Výsledky vyhledávání - "MESH: Interferon Alfa-2a"

Differential Receptor Subunit Affinities of Type I Interferons Govern Differential Signal Activation

Autor: Gilles Uzé, Jacob Piehler, Martynas Gavutis, Jacques Martal, Eva Jaks

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2007, 366 (2), pp.525-39. ⟨10.1016/j.jmb.2006.11.053⟩

Type I interferons (IFNs) elicit antiviral, antiproliferative and immunmodulatory responses by binding to a shared cell surface receptor comprising the transmembrane proteins ifnar1 and ifnar2. Activation of differential response patterns by IFNs has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad108aba7f871f46390a671dca8e71b6
https://doi.org/10.1016/j.jmb.2006.11.053

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Telaprevir and peginterferon with or without ribavirin for chronic HCV infection.: PROVE2: Telaprevir with PEG-IFN and RBV in HCV

Autor: Hézode , Christophe, Forestier , Nicole, Dusheiko , Geoffrey, Ferenci , Peter, Pol , Stanislas, Goeser , Tobias, Bronowicki , Jean-Pierre, Bourlière , Marc, Gharakhanian , Shahin, Bengtsson , Leif, McNair , Lindsay, George , Shelley, Kieffer , Tara, Kwong , Ann, Kauffman , Robert, Alam , John, Pawlotsky , Jean-Michel, Zeuzem , Stefan

Publikováno v: New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2009, 360 (18), pp.1839-50. ⟨10.1056/NEJMoa0807650⟩
New England Journal of Medicine, Massachusetts Medical Society, 2009, 360 (18), pp.1839-50. 〈10.1056/NEJMoa0807650〉

International audience; BACKGROUND: In patients with chronic infection with hepatitis C virus (HCV) genotype 1, treatment with peginterferon alfa and ribavirin for 48 weeks results in rates of sustained virologic response of 40 to 50%. Telaprevir is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0f5757e84789258ce37e0c6da27dcd82
https://www.hal.inserm.fr/inserm-00385235/file/1839.pdf

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Celiac Disease Is Not Associated with Chronic Hepatitis C

Autor: Thevenot, Thierry, Boruchowicz, Arnaud, Henrion, Jean, Nalet, Bernard, Moindrot, Henri, Renseigné, Non

Publikováno v: Digestive Diseases and Sciences
Digestive Diseases and Sciences, Springer Verlag, 2007, 52 (5), pp.1310-2. ⟨10.1007/s10620-006-9360-5⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83196a72c49a83eda467168c355f7cfa
https://doi.org/10.1007/s10620-006-9360-5

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Design evaluation and optimization for models of hepatitis C viral dynamics

Autor: Jeremie Guedj, Avidan U. Neumann, Caroline Bazzoli

Publikováno v: Statistics in Medicine
Statistics in Medicine, Wiley-Blackwell, 2011, 30 (10), pp.1045-56. ⟨10.1002/sim.4191⟩
Statistics in Medicine, 2011, 30 (10), pp.1045-56. ⟨10.1002/sim.4191⟩

International audience; Mathematical modeling of hepatitis C viral (HCV) kinetics is widely used for understanding viral pathogenesis and predicting treatment outcome. The standard model is based on a system of five non-linear ordinary differential e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd17533ffc8d4276448cace8c70dc3ca
https://www.hal.inserm.fr/inserm-00615142/document

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A GEIL flow cytometry consensus proposal for quantification of plasma cells: Application to differential diagnosis between MGUS and myeloma

Autor: Frébet, Elise, Abraham, Julie, Geneviève, Franck, Lepelley, Pascale, Daliphard, Sylvie, Bardet, Valérie, Amsellem, Sophie, Guy, Julien, Mullier, Francois, Durrieu, Francoise, Venon, Marie-Dominique, Leleu, Xavier, Jaccard, Arnaud, Faucher, Jean-Luc, Béné, Marie C, Feuillard, Jean, Renseigné, Non

Publikováno v: Cytometry Part B Clinical Cytometry
Cytometry Part B Clinical Cytometry, 2010, 363 (26), epub ahead of print. ⟨10.1002/cyto.b.20581⟩
Cytometry Part B: Clinical Cytometry
Cytometry Part B: Clinical Cytometry, Wiley, 2011, 80 (3), pp.176-85. ⟨10.1002/cyto.b.20581⟩

International audience; BACKGROUND:: Flow cytometry is the sole available technique for quantification of tumor plasma-cells in plasma-cell disorders, but so far, no consensus technique has been proposed. Here, we report on a standardized, simple, ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7361e9d3a693ce2d228c45674af1f66d
https://hal.archives-ouvertes.fr/hal-00559641

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Atypical presentation of adult T-cell leukaemia/lymphoma due to HTLV-1: prurigo nodularis lasting twelve years followed by an acute micropapular eruption

Autor: Olivier Cassar, Antoine Petit, Isabelle Moulonguet, Jacqueline Rivet, Antoine Gessain, Daniel Wallach, Félix Agbalika, Arnaud Duval

Publikováno v: Acta Dermato-Venereologica Supplementum
Acta Dermato-Venereologica Supplementum, Society for Publication of Acta Dermato-Venereologica, 2010, 90 (3), pp.287-90. ⟨10.2340/00015555-0846⟩
Acta Dermato-Venereologica Supplementum, 2010, 90 (3), pp.287-90. ⟨10.2340/00015555-0846⟩

International audience; Prurigo nodularis is a pruritic dermatosis of unknown origin. Human T-cell lymphotropic virus type 1 (HTLV-1) causes adult T-cell leukaemia/lymphoma. HTLV-1 is not considered to be a cause of prurigo nodularis. A 52-year-old b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b02eb1936e72e33b42090fd546927e
https://hal-pasteur.archives-ouvertes.fr/pasteur-00531222

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Telaprevir and peginterferon with or without ribavirin for chronic HCV infection

Autor: Hézode, Christophe, Forestier, Nicole, Dusheiko, Geoffrey, Ferenci, Peter, Pol, Stanislas, Goeser, Tobias, Bronowicki, Jean-Pierre, Bourlière, Marc, Gharakhanian, Shahin, Bengtsson, Leif, Mcnair, Lindsay, George, Shelley, Kieffer, Tara, Kwong, Ann, Kauffman, Robert, Alam, John, Pawlotsky, Jean-Michel, Zeuzem, Stefan

Publikováno v: New England Journal of Medicine
New England Journal of Medicine, 2009, 360 (18), pp.1839-50. ⟨10.1056/NEJMoa0807650⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::0f5757e84789258ce37e0c6da27dcd82
https://doi.org/10.1056/NEJMoa0807650

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Efficacy and safety of peginterferon alpha-2a/ribavirin in treatment-naive Cameroonian patients with chronic hepatitis C

Autor: Eric Nerrienet, Michèle Tagni Sartre, Christophe Pasquier, Isabelle Timba, Patrice Tchendjou, Dominique Rousset, Richard Njouom

Publikováno v: Journal of Medical Virology
Journal of Medical Virology, Wiley-Blackwell, 2008, 80 (12), pp.2079-85. ⟨10.1002/jmv.21319⟩

International audience; Data were examined from a day-to-day clinical practice in Yaounde, Cameroon to evaluate the efficacy and safety of peginterferon alfa-2a and ribavirin in treatment-naive Cameroonian patients with chronic hepatitis C. Ninety ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9910915807dafd7c9fafc30ff3a5f8e5
https://pubmed.ncbi.nlm.nih.gov/19040282

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Predicting efficacy and safety outcomes in patients with hepatitis C virus genotype 1 and persistently 'normal' alanine aminotransferase levels treated with peginterferon alpha-2a (40KD) plus ribavirin

Autor: Eric, Snoeck, Stephanos J, Hadziyannis, Claudio, Puoti, Mark G, Swain, Thomas, Berg, Patrick, Marcellin, Jean-Pierre, Zarski, Karin, Jorga, Stefan, Zeuzem

Publikováno v: Liver International
Liver International, Wiley-Blackwell, 2008, 28 (1), pp.61-71. ⟨10.1111/j.1478-3231.2007.01603.x⟩

International audience; BACKGROUND: Currently, the approved dosage of ribavirin has not been studied in patients with 'normal' alanine aminotransferase (ALT) levels. METHODS: Modelling and simulations were performed using generalised additive models

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a006f400992a02d0d43ea3275158e11f
https://www.hal.inserm.fr/inserm-00324956

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IRES complexity before IFN-alpha treatment and evolution of the viral load at the early stage of treatment in peripheral blood mononuclear cells from chronic hepatitis C patients

Autor: Jean-Pierre Zarski, Tania Dufeu-Duchesne, Vincent Leroy, M.A. Thelu, Patrice N. Marche, Muhammad Ramzan

Publikováno v: Journal of Medical Virology
Journal of Medical Virology, 2007, 79 (3), pp.242-53. ⟨10.1002/jmv.20792⟩
Journal of Medical Virology, Wiley-Blackwell, 2007, 79 (3), pp.242-53. ⟨10.1002/jmv.20792⟩

In the proof, we asked to correct the name of one Author, and the adddess; this was acknowledged by the Editor, but was omitted in the final published version!; International audience; At the early stage of treatment, IFN alpha-2a induces inhibition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426ee12ae55b1b9d53be258da1b9335f
https://pubmed.ncbi.nlm.nih.gov/17245718

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