Výsledky vyhledávání - "MESH: Interleukin-18"

Increased CXCR3+ T Cells Impairs Recruitment of T-Helper Type 17 Cells via Interferon γ and Interleukin 18 in the Small Intestine Mucosa During Treated HIV-1 Infection

Autor: Nicolas Carrere, Jacques Izopet, Bertrand Suc, Claire Loiseau, Michelle Cazabat, Pierre Delobel, Mary Requena, Manon Nayrac, Laurent Alric, M Mavigner, A L Iscache

Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, 2019, 220 (5), pp.830-840. ⟨10.1093/infdis/jiz123⟩
Journal of Infectious Diseases, Oxford University Press (OUP), 2019, 220 (5), pp.830-840. ⟨10.1093/infdis/jiz123⟩

The restoration of CD4+ T cells, especially T-helper type 17 (Th17) cells, remains incomplete in the gut mucosa of most human immunodeficiency virus type 1 (HIV-1)–infected individuals despite sustained antiretroviral therapy (ART). Herein, we repo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf1141fb4f0f9aada7cab65629d072a
https://ut3-toulouseinp.hal.science/hal-03355691

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ASC Controls IFN-γ Levels in an IL-18–Dependent Manner in Caspase-1–Deficient Mice Infected with Francisella novicida

Autor: Roberto Pierini, Irmgard Förster, Thomas Henry, Thierry Walzer, Carole Juruj, Marie-Cécile Michallet, Jacqueline Marvel, Magali Perret, Sophia Djebali

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2013, 191 (7), pp.3847-57. ⟨10.4049/jimmunol.1203326⟩
Journal of Immunology, 2013, 191 (7), pp.3847-57. ⟨10.4049/jimmunol.1203326⟩

Remerciements ECOFECT; International audience; The inflammasome is a signaling platform that is central to the innate immune responses to bacterial infections. Francisella tularensis is a bacterium replicating within the host cytosol. During F. tular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03252b54fe580fd6f7bbc207e3018d8f
https://doi.org/10.4049/jimmunol.1203326

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Bruton’s Tyrosine Kinase Is Involved in miR-346-Related Regulation of IL-18 Release by Lipopolysaccharide-Activated Rheumatoid Fibroblast-Like Synoviocytes

Autor: Jean Sibilia, Dominique Wachsmann, Jacques-Eric Gottenberg, Noha Semaan, Ghada Alsaleh, Sébastien Pfeffer, Laurent Frenzel, Tom Juncker, Guillaume Suffert

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 182, pp.5088-5097
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 182 (8), pp.5088-97. ⟨10.4049/jimmunol.0801613⟩

MicroRNAs (miRNAs) have emerged as key players in the regulation of expression of target mRNAs expression. They have been associated with diverse biological processes, and recent studies have demonstrated that miRNAs play a role in inflammatory respo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631d714ef56a05c9c04de8c79e0d6407
https://doi.org/10.4049/jimmunol.0801613

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Cutting Edge: Priming of NK Cells by IL-18

Autor: Nicolas Fuseri, Thierry Walzer, Eric Vivier, Bruce Beutler, Lena Alexopoulou, Laurent Brossay, Marlowe S. Tessmer, Bernhard Ryffel, Marc Dalod, Julie Chaix, Kasper Hoebe

Recent evidence suggests that NK cells require priming to display full effector activity. In this study, we demonstrate that IL-18 contributed to this phenomenon. IL-18 signaling-deficient NK cells were found to be unable to secrete IFN-γ in respons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc17b37ae0d11c0fcdd2bb40eacff2c
https://doi.org/10.4049/jimmunol.181.3.1627

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Acute Plasma Biomarkers of T Cell Activation Set-Point Levels and of Disease Progression in HIV-1 Infection

Autor: Isabelle Girault, Marie-Anne Rey-Cuille, Alain Venet, Yasmine Zitoun, Camille Lécuroux, Beatrice Jacquelin, Gaël Petitjean, Anne-Sophie Liovat, Françoise Barré-Sinoussi, Pierre Lebon, Michaela Müller-Trutwin, Martine Sinet, Laurence Meyer

