Výsledky vyhledávání - "MESH: Keratinocytes / cytology"

The Amino-Terminal Part of Human FLG2 Is a Component of Cornified Envelopes

Autor: Géraldine Albérola, Carine Froment, Michel Simon, Jens-Michael Schröder

Publikováno v: Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2019, 139 (6), pp.1395-1397. ⟨10.1016/j.jid.2018.11.022⟩
Journal of Investigative Dermatology, 2019, 139 (6), pp.1395-1397. ⟨10.1016/j.jid.2018.11.022⟩

International audience; FLG2, a member of the S100-fused type protein family, is a 250-kDa protein expressed mainly in differentiated keratinocytes of the epidermis (Hsu et al.,2011; Wu et al., 2009). Its expression isreduced in atopic dermatitis (Pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bd601f463a5f96d43e5b2b917a2c39
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03180678/file/S0022202X18329142.pdf

Zobrazit plný text záznamu

Rab11a Is Essential for Lamellar Body Biogenesis in the Human Epidermis

Autor: Elise Gaspard, Sophie Allart, Michel Simon, Corinne Leprince, Guy Serre, Marie Reynier, Alain Moga, Dominique Goudounèche

Publikováno v: Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2016, 136 (6), pp.1199-1209. ⟨10.1016/j.jid.2016.02.001⟩
Journal of Investigative Dermatology, 2016, 136 (6), pp.1199-1209. ⟨10.1016/j.jid.2016.02.001⟩

International audience; Most of the skin barrier function is attributable to the outermost layer of the epidermis, the stratum corneum, which is composed of flattened, anucleated cells called corneocytes surrounded by a lipid-enriched lamellar matrix

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7628416d818b5d36f47a70312dac16
https://doi.org/10.1016/j.jid.2016.02.001

Zobrazit plný text záznamu

Lowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown

Autor: Emeline Lhuillier, Hidenari Takahara, Paul R. Thompson, Guy Serre, Valérie Pendaries, Michel Simon, Marie-Claire Méchin, Laura Cau

Publikováno v: Journal of Dermatological Science
Journal of Dermatological Science, 2017, 86 (2), pp.106-113. ⟨10.1016/j.jdermsci.2017.02.280⟩
Journal of Dermatological Science, Elsevier, 2017, 86 (2), pp.106-113. ⟨10.1016/j.jdermsci.2017.02.280⟩

International audience; Background: Deimination (also known as citrullination), the conversion of arginine in a protein to citrulline, is catalyzed by a family of enzymes called peptidylarginine deiminases (PADs). Three PADs are expressed in the epid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3329a089f3a3ec98ecd7c2067a086df
https://ut3-toulouseinp.hal.science/hal-03156353

Zobrazit plný text záznamu

Quantification and Characterization of UVB-Induced Mitochondrial Fragmentation in Normal Primary Human Keratinocytes

Autor: B. Closs, Sylvie Bordes, Abdel Aouacheria, Célia Da Silva, Josselin Breugnot, Romain Jugé

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6 (1), ⟨10.1038/srep35065⟩
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep35065⟩

UV irradiation is a major environmental factor causing skin dryness, aging and cancer. UVB in particular triggers cumulative DNA damage, oxidative stress and mitochondrial dysfunction. The objective of our study was to provide both qualitative and qu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf15385655ef23cec98f71cab15cff6

Zobrazit plný text záznamu

Mice deficient for the epidermal dermokine β and γ isoforms display transient cornification defects

Autor: Nathalie Jonca, Anne Huchenq, Guy Serre, Emilie Leclerc, Sanja Kezic

Publikováno v: Journal of cell science, 127(Part 13), 2862-2872. Company of Biologists Ltd
Journal of Cell Science
Journal of Cell Science, 2014, 127 (13), pp.2862-2872. ⟨10.1242/jcs.144808⟩
Journal of Cell Science, Company of Biologists, 2014, 127 (13), pp.2862-2872. ⟨10.1242/jcs.144808⟩

International audience; Expression of the human dermokine gene (DMKN) leads to the production of four dermokine isoform families. The secreted α, β and γ isoforms have an epidermis-restricted expression pattern, with Dmkn β and γ being specifica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076cfa563f3364839204565896569774
https://pure.amc.nl/en/publications/mice-deficient-for-the-epidermal-dermokine--and--isoforms-display-transient-cornification-defects(df4b76ca-0828-4b59-a52c-ae84d20f7a3e).html

Zobrazit plný text záznamu

High TMEM45A expression is correlated to epidermal keratinization

Autor: Catherine Lambert de Rouvroit, Marie Reynier, Carine Michiels, Aurélie Hayez, Vincent Geenen, Chantal Renard, Michel Simon, Yves Poumay, Jérémy Malaisse, Marek Haftek, Guy Serre, Edith Roegiers

Publikováno v: Experimental Dermatology
Experimental Dermatology, 2014, 23 (5), pp.339-344. ⟨10.1111/exd.12403⟩
Experimental Dermatology, Wiley, 2014, 23 (5), pp.339-344. ⟨10.1111/exd.12403⟩
Hayez, A, Malaisse, J, Roegiers, E, Reynier, M, Renard, C, Haftek, M, Geenen, V, Serre, G, Simon, M, Lambert de Rouvroit, C, Michiels, C & Poumay, Y 2014, ' High TMEM45A expression is correlated to epidermal keratinization ', Experimental dermatology, vol. 23, no. 5, pp. 339-344 . https://doi.org/10.1111/exd.12403

TMEM45A (DERP7, DNAPTP4 or FLJ10134) gene, belonging to the TMEM family encoding predicted transmembrane proteins, is highly expressed in epidermal keratinocytes. To investigate the potential involvement of TMEM45A during the differentiation and kera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271eda0418b0bc6e2e79a735ebe1ac5f
https://doi.org/10.1111/exd.12403

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání