Zobrazeno 1 - 10
of 129
pro vyhledávání: '"MESH: Insulin Resistance"'
Autor:
Séverine Ledoux, Nathalie Boulet, Chloé Belles, Alexia Zakaroff-Girard, Arnaud Bernard, Albéric Germain, Pauline Decaunes, Anaïs Briot, Jean Galitzky, Anne Bouloumié
Publikováno v:
Cells; Volume 11; Issue 22; Pages: 3540
Cells
Cells, 2022, 11 (22), pp.3540. ⟨10.3390/cells11223540⟩
Cells
Cells, 2022, 11 (22), pp.3540. ⟨10.3390/cells11223540⟩
International audience; Adipose tissue (AT) expansion either through hypertrophy or hyperplasia is determinant in the link between obesity and metabolic alteration. The present study aims to profile the unhealthy subcutaneous and visceral AT (SAT, VA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fa5f27b270b375c68839e6a21f25b8
Autor:
Pires, Karla, Buffolo, Márcio, Pires, Karla Maria, Ferhat, Maroua, Ilkun, Olesya, Makaju, Aman, Achenbach, Alan, Bowman, Faith, Atkinson, Donald, Holland, William, Amri, Ez-Zoubir, Chaurasia, Bhagirath, Franklin, Sarah, Boudina, Sihem
Publikováno v:
Cell Reports, Vol 29, Iss 2, Pp 270-282.e5 (2019)
Cell Reports
Cell Reports, Elsevier Inc, 2019, 29 (2), pp.270-282.e5. ⟨10.1016/j.celrep.2019.08.092⟩
Cell Reports
Cell Reports, Elsevier Inc, 2019, 29 (2), pp.270-282.e5. ⟨10.1016/j.celrep.2019.08.092⟩
Summary: Accumulation of visceral (VIS) is a predictor of metabolic disorders and insulin resistance. This is due in part to the limited capacity of VIS fat to buffer lipids allowing them to deposit in insulin-sensitive tissues. Mechanisms underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4365030bdf687401d0884853a5ec4b82
http://www.sciencedirect.com/science/article/pii/S2211124719311544
http://www.sciencedirect.com/science/article/pii/S2211124719311544
Autor:
Ophélie Pereira, Jean Personnaz, Céline Saint-Laurent, Toshiyuki Araki, Maithé Tauber, Jean-Pierre Salles, Philippe Valet, Adélaïde Gélineau, Mickaël Canouil, Romain Paccoud, Armelle Yart, Jacques Weill, Jean-Philippe Pradere, Mylène Tajan, Cédric Dray, Enzo Piccolo, Sophie Le Gonidec, Inès Baba, Thomas Edouard, Emmanuel L. Gautier, Haoussa Askia, Philippe Froguel, Benjamin G. Neel, Nicolas Beton, Simon Deleruyelle, Johanna Auriau, Sophie Branka, Alizée Dortignac, Maxime Branchereau, Isabelle Castan, Christophe Heymes, Rémy Burcelin, Julie Charpentier
Publikováno v:
Science Translational Medicine
Science Translational Medicine, 2021, 13 (591), ⟨10.1126/scitranslmed.abe2587⟩
Science Translational Medicine, 2021, 13 (591), ⟨10.1126/scitranslmed.abe2587⟩
Insulin resistance is a key event in type 2 diabetes onset and a major comorbidity of obesity. It results from a combination of fat excess-triggered defects, including lipotoxicity and metaflammation, but the causal mechanisms remain difficult to ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0759a52fdb1a01c71a072f9141a84623
https://doi.org/10.1126/scitranslmed.abe2587
https://doi.org/10.1126/scitranslmed.abe2587
Autor:
Araiz, Caroline, Yan, Anqi, Bettedi, Lucia, Samuelson, Sam, Virtue, Sam, McGavigan, Anne, Dani, Christian, Vidal-Puig, Antonio, Foukas, Lazaros, Samuelson, Isabella
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.1546. ⟨10.1038/s41467-019-09514-1⟩
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.1546. ⟨10.1038/s41467-019-09514-1⟩
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The insulin/IGF-1 signalling pathway is a key regulator of metabolism and the rate of ageing. We previously documented that systemic inactivation of phosphoinositide 3-kinase (PI3K) p110α, the principal PI3K isoform that positively regulates insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321bf191e6412be17e44cf270e4acb4e
https://hal.archives-ouvertes.fr/hal-02189498
https://hal.archives-ouvertes.fr/hal-02189498
Autor:
Jacques Grober, Vladimir Stich, Philippe Gui, Corinne Lefort, Geneviève Tavernier, Virginie Bourlier, Isabelle K. Vila, Lenka Rossmeislová, Lucile Mir, Katie Louche, Anne Bouloumié, Nathalie Viguerie, Pierre Marie Badin, Balbine Roussel, Alexia Zakaroff-Girard, Dominique Langin, Cedric Moro, Marie Adeline Marques, Laurent Monbrun
Publikováno v:
Plant Cell Reports
Plant Cell Reports, Springer Verlag, 2014, 7 (4), pp.1116-29. ⟨10.1016/j.celrep.2014.03.062⟩
Plant Cell Reports, 2014, 7 (4), pp.1116-29. ⟨10.1016/j.celrep.2014.03.062⟩
Plant Cell Reports, Springer Verlag, 2014, 7 (4), pp.1116-29. 〈10.1016/j.celrep.2014.03.062〉
Cell Reports, Vol 7, Iss 4, Pp 1116-1129 (2014)
Plant Cell Reports, Springer Verlag, 2014, 7 (4), pp.1116-29. ⟨10.1016/j.celrep.2014.03.062⟩
Plant Cell Reports, 2014, 7 (4), pp.1116-29. ⟨10.1016/j.celrep.2014.03.062⟩
Plant Cell Reports, Springer Verlag, 2014, 7 (4), pp.1116-29. 〈10.1016/j.celrep.2014.03.062〉
Cell Reports, Vol 7, Iss 4, Pp 1116-1129 (2014)
International audience; Adipose tissue fibrosis development blocks adipocyte hypertrophy and favors ectopic lipid accumulation. Here, we show that adipose tissue fibrosis is associated with obesity and insulin resistance in humans and mice. Kinetic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df837893de69950a1c12c20e721bd3d
https://doi.org/10.1016/j.celrep.2014.03.062
https://doi.org/10.1016/j.celrep.2014.03.062
Autor:
Carlos Labat, Simon Verhulst, Kirsten Ohm Kyvik, Athanase Benetos, Kaare Christensen, Christine Dalgård, Simon Toupance, Masayuki Kimura, Abraham Aviv, Jeremy D. Kark
Publikováno v:
Diabetologia
Diabetologia, Springer Verlag, 2016, 59 (6), pp.1258-1265. ⟨10.1007/s00125-016-3915-6⟩
Diabetologia, 59(6), 1258-1265. SPRINGER
Verhulst, S, Dalgård, C, Labat, C, Kark, J D, Kimura, M, Christensen, K, Toupance, S, Aviv, A, Kyvik, K O & Benetos, A 2016, ' A short leucocyte telomere length is associated with development of insulin resistance ', Diabetologia, vol. 59, no. 6, pp. 1258-1265 . https://doi.org/10.1007/s00125-016-3915-6
Diabetologia, Springer Verlag, 2016, 59 (6), pp.1258-1265. ⟨10.1007/s00125-016-3915-6⟩
Diabetologia, 59(6), 1258-1265. SPRINGER
Verhulst, S, Dalgård, C, Labat, C, Kark, J D, Kimura, M, Christensen, K, Toupance, S, Aviv, A, Kyvik, K O & Benetos, A 2016, ' A short leucocyte telomere length is associated with development of insulin resistance ', Diabetologia, vol. 59, no. 6, pp. 1258-1265 . https://doi.org/10.1007/s00125-016-3915-6
AIMS/HYPOTHESIS: A number of studies have shown that leucocyte telomere length (LTL) is inversely associated with insulin resistance and type 2 diabetes mellitus. The aim of the present longitudinal cohort study, utilising a twin design, was to asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61bb9c1a3a8c5eb4acdfc4db643e953
https://hdl.handle.net/11370/d4fe3c05-4374-49da-b2d2-6f1096cbd9e8
https://hdl.handle.net/11370/d4fe3c05-4374-49da-b2d2-6f1096cbd9e8
Autor:
Poyot, T., Couturier, K., Roussel, A.M., Hininger-Favier, I., Marissal-Arvy, Nathalie, Campas, Marie-Neige, Semont, Audrey, Ducroix-Crepy, Céline, Beauvieux, Marie-Christine, BROSSAUD, Julie, Corcuff, Jean-Benoit, HELBLING, Jean-Christophe, Vancassel, Sylvie, Bouzier-Sore, Anne-Karine, Touyarot, Katia, Ferreira, Guillaume, Barat, Pascal, Moisan, Marie-Pierre, Canini, Frédéric, Qin, Bolin, ARVY, Nathalie, Poulet, Laurent, Batandier, Cécile, Roussel, Anne-Marie, Anderson, Richard
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2018, 13 (5), pp.e0197094. ⟨10.1371/journal.pone.0197094⟩
PLoS ONE, Public Library of Science, 2018, 13 (5), pp.1-15. ⟨10.1371/journal.pone.0197094⟩
PLoS ONE, Public Library of Science, 2018, 13 (5), ⟨10.1371/journal.pone.0197094⟩
Plos One 5 (13), 1-15. (2018)
