Zobrazeno 1 - 10
of 51
pro vyhledávání: '"MESH: Integrases"'
Autor:
Claire Vit, Xavier Eyer, Vincent Parissi, Florian Fournes, Egill Richard, Didier Mazel, Clemence Whiteway, Céline Loot, Delphine Lapaillerie
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2021, 49 (10), pp.5654-5670. ⟨10.1093/nar/gkab412⟩
Nucleic Acids Research, 2021, 49 (10), pp.5654-5670. ⟨10.1093/nar/gkab412⟩
Integrons are genetic systems conferring to bacteria a rapid adaptation capability. The integron integrase is able to capture, stockpile and shuffle novel functions embedded in cassettes. This involves the recognition of both substrates, theattIsite,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a01301c318589ff672975b1c1743b4
https://doi.org/10.1101/2020.11.24.395434
https://doi.org/10.1101/2020.11.24.395434
Autor:
Céline Loot, Aleksandra Nivina, Guillaume Cambray, Rocío López-Igual, Jose Antonio Escudero, Didier Mazel
Publikováno v:
Biotechnology and Bioengineering
Biotechnology and Bioengineering, 2018, 115 (1), pp.184-191. ⟨10.1002/bit.26450⟩
Biotechnology and Bioengineering, Wiley, 2018, 115 (1), pp.184-191. ⟨10.1002/bit.26450⟩
Biotechnology and Bioengineering, 2018, 115 (1), pp.184-191. ⟨10.1002/bit.26450⟩
Biotechnology and Bioengineering, Wiley, 2018, 115 (1), pp.184-191. ⟨10.1002/bit.26450⟩
Synthetic DNA design needs to harness the many information layers embedded in a DNA string. We previously developed the Evolutionary Landscape Painter (ELP), an algorithm that exploits the degeneracy of the code to increase protein evolvability. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e99e9698b77992f6b570633d0ca4f1b
https://doi.org/10.1002/bit.26450
https://doi.org/10.1002/bit.26450
Autor:
Chloé Guinaudie, Léa C. Perret, Quentin Rainer, Bruno Giros, Alain Gratton, Luc Moquin, Elsa Isingrini
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.12432. ⟨10.1038/s41598-017-12810-9⟩
Scientific Reports, 2017, 7 (1), pp.12432. ⟨10.1038/s41598-017-12810-9⟩
Scientific Reports, Nature Publishing Group, 2017, 7, pp.12432. 〈10.3389/fnana.2014.00155〉
Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.12432. ⟨10.1038/s41598-017-12810-9⟩
Scientific Reports, 2017, 7 (1), pp.12432. ⟨10.1038/s41598-017-12810-9⟩
Scientific Reports, Nature Publishing Group, 2017, 7, pp.12432. 〈10.3389/fnana.2014.00155〉
International audience; The type 2 vesicular monoamine transporter (VMAT2), by regulating the storage of monoamines transmitters into synaptic vesicles, has a protective role against their cytoplasmic toxicity. Increasing evidence suggests that impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb2a4254bbfa20ad278a4677ceaf80c
http://link.springer.com/article/10.1038/s41598-017-12810-9
http://link.springer.com/article/10.1038/s41598-017-12810-9
Autor:
Antonino Nicoletti, Anne Poliard, Catherine Chaussain, Gabriel Castillo‐Dali, Anne-Margaux Collignon, Soledad Acuna-Mendoza, Didier Letourneur, Gaël Y. Rochefort, Thomas Guilbert, Julie Lesieur, Eduardo Gomez
Publikováno v:
STEM CELLS
STEM CELLS, AlphaMed Press, 2019, 37 (5), pp.701-711. ⟨10.1002/stem.2973⟩
Stem Cells / Stem Cells (Miamisburg)
Stem Cells / Stem Cells (Miamisburg), Alphamed Press, 1970, 37 (5), pp.701-711. ⟨10.1002/stem.2973⟩
STEM CELLS, AlphaMed Press, 2019, 37 (5), pp.701-711. ⟨10.1002/stem.2973⟩
Stem Cells / Stem Cells (Miamisburg)
Stem Cells / Stem Cells (Miamisburg), Alphamed Press, 1970, 37 (5), pp.701-711. ⟨10.1002/stem.2973⟩
Stem cells endowed with skeletogenic potentials seeded in specific scaffolds are considered attractive tissue engineering strategies for treating large bone defects. In the context of craniofacial bone, mesenchymal stromal/stem cells derived from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ce58fdf7a25f398d8d28481f16470a
https://hal.archives-ouvertes.fr/hal-02476626
https://hal.archives-ouvertes.fr/hal-02476626
Autor:
Mukhortava, Ann, Pöge, Matthias, Grieb, Maj Svea, Nivina, Aleksandra, Loot, Céline, Mazel, Didier, Schlierf, Michael
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2019, 47 (4), pp.1861-1870. ⟨10.1093/nar/gky1258⟩
NUCLEIC ACIDS RESEARCH
Nucleic Acids Research, 2019, 47 (4), pp.1861-1870. ⟨10.1093/nar/gky1258⟩
Nucleic Acids Research, Oxford University Press, 2019, 47 (4), pp.1861-1870. ⟨10.1093/nar/gky1258⟩
NUCLEIC ACIDS RESEARCH
Nucleic Acids Research, 2019, 47 (4), pp.1861-1870. ⟨10.1093/nar/gky1258⟩
A predominant tool for adaptation in Gram-negative bacteria is the functional genetic platform called integron. Integrons capture and rearrange promoterless gene cassettes in a unique recombination process involving the recognition of folded single-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::067534dc7233b1095c7d95e54af1d890
https://pubmed.ncbi.nlm.nih.gov/30566629
https://pubmed.ncbi.nlm.nih.gov/30566629
Autor:
Michael Schlierf, Didier Mazel, Aleksandra Nivina, Bevan L. Cheeseman, Maj Svea Grieb, Andreas Hartmann
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2017, 45 (18), pp.10555-10563. ⟨10.1093/nar/gkx670⟩
Nucleic Acids Research, 2017, 45 (18), pp.10555-10563. ⟨10.1093/nar/gkx670⟩
Nucleic Acids Research, Oxford University Press, 2017, 45 (18), pp.10555-10563. ⟨10.1093/nar/gkx670⟩
Nucleic Acids Research, 2017, 45 (18), pp.10555-10563. ⟨10.1093/nar/gkx670⟩
International audience; Biologically functional DNA hairpins are found in archaea, prokaryotes and eukaryotes, playing essential roles in various DNA transactions. However, during DNA replication, hairpin formation can stall the polymerase and is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a220a7ec7462766bf5aaa7bb7803628
https://hal-pasteur.archives-ouvertes.fr/pasteur-01688527
https://hal-pasteur.archives-ouvertes.fr/pasteur-01688527
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2017, 45 (5), pp.2714-2723. ⟨10.1093/nar/gkw1309⟩
Nucleic Acids Research, Oxford University Press, 2017, 45 (5), pp.2714-2723. ⟨10.1093/nar/gkw1309⟩
International audience; Prokaryotic adaptive immunity relies on the capture of fragments of invader DNA (protospacers) followed by their recombination at a dedicated acceptor DNA locus. This integrative mechanism, called adaptation, needs both Cas1 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7b04918c8d792275773b9db6629f7fc5
https://hal-polytechnique.archives-ouvertes.fr/hal-01961608/document
https://hal-polytechnique.archives-ouvertes.fr/hal-01961608/document
Autor:
Philippe Glaser, Thierry Naas, Rémy A. Bonnin, Daniel T. Huang, Pierre Bogaerts, Laurent Dortet, Morgane De Laveleye, Delphine Girlich, Youri Glupczynski
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2017, 61 (2), pp.e01697-16. ⟨10.1128/AAC.01697-16⟩
Antimicrobial Agents and Chemotherapy, 2017, 61 (2), pp.e01697-16. ⟨10.1128/AAC.01697-16⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2017, 61 (2), pp.e01697-16. ⟨10.1128/AAC.01697-16⟩
Antimicrobial Agents and Chemotherapy, 2017, 61 (2), pp.e01697-16. ⟨10.1128/AAC.01697-16⟩
Horizontal gene transfer may occur between distantly related bacteria, thus leading to genetic plasticity and in some cases to acquisition of novel resistance traits . Proteus mirabilis is an enterobacterial species responsible for human infections t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82b1ee243e92161c8f29bb391f041ce
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107700
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107700
Autor:
Céline Loot, David Bikard, Vincent Parissi, Jihane Amarir-Bouhram, Jose Antonio Escudero, Didier Mazel
Publikováno v:
Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2014, 196 (4), pp.762-771. ⟨10.1128/JB.01109-13⟩
Journal of Bacteriology, 2014, 196 (4), pp.762-771. ⟨10.1128/JB.01109-13⟩
Journal of Bacteriology, American Society for Microbiology, 2014, 196 (4), pp.762-771. ⟨10.1128/JB.01109-13⟩
Journal of Bacteriology, 2014, 196 (4), pp.762-771. ⟨10.1128/JB.01109-13⟩
Integrons play a major role in the dissemination of antibiotic resistance genes among bacteria. Rearrangement of gene cassettes occurs by recombination between attI and attC sites, catalyzed by the integron integrase. Integron recombination uses an u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef7a5f47da37fad8ca0158cf57703f0
https://doi.org/10.1128/jb.01109-13
https://doi.org/10.1128/jb.01109-13
Autor:
Kenneth D. Vernick, Nicolas Puchot, Catherine Bourgouin, Gareth J Lycett, Emilie Pondeville, Amy Lynd, J. M. Meredith, Paul Eggleston
Publikováno v:
Nature Protocols
Nature Protocols, 2014, 9 (7), pp.1698--1712. ⟨10.1038/nprot.2014.117⟩
Nature Protocols, Nature Publishing Group, 2014, 9 (7), pp.1698--1712. ⟨10.1038/nprot.2014.117⟩
Nature Protocols, Nature Publishing Group, 2014, 9 (7), pp.1698--1712. 〈10.1038/nprot.2014.117〉
Hyper Article en Ligne
HAL-UPMC
Nature Protocols, 2014, 9 (7), pp.1698--1712. ⟨10.1038/nprot.2014.117⟩
Nature Protocols, Nature Publishing Group, 2014, 9 (7), pp.1698--1712. ⟨10.1038/nprot.2014.117⟩
Nature Protocols, Nature Publishing Group, 2014, 9 (7), pp.1698--1712. 〈10.1038/nprot.2014.117〉
Hyper Article en Ligne
HAL-UPMC
International audience; Current transgenic methodology developed for mosquitoes has not been applied widely to the major malaria vector Anopheles gambiae, which has proved more difficult to genetically manipulate than other mosquito species and dipte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2346b268a6bf29877b1f362030208d4
https://hal-pasteur.archives-ouvertes.fr/pasteur-02008325
https://hal-pasteur.archives-ouvertes.fr/pasteur-02008325