Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells

Autor: Sofien Ben Ammou, Anne Vejux, Meryam Debbabi, Stéphane Grégoire, Philippe Durand, Nadia Mekahli, Emmanuelle Camus, Lionel Bretillon, Amira Zarrouk, Maryem Bezine, Lucy Martine, Aymen Jabrane, Gérard Lizard, Mohamed Hammami, Thibault Moreau, Randa Sghaier, Michel Prost, Thomas Nury

Publikováno v: International Journal of Molecular Sciences; Volume 17; Issue 12; Pages: 1973
International Journal of Molecular Sciences 12 (17), 1973. (2016)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2016, 17 (12), pp.E1973. ⟨10.3390/ijms17121973⟩
International Journal of Molecular Sciences, Vol 17, Iss 12, p 1973 (2016)
International Journal of Molecular Sciences, MDPI, 2016, 17 (12), pp.E1973. 〈http://www.mdpi.com/1422-0067/17/12/1973〉. 〈10.3390/ijms17121973〉

Lipid peroxidation products, such as 7-ketocholesterol (7KC), may be increased in the body fluids and tissues of patients with neurodegenerative diseases and trigger microglial dysfunction involved in neurodegeneration. It is therefore important to i

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