECG QT corrected (QTc) interval. For other medical conditions, QTc lengthening has been described as the result of interactions between pharmacological treatments and genetic factor
Autor:
Antoine Leenhardt, Cindy Colson, Hervé Mittre, Adeline Busson, Yann Troadec, Isabelle Denjoy, Véronique Fressard
Publikováno v:
European Journal of Medical Genetics
European Journal of Medical Genetics, Elsevier, 2019, 62 (7), pp.103648. ⟨10.1016/j.ejmg.2019.04.005⟩
European Journal of Medical Genetics, Elsevier, 2019, 62 (7), pp.103648. ⟨10.1016/j.ejmg.2019.04.005⟩
International audience; CANAC1C encodes for the main cardiac L-type calcium channel and mutations on it lead to a prolonged QT interval in Timothy Syndrome (TS). We provide a new de novo constitutional heterozygote missense variation in CACNA1C in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1a6a5b4fa11da8a1a0492cd867db4c
https://hal.archives-ouvertes.fr/hal-02393710/document
https://hal.archives-ouvertes.fr/hal-02393710/document
Publikováno v:
Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology
Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology, Elsevier, 2016, 183-184, pp.53-60. ⟨10.1016/j.cbpc.2016.01.006⟩
Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology, Elsevier, 2016, 183-184, pp.53-60. ⟨10.1016/j.cbpc.2016.01.006⟩
International audience; The QT interval of the electrocardiogram (ECG) is a measure of the duration of the ventricular depolarization and repolarization. In fish as in human, the QT interval is positively correlated with the RR interval of the ECG, a
Autor:
Hugues Abriel, Heidi Fodstad, Saïd Bendahhou, Jacques Barhanin, Heikki Swan, Laurent Schild, Kimmo Kontula, Jean-Sébastien Rougier, Päivi J. Laitinen-Forsblom
Publikováno v:
Annals of Medicine
Annals of Medicine, Taylor & Francis, 2006, 38 (4), pp.294-304. ⟨10.1080/07853890600756065⟩
Annals of Medicine, Taylor & Francis, 2006, 38 (4), pp.294-304. ⟨10.1080/07853890600756065⟩
BACKGROUND: Mutations of at least six different genes have been found to cause long QT syndrome (LQTS), an inherited arrhythmic disorder characterized by a prolonged QT interval on the electrocardiogram (ECG), ventricular arrhythmias and risk of sudd
Publikováno v:
Journal of Electrocardiology
Journal of Electrocardiology, Elsevier, 1995, 28, pp.138-142. ⟨10.1016/s0022-0736(95)80039-5⟩
Journal of Electrocardiology, Elsevier, 1995, 28, pp.138-142. ⟨10.1016/s0022-0736(95)80039-5⟩
International audience
Autor:
Ducroq, Joffrey, Moha Ou Maati, H., Guilbot, S., Dilly, S., Laemmel, E., Pons-Himbert, C., Faivre, J. F., Bois, P., Stücker, O., Le Grand, M.
Publikováno v:
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2010, 159 (1), pp.93-101. ⟨10.1111/j.1476-5381.2009.00371.x⟩
British Journal of Pharmacology, Wiley, 2010, 159 (1), pp.93-101. ⟨10.1111/j.1476-5381.2009.00371.x⟩
Doxorubicin, an anthracycline widely used in the treatment of a broad range of tumours, causes acute QT prolongation. Dexrazoxane has been shown to prevent the QT prolongation induced by another anthracycline, epirubicin, but has not yet been reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::54b9d8ce869e7aa31273aaaece6c3569
https://hal.archives-ouvertes.fr/hal-00561579
https://hal.archives-ouvertes.fr/hal-00561579
Autor:
Keller, Dagmar, Grenier, Julie, Christé, Georges, Dubouloz, Frédérique, Osswald, Stephan, Brink, Marijke, Ficker, Eckhard, Chahine, Mohamed
Publikováno v:
Canadian Journal of Cardiology
Canadian Journal of Cardiology, Elsevier, 2009, 25 (8), pp.455-62
Canadian Journal of Cardiology, Elsevier, 2009, 25 (8), pp.455-62
International audience; BACKGROUND: Long QT syndrome (LQTS) is characterized by corrected QT interval prolongation leading to torsades de pointes and sudden cardiac death. LQTS type 2 (LQTS2) is caused by mutations in the KCNH2 gene, leading to a red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______212::d5bbc6cd72c5503f3c1b252050476c2f
https://www.hal.inserm.fr/inserm-00409709/file/Keller-D_2009_Can_J_Cardiol.pdf
https://www.hal.inserm.fr/inserm-00409709/file/Keller-D_2009_Can_J_Cardiol.pdf
Autor:
Keller, Dagmar, Grenier, Julie, Christé, Georges, Dubouloz, Frédérique, Osswald, Stephan, Brink, Marijke, Ficker, Eckhard, Chahine, Mohamed
Publikováno v:
Canadian Journal of Cardiology
Canadian Journal of Cardiology, Elsevier, 2009, 25 (8), pp.455-62
Canadian Journal of Cardiology, Elsevier, 2009, 25 (8), pp.455-62
International audience; BACKGROUND: Long QT syndrome (LQTS) is characterized by corrected QT interval prolongation leading to torsades de pointes and sudden cardiac death. LQTS type 2 (LQTS2) is caused by mutations in the KCNH2 gene, leading to a red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::d5bbc6cd72c5503f3c1b252050476c2f
https://www.hal.inserm.fr/inserm-00409709/file/Keller-D_2009_Can_J_Cardiol.pdf
https://www.hal.inserm.fr/inserm-00409709/file/Keller-D_2009_Can_J_Cardiol.pdf
Autor:
Frédéric Treguer, Remi Baruteau, Raphaël P. Martins, Philippe Mabo, Alban-Elouen Baruteau, Ryad Joomye, Jean-Claude Daubert, Julien Baruteau, Michel Roussey
Publikováno v:
European Journal of Pediatrics
European Journal of Pediatrics, Springer Verlag, 2009, 168 (7), pp.771-7. ⟨10.1007/s00431-009-0951-y⟩
European Journal of Pediatrics, 2009, 168 (7), pp.771-7. ⟨10.1007/s00431-009-0951-y⟩
European Journal of Pediatrics, Springer Verlag, 2009, 168 (7), pp.771-7. ⟨10.1007/s00431-009-0951-y⟩
European Journal of Pediatrics, 2009, 168 (7), pp.771-7. ⟨10.1007/s00431-009-0951-y⟩
International audience; INTRODUCTION: Congenital long-QT syndrome (LQTS) is a sporadic or familial inherited arrhythmia. It can lead to sudden death by ventricular fibrillation which occurs at any age but particularly during infancy. Recent studies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85170520ca0f4131b0dff28c6b4cda0
https://hal.archives-ouvertes.fr/hal-00911293
https://hal.archives-ouvertes.fr/hal-00911293