PLoS ONE, 2018, 13 (5), pp.e0197094. ⟨10.1371/journal.pone.0197094⟩
PLoS ONE, Vol 13, Iss 5, p e0197094 (2018)
PLoS ONE, 2018, 13 (5), pp.1-15. ⟨10.1371/journal.pone.0197094⟩
PLoS ONE, Public Library of Science, 2018, 13 (5), pp.e0197094. ⟨10.1371/journal.pone.0197094⟩
PLoS ONE, Public Library of Science, 2018, 13 (5), pp.1-15. ⟨10.1371/journal.pone.0197094⟩
PLoS ONE, Public Library of Science, 2018, 13 (5), ⟨10.1371/journal.pone.0197094⟩
Plos One 5 (13), 1-15. (2018)
PLoS ONE, 2018, 13 (5), pp.e0197094. ⟨10.1371/journal.pone.0197094⟩
PLoS ONE, Vol 13, Iss 5, p e0197094 (2018)
PLoS ONE, 2018, 13 (5), pp.1-15. ⟨10.1371/journal.pone.0197094⟩
International audience; In occidental societies, high fat and high sugar diets often coincide with episodes of stress. The association is likely to modify brain energy control. Brain insulin signalling is rarely studied in stressed individuals consum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71e80f31076fd53f893a1342fd92c53
https://hal.inrae.fr/hal-03349590
https://hal.inrae.fr/hal-03349590
Autor:
Fabio Marra, Sophie Lotersztajn
Publikováno v:
Current Pharmaceutical Design
Current Pharmaceutical Design, Bentham Science Publishers, 2013, 19 (29), pp.5250-69
Current Pharmaceutical Design, 2013, 19 (29), pp.5250-69
Current Pharmaceutical Design, Bentham Science Publishers, 2013, 19 (29), pp.5250-69
Current Pharmaceutical Design, 2013, 19 (29), pp.5250-69
International audience; Non alcoholic steatohepatitis (NASH) is the more severe form of nonalcoholic fatty liver disease. In NASH, fatty liver, hepatic inflammation, hepatocyte injury and fibrogenesis are associated, and this condition may eventually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc05ad2c25e7e0bc662dd64438cc757c
https://doi.org/10.2174/13816128113199990344
https://doi.org/10.2174/13816128113199990344
Autor:
Victoria Serhiyenko, Mykhailo Pliatsko, Peter Eckl, Françoise Guéraud, Andriy Cherkas, Sergii Golota, Orest Abrahamovych, Ostap Yatskevych
Publikováno v:
Croatian Medical Journal
Croatian Medical Journal, Medicinska naklada, Zagreb, 2016, 57 (2), pp.141-149. ⟨10.3325/cmj.2016.57.141⟩
Croatian Medical Journal 2 (57), 141-+. (2016)
Croatian Medical Journal, Medicinska naklada, Zagreb, 2016, 57 (2), pp.141-149. ⟨10.3325/cmj.2016.57.141⟩
Croatian Medical Journal 2 (57), 141-+. (2016)
Helicobacter pylori (H.pylori) is a widely spread infection causing major gastroenterological diseases like chronic gastritis, peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma (1). In addition, several extragastric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f0909ad329816edc659a332db9945b
https://hal.archives-ouvertes.fr/hal-02940500
https://hal.archives-ouvertes.fr/hal-02940500
Autor:
C. Sanchez, Marjorie Poggi, Stéphane Tanguy, Pierre-Emmanuel Morange, Michel Grino, Jean-Charles Martin, Anne Dutour, Marie-Christine Alessi, Catherine Defoort
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, 2012, 32 (10), pp.2394-404. ⟨10.1161/ATVBAHA.112.250332⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2012, 32 (10), pp.2394-404. ⟨10.1161/ATVBAHA.112.250332⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, 2012, 32 (10), pp.2394-404. ⟨10.1161/ATVBAHA.112.250332⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2012, 32 (10), pp.2394-404. ⟨10.1161/ATVBAHA.112.250332⟩
Objective— High endogenous thrombin potential (ETP) is associated with venous and arterial thrombosis. Better knowledge of environmental influences on ETP may help to prevent thrombosis. Methods and Results— Weaning rats exhibited high ETP values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20da49ab6facd1b8ff091b36c79fd455
https://doi.org/10.1161/atvbaha.112.250332
https://doi.org/10.1161/atvbaha.112.250332