Výsledky vyhledávání - "MESH: Leptin"

Body fat distribution in Parkinson's disease: An MRI-based body fat quantification study

Autor: Jan Kassubek, Albert C. Ludolph, Hans-Peter Müller, Denise Bernhardt, Luc Dupuis

Publikováno v: Parkinsonism and Related Disorders
Parkinsonism and Related Disorders, Elsevier, 2016, 33 (8), pp.84-89. ⟨10.1016/j.parkreldis.2016.09.016⟩
Parkinsonism & Related Disorders
Parkinsonism & Related Disorders, 2016, 33 (8), pp.84-89. ⟨10.1016/j.parkreldis.2016.09.016⟩

International audience; Introduction: There is some evidence that Parkinson's Disease (PD) patients have lower body weight and lower fat mass when compared to healthy subjects and that lower body weight and fat mass influence disease risk and progres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38940514aada868424d25247f255e7de
https://www.hal.inserm.fr/inserm-03375200/document

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Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver

Autor: Julie Massart, Bernard Fromenty, Annie Borgne-Sanchez, Karima Begriche, Marie-Anne Robin

Publikováno v: Journal of Hepatology
Journal of Hepatology, Elsevier, 2011, 54 (4), pp.773-94. ⟨10.1016/j.jhep.2010.11.006⟩
Journal of Hepatology, 2011, 54 (4), pp.773-94. ⟨10.1016/j.jhep.2010.11.006⟩

International audience; Numerous investigations have shown that mitochondrial dysfunction is a major mechanism of drug-induced liver injury, which involves the parent drug or a reactive metabolite generated through cytochromes P450. Depending of thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f582fbb934f743d1cbea6662b615fd
https://doi.org/10.1016/j.jhep.2010.11.006

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Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity

Autor: G Lacraz, Louis Hue, Bruno Guigas, I De Potter, Roland Favier, Nellie Taleux, Xavier Leverve, C Deransart

Publikováno v: International Journal of Obesity
International Journal of Obesity, Nature Publishing Group, 2008, 32 (4), pp.639-47. ⟨10.1038/sj.ijo.0803759⟩

International audience; OBJECTIVE: The AMP-activated protein kinase (AMPK) is involved in the control of food intake by the hypothalamus. The aim of this work was to investigate if modification of hypothalamic AMPK regulation could be related to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03115caafd17e78f82420a389eac8a81
https://doi.org/10.1038/sj.ijo.0803759

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Sex Differences in Lipolysis-Regulating Mechanisms in Overweight Subjects: Effect of Exercise Intensity*

Autor: François Crampes, I. Harant, Fabien Pillard, Michel Berlan, Claire Thalamas, Marie-Adeline Marques, Max Lafontan, Isabelle de Glisezinski, Cedric Moro

Publikováno v: Obesity (Silver Spring, Md.)
Obesity (Silver Spring, Md.), 2007, 15 (9), pp.2245-55. ⟨10.1038/oby.2007.267⟩

International audience; OBJECTIVE: To explore sex differences in the regulation of lipolysis during exercise, the lipid-mobilizing mechanisms in the subcutaneous adipose tissue (SCAT) of overweight men and women were studied using microdialysis. RESE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1cda2f86b77829c7aaff59614a64cf
https://doi.org/10.1038/oby.2007.267

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Therapeutic use of recombinant methionyl human leptin

Autor: Corinne Vigouroux, Jean-François Gautier, Camille Vatier

Publikováno v: Biochimie
Biochimie, 2012, 94 (10), pp.2116-25. ⟨10.1016/j.biochi.2012.03.013⟩
Biochimie, Elsevier, 2012, 94 (10), pp.2116-25. 〈10.1016/j.biochi.2012.03.013〉
Biochimie, Elsevier, 2012, 94 (10), pp.2116-25. ⟨10.1016/j.biochi.2012.03.013⟩

International audience; Recombinant methionyl human leptin (r-metHuLeptin) was first used as a replacement therapy in patients bearing inactivating mutations in the leptin gene. In this indication, it was shown since 1999 to be very efficient in indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbec53234d12888806e976e1c173ebe
https://doi.org/10.1016/j.biochi.2012.03.013

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Peripheral leptin effect on food intake in young chickens is influenced by age and strain

Autor: Michel Derouet, Mohammed Taouis, Michel Picard, Duane H. Keisler, S Cassy, Sabine Crochet

Publikováno v: Domestic Animal Endocrinology
Domestic Animal Endocrinology, Elsevier, 2004, 27 (1), pp.51-61. ⟨10.1016/j.domaniend.2004.01.004⟩

International audience; The acute effect of leptin on the regulation of food intake was investigated in layer and broiler chickens. In an initial study, we observed that a single intraperitoneal injection of recombinant chicken leptin (1 mg/kg BW) dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409a10f232846c278acc3a622de1e265
https://doi.org/10.1016/j.domaniend.2004.01.004

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Differences in mRNA expression of adipocyte-derived factors in response to fasting, refeeding and leptin

Autor: Thierry Raclot, Fabrice Bertile

Publikováno v: Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2004, 1683 (1-3), pp.101-109. ⟨10.1016/j.bbalip.2004.05.001⟩

International audience; The present study examines whether and to what extent the profiles of adipose-derived factors are altered in epididymal and subcutaneous adipose tissues of long-term fasted/refed and of fasted rats treated by recombinant lepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc7223c7b925b59b2ab67534b65c4ea
https://doi.org/10.1016/j.bbalip.2004.05.001

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Leptin and insulin downregulate leptin receptor gene expression in chicken-derived leghorn male hepatoma cells

Autor: Mohammed Taouis, Sami Dridi, S Cassy, Michel Derouet, Sabine Crochet

Publikováno v: British Poultry Science
British Poultry Science, Taylor & Francis, 2003, 82 (10), pp.1573-1579. ⟨10.1093/ps/82.10.1573⟩

International audience; In chickens, leptin is expressed mainly in the liver, where its receptor gene expression has also been reported, and in adipose tissue. In view of the key role played by the liver in lipogenesis in avian species, the hepatic e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2689fc1b5eb03096fe1241f075ee6df3
https://doi.org/10.1093/ps/82.10.1573

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Leptin Fully Suppresses Acetylcholine-Induced Insulin Secretion and is Reversed by Tolbutamide in Isolated Perfused Chicken Pancreas

Autor: Yacir Benomar, M. Derouet, S. Crochet, Mohammed Taouis, Nicole Rideau

Publikováno v: Hormone and Metabolic Research
Hormone and Metabolic Research, Thieme Publishing, 2003, 35 (2), pp.81-85. ⟨10.1055/s-2003-39055⟩

International audience; So far, there has been no evidence for any direct pancreatic effect of leptin in the chicken. The present study was aimed at detecting chicken leptin receptor (cOb-R) expression in isolated chicken islets of Langerhans and to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf3d72c9a7ee028effeeb8afc36ac75
https://doi.org/10.1055/s-2003-39055

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