Genomic modeling of tumor onset and progression in a mouse model of aggressive human liver cancer

Autor: Snorri S. Thorgeirsson, Elizabeth A. Conner, Valentina M. Factor, Cédric Coulouarn

Publikováno v: Carcinogenesis
Carcinogenesis, Oxford University Press (OUP), 2011, 32 (10), pp.1434-40. ⟨10.1093/carcin/bgr133⟩
Carcinogenesis, 2011, 32 (10), pp.1434-40. ⟨10.1093/carcin/bgr133⟩

International audience; A comprehensive understanding of molecular mechanisms driving cancer onset and progression should provide a basis for improving early diagnosis, biomarker discovery and treatment options. A key value of genetically engineered

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3142c0aca7b31d360d162a560bedea
https://doi.org/10.1093/carcin/bgr133

Hepatocyte Nuclear Factor 4 Expression Overcomes Repression of the Hepatic Phenotype in Dedifferentiated Hepatoma Cells

Autor: Gerald F. Späth, Mary C. Weiss

Publikováno v: Molecular and Cellular Biology
Molecular and Cellular Biology, 1997, 17 (4), pp.1913-1922. ⟨10.1128/mcb.17.4.1913⟩
Molecular and Cellular Biology, American Society for Microbiology, 1997, 17 (4), pp.1913-1922. ⟨10.1128/mcb.17.4.1913⟩

International audience; The capacity of the liver-enriched transcription factor hepatocyte nuclear factor 4 (HNF4) to direct redifferentiation of dedifferentiated rat hepatoma cells was investigated by stable transfection of epitope-tagged HNF4 cDNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd188dde90aaa77df6c5450720d2d1c
https://doi.org/10.1128/mcb.17.4.1913

Optimization of hepatocarcinoma uptake with radiolabeled lipiodol: development of new lipiodol formulations with increased viscosity

Autor: Etienne Garin, Virginie Cadeillan, Valérie Ardisson, Sahar Bayat, Nicolas Lepareur, Stéphanie Becker, Nicolas Noiret

Publikováno v: Cancer Biotherapy and Radiopharmaceuticals
Cancer Biotherapy and Radiopharmaceuticals, Mary Ann Liebert, 2012, 27 (2), pp.149-55. ⟨10.1089/cbr.2011.1072⟩
Cancer Biotherapy and Radiopharmaceuticals, 2012, 27 (2), pp.149-55. ⟨10.1089/cbr.2011.1072⟩

International audience; The aim of this study was to develop new Lipiodol formulations with increased viscosities to augment Lipiodol embolic effect and optimize efficiency of radiolabeled Lipiodol in hepatocarcinoma treatments. New Lipiodol formulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf52c06c4702f2b0e145761757946a20
https://hal.archives-ouvertes.fr/hal-00867018

3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells

Autor: Xavier Tekpli, David H. Phillips, Volker M. Arlt, Magne Refsnes, Nina E. Landvik, Anita Solhaug, Dominique Lagadic-Gossmann, Eszter Nagy, Heinz H. Schmeiser, Jørn A. Holme

Publikováno v: Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis
Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, Elsevier, 2010, 684 (1-2), pp.11-23. ⟨10.1016/j.mrfmmm.2009.11.004⟩
Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2010, 684 (1-2), pp.11-23. ⟨10.1016/j.mrfmmm.2009.11.004⟩

3-Nitrobenzanthrone (3-NBA) is a mutagenic and carcinogenic environmental pollutant found in diesel exhaust and urban air pollution. In the present work we have characterised the effects of 3-NBA and its metabolite 3-aminobenzanthrone (3-ABA) on cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c89a0852fee62ad61dfe8cbf3a144e22

ATP7B copper-regulated traffic and association with the tight junctions: copper excretion into the bile.: ATP7B and copper excretion by liver

Autor: Hernandez, Sonia, Tsuchiya, Yo, García-Ruiz, Josefa, Lalioti, Vassiliki, Nielsen, Søren, Cassio, Doris, Sandoval, Ignacio

Publikováno v: Gastroenterology
Gastroenterology, Elsevier, 2008, 134 (4), pp.1215-23. ⟨10.1053/j.gastro.2008.01.043⟩

International audience; BACKGROUND & AIMS: The copper transporter ATP7B plays a central role in the elimination of excess copper by the liver into the bile, yet the site of its action remains controversial. The studies reported here examine the corre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::147c0a11f67274585adb9b62b367b6d1
https://www.hal.inserm.fr/inserm-00276812/file/Hernandez_2008_gastro.pdf_-1.pdf