Publikováno v: PLoS ONE
PLoS ONE, 2012, 7 (10), pp.e46143. ⟨10.1371/journal.pone.0046143⟩
PLoS ONE, Public Library of Science, 2012, 7 (10), pp.e46143. ⟨10.1371/journal.pone.0046143⟩
PLoS ONE, Vol 7, Iss 10, p e46143 (2012)

International audience; T cell activation levels, viral load and CD4 + T cell counts at early stages of HIV-1 infection are predictive of the rate of progression towards AIDS. We evaluated whether the inflammatory profile during primary HIV-1 infecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55f3a41c259ff58d8bfe756a852ac77
http://europepmc.org/articles/PMC3462744

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Interactions between human NK cells and macrophages in response to Salmonella infection

Autor: Nicolas Lapaque, Eric Vivier, Thierry Walzer, John Trowsdale, Stéphane Méresse

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 182 (7), pp.4339-48. ⟨10.4049/jimmunol.0803329⟩
Journal of Immunology, 2009, 182 (7), pp.4339-48. ⟨10.4049/jimmunol.0803329⟩

NK cells play a key role in host resistance to a range of pathogenic microorganisms, particularly during the initial stages of infection. NK cell interactions with cells infected with viruses and parasites have been studied extensively, but human bac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a71f7fc38124b5c79fa11cdc6e88c19
https://pubmed.ncbi.nlm.nih.gov/19299734

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Shiga toxin produced by enterohemorrhagic Escherichia coli inhibits PI3K/NF-kappaB signaling pathway in globotriaosylceramide-3-negative human intestinal epithelial cells

Autor: Thomas Hindré, Alain P. Gobert, Marjolaine Vareille, Anne-Lise Glasser, Thibaut de Sablet, Christine Martin

Shiga toxin (Stx) produced by enterohemorrhagic Escherichia coli (EHEC) binds to endothelial cells expressing globotriaosylceramide-3 (Gb-3) and induces cell death by inhibiting translation. Nonetheless, the effects of Stx on human enterocytes, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedd2af12d9572283110510d3e6c7785
https://hal.archives-ouvertes.fr/hal-00801237

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The effect of the physical characteristics of hydroxyapatite particles on human monocytes IL-18 production in vitro

Autor: Moncef Guenounou, Patrice Laquerriere, Alexia Grandjean-Laquerriere, Dominique Laurent-Maquin, Terry M. Phillips

Publikováno v: Biomaterials
Biomaterials, Elsevier, 2004, 25, pp.5921-7. ⟨10.1016/j.biomaterials.2004.02.003⟩
Biomaterials, 2004, 25, pp.5921-7. ⟨10.1016/j.biomaterials.2004.02.003⟩

Hydroxyapatite (HA) is widely used to coat the metal parts of prosthetic implants in order to improve their biocompatibility and as a bone defect filling material. HA has been demonstrated to produce particles at the prosthetic interface that lead to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb42718222904b3866b752b22d86811
https://www.hal.inserm.fr/inserm-00071342

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IL-8 expression and its possible relationship with estrogen-receptor-negative status of breast cancer cells

Autor: Jean-Paul Brouillet, Anne Licznar, Annick Lucas, Gwendal Lazennec, Françoise Vignon, Matthieu Lacroix, Corine Chauveau, Ariane Freund

Publikováno v: Oncogene
Oncogene, Nature Publishing Group, 2003, 22 (2), pp.256-65. ⟨10.1038/sj.onc.1206113⟩

Estrogen-receptor (ER) status is an important parameter in breast cancer management as ER-positive breast cancers have a better prognosis than ER-negative tumors. This difference comes essentially from the lower aggressiveness and invasiveness of ER-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eda6b46f28e18478aa08492ea8859af
https://www.hal.inserm.fr/inserm-00143840

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